Award Data

Ischemic stroke is a leading cause of death and disability in the United States. This often is attributable to thrombus formation at an atherosclerotic plaque or thromboembolism. Patients who present within 4.5 hours of symptom onset are eligible for thrombolysis with tissue plasminogen activator (tPA). This serves andlt;5% of victims. Recently, major advance has been made with proven efficacy fro ...

ABSTRACT SUMMARY In previous studies we identified novel non hematopoietic umbilical cord blood stem cellsnhUCBSCsthat could be expanded to high passages and exhibit restorative properties following ischemic brain injury repairWe found that the high passaged cells were equivalentif not even betterthan the low passaged nh UCBSCsThis finding suggests that these cells can serve as a source of highly ...

Project Summary Abstract The brain is by far the most complex and heterogeneous organ in the human bodyFor yearsthere has been a growing and unmet need to develop multielectrode arrays for neurotransmitter sensing in multiple brain regions simultaneouslyDisparate brain regions such as the nucleus accumbensstriatumprefrontal cortexhippocampusand others have been widely known to have greatly varying ...

Falls are a significant source of early morbidity and mortality in the aging population, yet the neurological,sensory, and motor changes that lead to increased fall risk often escape early identification and intervention. Vital signs are commonly used in clinical settings to assess the cardiovascular system (blood pressure, heart rate), immune system (body temperature), and the respiratory system ...

Project Summary Galactic Core LLC aims to develop a robust, scalable, and managed service for performing enterprise-grade biomedical data analysis. The service will be based on the popular open-source Galaxy application (​https://galaxyproject.org/​), offering unlimited data storage and compute capabilities with an extremely powerful, flexible, and collaborative environment for analyzing data. ...

The problem addressed in this effort is to automatically learn historical ephemeris space catalog time, position, and velocity entity track update error uncertainties (i.e., without track error covariances) and to automatically (e.g., without expert event labeling) produce: – unmodeled non-gravitational space catalog update flags – abnormal unmodeled catalog update flags with abnorma ...

ABSTRACT This supplement project will expand on our current STTR Phase I project in which we partnered with University of Rochesterandapos;s Environmental Health Sciences Center to develop three Science Take-Out vaping education kits. Our vaping education kits involve students in using hands-on activities and real-life scenarios to investigate the harmful effects of chemicals used in e-cigarette f ...

Near-Earth space environment is hazardous to satellites. This harsh particle radiation can penetrate protective shielding, accumulate in sensitive materials and can damage even well shielded electronic components causing temporary malfunctions or a complete system/mission loss. The goal of the proposed work is to provide the Air Force with a state-of-the-art model of the outer zone energetic elect ...

Spectral Energies proposes to design a multisensory diagnostic suite for measurements within elevated-pressure RDEs. This sensor will utilize tunable-laser absorption spectroscopy to measure temperature, pressure and H2O concentrations in the annulus of a rocket-RDE and background-oriented schlieren imaging system for flow density gradient imaging to provide time resolved information about the sho ...

Ocean surface winds are critically important in naval operations. They may aid, hinder, or negate maneuvers and operations, and are a primary consideration in routing ships. Continuous and reliable information on favorable and unfavorable sea state is critical for a broad range of naval missions, including strategic ship movement and positioning, aircraft carrier operations, aircraft deployment, e ...