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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Investigation of a nanoparticle albumin-bound mTOR inhibitor, nab-rapamycin for t

    SBC: AADI, LLC            Topic: 102

    DESCRIPTION provided by applicant In it is estimated that there will be new bladder cancer cases in the United States resulting in deaths Most cases present with nonmuscle invasive bladder cancer NMIBC Intravesical bacillus Calmette Guerin BCG which elicits a nonspecific local immune response is considered the standard first line treatment However ...

    STTR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  2. Safety and efficacy evaluation of the double fiber bundle dialyzer

    SBC: MIRIMEDICAL, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): The USRDS (US Registry of Kidney Failure Patients) states that at the end of 2005, there were 314,000 (prevalent) hemodialysis patients in the U.S., with 97,000 newly diagnosed (incident) end stage renal disease (ESRD) patients receiving hemodialysis. Unfortunately, the one year survival for hemodialysis patients is 78%, which has not improved in the last decad ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  3. Whole Brain Nanoscale Preservation Imaging

    SBC: Nectome Inc.            Topic: 101

    Abstract Summary Nectome will create technologies to enable whole brain nanoscale preservation and imaging a vital step towards a deep understanding of the mind and of the brainandapos s diseases Current brain processing technologies compromise between whole brain applicability or nanoscale resolution our technologies will achieve both si multaneously Similar to the way that next generation ...

    STTR Phase I 2016 Department of Health and Human ServicesNational Institutes of Health
  4. Solving Sepsis: Early Identification and Prompt Management Using Machine Learning

    SBC: Cohere-Med, Inc.            Topic: 300

    Abstract This fast-track STTR application proposes to enhance, validate, and scale Sepsis Watch, a deep learning sepsis detection and management system built using data from the Emergency Department (ED) Duke University Hospital (DUH). The proposal will extend and enhance Sepsis Watch to EDs, general inpatient wards, and intensive care unit (ICU) settings across multiple health systems in the Unit ...

    STTR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  5. PD Wii: Computer-Based Training Phase II

    SBC: RED HILL STUDIOS            Topic: N/A

    DESCRIPTION (provided by applicant): Red Hill Studios and the University of California, San Francisco (UCSF) School of Nursing proposes to develop a computer-based videogame training program for patients with Parkinson's disease (PD). The program will feature a customizable Physical Gaming Regimen that will be based on an existing training program that has proven to be effective in improving gait ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  6. High Throughput Genotyping Technology

    SBC: PARALLELE BIOSCIENCE, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The Molecular Inversion Probe technology has been developed to allow 1000 SNPs to be called in a single tube. This technology holds the promise of enabling large scale inexpensive genetic analysis including the analysis of whole genomes. Before such studies can be contemplated, further platform development is required. Software tools must be developed to proces ...

    STTR Phase II 2003 Department of Health and Human ServicesNational Institutes of Health
  7. Developmental Disabilities Dentistry Online

    SBC: PRAXIS, INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Individuals with intellectual and developmental disabilities (I/DD) have more untreated caries and a higher prevalence of gingivitis and other periodontal diseases than the general population (NIDCR, 2009). In order to address this health care disparity, more dentists are needed who understand and are trained to meet the needs of this population. Few in-depth ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Numerical Tools for Predicting Drug Dissolution Profiles

    SBC: RES Group, Inc.            Topic: NIGMS

    Project SummaryNumerical Tools for Predicting Drug Dissolution Profiles This STTR Phase II proposal describes the development of a modeling framework that combines a mesoscopic model for hydrodynamics with disintegration and dissolution kinetic models in order to accurately describe the dissolution behavior of tabletsThe complexities of the tablet dissolution problem have led to the development of ...

    STTR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  9. ORAL THERAPEUTIC FOR INDUCING FETAL HEMOGLOBIN

    SBC: Gene Regulation Laboratories            Topic: N/A

    DESCRIPTION (provided by applicant): Sickle cell disease (SCD) and beta-thalassemia are genetic disorders caused by molecular mutations affecting the genes for adult hemoglobin. With a world-wide birth prevalence of 2/1,000, hemoglobin disorders are the most common genetic diseases in the world (360,000 patients/year - 250,000 with sickling disorders and 110,000 with thalassemias. These conditions ...

    STTR Phase II 2002 Department of Health and Human ServicesNational Institutes of Health
  10. Broadly Accessible Technologies for Single-cell Joint Analysis of Transcriptome and Epigenome

    SBC: EPIGENOME TECHNOLOGIES, INC.            Topic: 101

    AbstractHistone modifications carry rich information of cellular memory and gene regulatory mechanisms. Single cell analysis of histone modification in conjunction with transcriptome could recover this critical layer of cell identity and help to dissect the cellular and molecular composition of complex tissues such as the brain. We recently developed an ultra-high throughput single cell multi-omic ...

    STTR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
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