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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201331 - 201340 of 207712 results
  1. New compounds to protect hearing during aminoglycoside therapy- safety study

    SBC: Oricula Therapeutics LLC            Topic: NIDCD

    DESCRIPTION (provided by applicant): Aminoglycoside antibiotics (AGs) are important for the treatment of a variety of serious infectious diseases including septicemia, complicated intra-abdominal infections, complicated urinary tract infections, and nosocomial respiratory tract infections. AGs are the mainstay of treating Pseudomonas infection in patients with cystic fibrosis and one of the best c ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Improving Articulatory Precision in Neurologically Compromised Adults Using Audio

    SBC: Bionic Sciences Inc.            Topic: NIDCD

    DESCRIPTION (provided by applicant): Improving Articulatory Precision in Neurologically Compromised Adults Using Audiovisual Biofeedback. One of the most frustrating impairments of neurological damage is the inability to communicate properly via the speechmodality due to weakness in the oral motor structures, also known as dysarthria. We propose to develop a Tongue Tracking System (TTS) that can p ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Low-Cost User-Friendly Otoacoustic Emissions Probe

    SBC: CREARE LLC            Topic: NIDCD

    DESCRIPTION (provided by applicant): This proposal responds to the NIDCD special solicitation RFA-DC-12-004 for improving access to hearing healthcare. In particular, the NIDCD is seeking solutions to lower the cost of hearing healthcare and improve accessfor underserved populations (such as the disabled and communities with limited resource access). Technologies that achieve the initiative object ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Co-Construction for AAC Devices

    SBC: INVOTEK, INC.            Topic: NIDCD

    DESCRIPTION (provided by applicant): There are approximately 4 million Americans with severe speech and physical impairments (SSPIs) who must rely on augmentative and alternative communication (AAC) systems to express themselves. People with SSPI are at asignificant disadvantage when communicating. AAC systems place heavy cognitive and physical demands on users, resulting in very slow communicatio ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. High-Capacity Li-Ion Rechargeable Battery

    SBC: Physical Optics Corporation            Topic: NIDCD

    DESCRIPTION (provided by applicant): Currently, approximately 7 million Americans use hearing aid devices, which usually use compact Zn-air batteries. These batteries are relatively inexpensive, safe to use, and easy to dispose of, but only work for approximately 1 week before needing to be replaced. Practically all other modern gadgets (cell phones, computers, etc.) now utilize rechargeable lithi ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Prevention of Children's Tympanostomy Tube Otorrhea

    SBC: O-RAY PHARMA            Topic: NIDCD

    DESCRIPTION (provided by applicant): Otitis media (infection of the middle ear space) is one of the most common diseases of childhood. Myringotomy with tympanostomy tube (TT) insertion is the most common operation performed on children in the United States. Otorrhea is the most common complication following tube insertion and can occur in up to 17% of ears receiving TT and is often associated with ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Customized nanotechnology based treatment of Oral Cancer

    SBC: PRIVO TECHNOLOGIES, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): According to the Oral Cancer (OC) Foundation, oral and pharyngeal cancer will cause 8,000 deaths this year, killing roughly one person per hour. Currently, cisplatin (CIS) is at the forefront of platinum- based chemotherapeutics for treating OC. However, its efficacy is often hindered by its significant systemic toxicity as a result of traditional bolus systemi ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Polymer Matrix for Dental Applications

    SBC: TDA RESEARCH, INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): Dental caries are the most common childhood disease in the United States. Dental sealants are materials that are applied to the pits and fissures of healthy teeth to prevent dental caries or other forms of decay. This method prevents bacteria ingress and acid dissolution and targets the portions of the tooth surface where ~90% of the decay develops. Peer-review ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Rapid Point-of-Care Salivary Diagnostic for Periodontal Health

    SBC: INNOVATIVE DIAGNOSTICS, INC.            Topic: NIDCR

    DESCRIPTION (provided by applicant): The dental profession has searched for many years for additional real time chair-side measures to provide objective measures to aid in the monitoring of periodontal health and early diagnosis of disease. Research efforts have produced solid evidence that constituents present in saliva can provide important complimentary diagnostic information, and have the po ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Glycosaminoglycans to Treat and Prevent Radiation-Induced Oral Mucositis

    SBC: GLYCOMIRA, LLC            Topic: NIDCR

    DESCRIPTION (provided by applicant): GlycoMira Therapeutics has developed safe and effective anti-inflammatory glycosaminoglycan derivatives and proposes to test the feasibility of using its lead compound to treat or prevent oral mucositis. Mucositis is acommon and debilitating complication of cancer treatment. Cancer patients undergoing radiation or chemotherapy often develop this painful inflam ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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