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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201301 - 201310 of 207725 results
  1. Mobile Motivation for Health Promotion Among Adolescents

    SBC: ADVANCED MRI TECHNOLOGIES LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): MRI cerebral perfusion imaging is a widely disseminated technique on nearly all MRI scanners used for clinical diagnosis of brain disease and for neuroscience research. Over the last five years there has been considerably increased use of arterial spin labeling (ASL) for clinical diagnosis, while still i.v. injections of a gadoliium based contrast bolus are wid ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Label-free platform for applications in drug discovery

    SBC: SENSIQ TECHNOLOGIES, INC.            Topic: NCATS

    DESCRIPTION: Incremental improvements in label free screening technologies over the past decade have not produced the capability necessary to support the changing needs of drug discovery programs. Persistent artifacts related to non-specific binding, promiscuous binding, precipitation, complex binding, tubing retention, aggregation, and sub-optimally designed platforms continue to hinder progress ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Targeted Docetaxel-Nanocolloid for the Treatment of Ovarian Cancer

    SBC: NEMUCORE MEDICAL INNOVATIONS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): PROJECT SUMMARY This proposal is a Phase 1 proposal in response to The National Institute of Health Small Business Innovation Research (SBIR) Program call for proposals for the Cancer Diagnostics and Therapeutic AgentsEnabled By Nanotechnology (SBIR [U43/U44]) [Program Announcement Number: PA-10-286]. Nemucore Medical Innovation, Inc.'s (NMI) goal for thi ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Aluminum Oxide Nanoparticles Conjugated to Antigens Potently Induce Tumor Specifi

    SBC: UBIVAC, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): PROJECT SUMMARY Although prophylactic vaccines have potential for prevention of high risk human papilloma virus (HPV) infection they have no therapeutic efficacy. It has been estimated that there will be no measurable decline of HPV- associated tumors before 2040 (Hellner et al., 2011). Likewise, other HPV-associated angogenital and head and neck cancers are pr ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Targeted nanoparticle gene therapy for lung cancer

    SBC: SAVARA INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Project Summary A transformational NanoNucleic delivery technology is being investigated by Savara Inc. as a promising first-in-class gene therapy candidate for lung cancer. A potent lung cancer therapy with fewer sideeffects is urgently needed due to the exceptionally high rates of morbidity and mortality of this particular cancer. Gene therapy, while promisin ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Development of an Implantable Trigeminal Nerve Stimulation System for Drug Resist

    SBC: NeuroSigma, Inc.            Topic: NINDS

    DESCRIPTION (provided by applicant): Epilepsy affects three million Americans and fifty million people worldwide. Drug resistant epilepsy (DRE) affects over one third of all people with epilepsy, and may lead to unemployment, injury, and death. TrigeminalNerve Stimulation (TNS) is an emerging neuromodulation therapy for DRE, which has unique advantages over other techniques. TNS can be delivered b ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. CBT Supervisor's Toolkit: Phase II

    SBC: CBT4CBT LLC            Topic: NIAAA

    DESCRIPTION (provided by applicant): ABR's recent series of innovative randomized trials evaluating the efficacy of various strategies for training clinicians to use evidence based therapies in alcohol and drug abuse has indicated that while both in-personworkshop and computer-assisted training can impart the skills necessary to deliver Cognitive Behavioral Therapy (CBT), they are not suffici ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. High throughput tau oligomer drug screening assay for Alzheimer's disease

    SBC: OLIGOMERIX INC            Topic: NIA

    DESCRIPTION (provided by applicant): There is a very large and rapidly growing unmet need for disease-modifying drugs for Alzheimer's disease (AD) as its prevalence is increasing worldwide due to demographic shifts in the aging population. AD is the thirdmost costly disease in the US with direct costs over 200 billion annually. The proposed phase IIB program is for the continued development ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. BENEFIT

    SBC: BARRON ASSOCIATES, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): The overall goal of this multi-phase SBIR research effort is to develop a handheld fall risk assessment instrument for use by health and elder care providers. Falls occur in up to 30% of those over the age of 65 and upto 40% for people over the age of 80. Falls place each individual at risk for dangerous closed head injury and long bone fractures. The mortality ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Home Gait Assessment System

    SBC: EMPIRICAL TECHNOLOGIES CORPORATION            Topic: NIA

    DESCRIPTION (provided by applicant): Falls among the elderly, one of the most common reasons requiring medical intervention and a contributing factor in 40% of nursing home admissions, are a major health problem. Several studies have identified quantifiable gait markers that appear to distinguish between elderly fallers and non-fallers. These studies have relied on data acquired in gait-laborat ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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