You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

  1. Using advanced natural language processing to facilitate documentation of meaningful use and quality payment compliance

    SBC: Safermed, LLC            Topic: NLM

    PROJECT SUMMARY The Center for Medicare and Medicaid Services Quality Payment Program is designed to motivate healthcare providers to adhere to best practices in clinical healthcare and patient safetyUnfortunatelyextracting quality measures data from the clinical record is burdensome and as suchparticipation among clinical healthcare providers is suboptimalOur aim is to develop a system to facilit ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Chemical Libraries Targeting Epigenetic Methyl Writers and Erasers

    SBC: Epicypher, Inc.            Topic: 102

    PROJECT SUMMARYIn this proposalEpiCypher is partnering with DrJian Jina leader in medicinal chemistry and epigenetic drug discoveryto develop the first epigenetics focused chemical library for histone methylationSmall molecule inhibitors that target histone methylation are an emerging class of therapeutics for cancer treatmentThis hot bed of drug development is fueled by the identification of nume ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  3. Fluorescent nanofoldamers for multiplex flow cytometry

    SBC: Nirvana Sciences, Inc.            Topic: 400

    PROJECT SUMMARY ABSTRACT Polychromatic flow cytometryFCis one of the most powerful analytical techniques used in immunologybasic researchand clinical medicineIn basic researchFC is a primary tool for understanding disease development at the cellular and subcellular levelsIn the rapidly developing field of immunotherapyFC is an indispensable tool for monitoring the effectiveness of new therapies an ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  4. Genome-wide CRISPR screen to identify pro-myogenic factors for cell therapy of DMD

    SBC: MYOFINITY BIOSCIENCES INC            Topic: NIAMS

    Project Abstract Myos Incis developing a cell therapy treatment for patients with Duchenne muscular dystrophyDMDbased on HLA matched donor cells that are pretreated with small molecule cocktails ex vivo to modify genes that will enhance engraftment and fusion and enable muscle regenerationMyos is collaborating with DrLouis KunkelBoston Children s Hospitalto address the issues that led to low effic ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  5. Making Standing Balance The Fifth Vital Sign in Clinical Settings

    SBC: BERTEC CORP            Topic: NIA

    Falls are a significant source of early morbidity and mortality in the aging populationyet the neurologicalsensoryand motor changes that lead to increased fall risk often escape early identification and interventionVital signs are commonly used in clinical settings to assess the cardiovascular systemblood pressureheart rateimmune systembody temperatureand the respiratory systemrespiratory rateto e ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  6. Astrocyte activation by small-molecule ADORA3 agonists: a novel therapy for Alzheimer's disease

    SBC: ASTROCYTE PHARMACEUTICALS INC.            Topic: NIA

    PROJECT SUMMARY Alzheimerandapos s diseaseADis an area of significant unmet need that creates a national burden of$billion annuallyAD is the leading cause of dementiaaffectingof Americans over the age ofDemographic shifts and the age related nature of AD will soon place this disease as the costliest health care expenditure in the U Swith a projected impact of $trillion per year byCurrent therapies ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  7. A practical platform for in-home remote monitoring of cognitive-frailty

    SBC: BIOSENSICS LLC            Topic: NIA

    AbstractCognitive frailtythe combined presence of physical frailty and cognitive impairmentis a strong and independent predictor of cognitive declineThe International Association of Gerontology and Geriatrics and the International Academy on Nutrition and Aging have recommended the use of cognitive frailty assessment to track the progression of mild cognitive impairmentMCItowards dementiaAlzheimer ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  8. Enhanced Software Tools for Detecting Anatomical Differences in Image Data Sets

    SBC: KITWARE INC            Topic: 105

    Project Summary Morphometric analysis is a primary algorithmic tool to discover disease and drug related effects on brain anatomy. Neurological degeneration and disease manifest in subtle and varied changes in brain anatomy that can be non-local in nature and effect amounts of white and gray matter as well as relative positioning and shapes of local brain anatomy. State-of-the-art morphometry meth ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Spleen Tyrosine Kinase (SYK) negative allosteric modifiers for therapeutic intervention in Alzheimer's disease.

    SBC: ARCHER PHARMACEUTICALS, INC.            Topic: NIA

    Pathological hallmarks of Alzheimerandapos s diseaseADinclude extracellular deposits of Apeptidesintraneuronal aggregates of abnormally phosphorylated tau protein and neuroinflammationMost proposed AD disease modifying therapies have focused on strategies that reduce brain Aamyloid or tau pathological accumulationHoweversuch approaches have been unsuccessful in late stage AD clinical trials and ma ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
  10. Digital Accessible Remote Olfactory Mediated Health Assessments for Preclinical AD

    SBC: MASSACHUSETTS GENERAL HOSPITAL            Topic: NIA

    Abstract Overmillion Americans are currently affected by Alzheimerandapos s diseaseADwith an economic burden estimated at andgt$billion year inthat is projected increase at least four fold over next several decadesIn spite of the dearth of pharmacological options to modify the course of the disease at presentthe field has developed accurate biomarkers that demonstrate that the pathology of AD is p ...

    STTR Phase I 2018 Department of Health and Human ServicesNational Institutes of Health
US Flag An Official Website of the United States Government