Award Data

We present the National Incident Visualization System, NIVS. NIVS is a combination of software elements that leverage the capabilities and prevalence of smart-phone technology to create a single point of reference for aggregated information and information sharing during a fire-based emergency at an airport. NIVS aggregates GPS location and status information from personnel and resources with Airp ...

About 40% of trauma-related deaths are related to rapid onset of coagulopathy and the vast majority of trauma patients are coagulopathic at the time of death. Lynntech proposes to develop a novel, easy-to-use and cost effective device for simultaneous quantitative real-time detection of multiple proteins involved in the hemostatic mechanism, using human unprocessed whole blood as the input sample. ...

Integrated Clinical Environments (ICE) rely heavily on medical devices that need to be protected from security threats without compromising patient health and safety. There is a need to assess clinical workflow configurations in terms of security, usability, and efficiency. Currently, each medical device has its own security controls. Access to multiple devices in the integrated environment requir ...

The objective of this study is to demonstrate the efficacy and broad applicability of the human immune-modulating alphaGal Adjuvant Technology for antiviral vaccine development. We will use viral vaccine candidates for the select Category A viral pathogens Zaire ebolavirus (ZEBOV, filovirus), Rift Valley fever virus (RVFV, bunyavirus), and Lassa virus (LV, arenavirus), to evaluate the adjuvant pot ...

Bioassays employed to evaluate the diverse range of biomarkers associated with organ injury are time-consuming, costly and require multiple instruments/testing formats to reach a diagnosis (i.e. fluorescence-based capture, ELISAs, PCR, etc.). Individually, these platforms are incapable of predicting the onset of irreversible organ tissue injury (e.g. kidney, liver, heart and lung). If a single mul ...

Autorack cars transport one of the most valuable commodities – fully assembled Automobiles. Due to the longer and higher profile of an Autorack and the fact that heavy automobiles are loaded on to high deck levels, freight trucks with improved track-to-vehicle dynamics as well as higher speed capabilities are desired in anticipation of higher speed passenger service and shared corridors. Unique ...

Mimosa Acoustics will develop a portable binaural audiological device, based on our successful HearID system. HearID is a clinical system for otoacoustic emission and middle-ear power analysis testing; it is FDA and CE-marked. The new system will have the ability to conduct a variety of audiological tests especially for use in hearing-conservation programs, including: flexible otoacoustic emission ...

We propose to take our hearing-test device, which was designed to support research in advancing hearing-conservation programs, and ruggedize it for use in theater. Five key challenges that make the commercial-off-the-shelf OAE systems unsuitable for HCPs, will be overcome. We will: 1) implement next-generation otoacoustic emission tests to enable OAE measurements in noise-damaged ears, 2) add smar ...

Historically organophosphorus compounds such as insecticides and nerve agents have been susceptible to decomposition by proteinaceous enzymes. Organophosphate hydrolases (OPH) represent a practical method to deactivate such compounds peripherally and on surfaces. However, when such organophosphates are ingested, the use of proteinaceous enzymes such as OPH can be problematic because of their tende ...

The vast majority of injuries in recent military conflicts have been inflicted by improvised explosive devices (IEDs) causing brain, extremities and genital-urinary injuries. Advanced computational models of IED blast physics and human body injury biomech