Award Data

"This Phase I SBIR proposal is for the initial development of a miniaturized real-time visible/UV spectrometer based on micro-opto-electro-mechanical systems (MOEMS) technology. Use of MOEMS technology enables orders of magnitude reductions in size, weightand power from the smallest spectrometers commercially available today and virtually assures exceeding stated corresponding SBIR requirements. ...

The overall objective of this Phase II proposal is to determine the advantages of imidazenil over diazepam or midazolam as a potential anticonvulsant agent for the prophylaxis and for the emergency treatment of organophosphate nerve agent exposure. Therefore, we will compare the dose-dependent efficacy and anticonvulsant tolerance liability of imidazenil or midazolam for protecting rats against di ...

This Phase I SBIR proposal presents the Torch Technologies approach for the development of advanced, innovative, robust real-time algorithms for the integration of passive and active electro-optical sensor detections and identification information. In our proposal, we detail our ideas regarding the optimal fusion of Chemical Warfare (CW) agent sensor data within the innovative data fusion archite ...

"The present proposal describes strategies leading to the development of an array-based universal biosensor for detecting and differentiating microbial species, or differentiating at the DNA or RNA level between cell types of the same species. The proposed strategy relies on the differential hybridization of genomic DNA, extrachromosomal DNA, mRNA, or ribosomal RNA from different sources to a comm ...

"OmniSite BioDiagnostics, Inc. (OmniSite) proposes to develop DNA Aptamers to Bacillus anthracis (nonpathogenic Sterne strain) spores and staphylococcal enterotoxin B (SEB) by the SELEX process. Aptamers are less expensive than antibodies to produce, do notrequire animal hosts for production, can be protected from nucleases, and used in a variety of assay formats to replace antibodies. In Phase I, ...