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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201341 - 201350 of 204843 results
  1. Piezoelectric MEMS microphones for hearing aids

    SBC: CytoVale, Inc            Topic: NCATS

    DESCRIPTION (provided by applicant): There has been increased interest in using mechanical properties of cells as label-free biomarkers for applications in basic biology and clinical diagnostics. Increased single-cell deformability has been correlated withmalignancy in cell lines and patient samples for example. In contrast to conventional molecular biomarkers a mechanical property is intrinsic to ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Developing an Improved Electrocompetent E. coli Host

    SBC: Pro-Change Behavior Systems, Inc.            Topic: NCATS

    DESCRIPTION (provided by applicant): Chronic musculoskeletal pain creates a significant public health burden. Veterans are disproportionately affected by chronic musculoskeletal pain, and in particular, chronic low back pain (CLBP). The frequency and extent of co-occurrence of pain and PTSD, pain and Traumatic Brain Injury (TBI), and all three conditions (Post-deployment Multi-symptom Disorder (PM ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Adapting wireless glucometer to boost opioid dependence medication compliance

    SBC: Ginkgo BioWorks            Topic: NCATS

    DESCRIPTION: Plant-derived secondary metabolites have proven to be a rich source of pharmaceuticals. From 1981 to 2010, over 65% of the 1355 new chemical entities introduced worldwide were natural products or natural product derivatives. The benzylisoquinoline alkaloids (BIAs) represent a diverse class of secondary metabolites (2500 known structures) with a broad range of pharmacological activiti ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Selectin targeted ultrasound contrast agents for detection of acute coronary synd

    SBC: ORPHAGEN PHARMACEUTICALS, INC.            Topic: NCATS

    DESCRIPTION (provided by applicant): Retinitis pigmentosa (RP), a hereditary disease of the retina affecting 100,000 Americans, is the major cause of blindness in adults aged 25-60. There is no approved therapy for the disease and gene therapy, while promising, is limited because of the diversity of underlying genetic mutations. The abnormal localization of rod opsin, the highly-expressed major pr ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Pancreatic Cancer:Assay for Early Detection

    SBC: H & N Instruments Inc            Topic: NCATS

    DESCRIPTION (provided by applicant): The near-term commercial opportunity targets the research market and is a set of diagnostic chips for the measurement of prospective biomarkers of early stage pancreatic cancer. The commercial availability of these chips would increase the odds for researchers in successfully identifying useful biomarkers. In addition, activated, customizable chips would be ava ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. DIVERSIFYING MICA TO CREATE TARGETED ADAPTERS TO RECRUIT AND ACTIVATE NK CELLS TO

    SBC: AvidBiotics Corp.            Topic: NCATS

    DESCRIPTION (provided by applicant): Monoclonal antibodies targeting tumor associated antigens (TAA's) have since 1997, provided safe and efficacious human cancer therapeutics. More recently, bispecific antibodies or bispecific antibody fragments that promote immunologic synapses between cells of the innate immune system and malignant cells have shown in clinical trials remarkable efficacy an ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Tumor-toxic CD47 mAb therapy for leukemia: a proof of concept study

    SBC: SIMMERSION LLC            Topic: NIAAA

    DESCRIPTION (provided by applicant): The goal of this Phase I/Phase II Fast-Track application is to develop and evaluate a simulation-based product for training student affairs staff (e.g., resident assistants [RAs], Greek life staff, campus and housing security, student conduct staff, and academic advisors) to assess and provide appropriate intervention to students who engage in risky drinking be ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Online Training and Certification for Competency in Dementia Friendly Hospital Care

    SBC: HEALTHCARE INTERACTIVE, INC.            Topic: NIA

    DESCRIPTION (provided by applicant): Alzheimer's disease and related dementias (ADRD) are an urgent healthcare challenge facing 21st Century America. In the U.S. in 2011, one person received an ADRD diagnosis every 68 seconds; by 2050, that number will beone every 33 seconds (Alzheimer's Disease Facts and Figures, 2010). ADRD are the third most costly disease sets in the U.S. In spite of ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Remote-Access Data Enclave for HRS/PSID Analysis

    SBC: ACUMEN LLC            Topic: NIA

    DESCRIPTION (provided by applicant): To enhance the utility of federally-funded surveys, Acumen-through a project entitled the Medicare/Medicaid Research Information Center (MedRIC)-has pursued adding individual-linked administrative data from the Centersfor Medicare and Medicaid Services (CMS) to supplement information in these survey data. Two prominent surveys are the Health and Retirement Sur ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Beta Amyloid Deposits Imaged with 18F-AZD4694 and Postmortem Histology

    SBC: Navidea Biopharmaceuticals, Inc.            Topic: NIA

    DESCRIPTION (provided by applicant): Navidea Biopharmaceuticals is developing 18F-AZD4694 as a diagnostic imaging agent to be used with PET scans to directly visualize beta amyloid (A ) deposits in the brains of living patients. A deposits in the brains of patients with dementia are diagnostic for Alzheimer's Disease. Al Alzheimer's Disease patients have abundant deposits of A in their ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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