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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201341 - 201350 of 204455 results
  1. Digital PCR in a microplate format: high-throughput, precise DNA quantification

    SBC: FORMULATRIX, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): Quantitative PCR (qPCR) is the current industry standard for quantification of DNA samples, and is used commonly in diagnostics and research. Digital PCR (dPCR) presents numerous advantages over qPCR such as increased precision and sensitivity and absolute quantification without comparison to standards. However, current digital PCR systems require complex workf ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. UNIVERSAL ECG SENSOR

    SBC: LOGAN RESEARCH            Topic: NHLBI

    DESCRIPTION (provided by applicant): The primary goal of long term monitoring is the Improvement of diagnostic yield. Despite the clear utility of Holter monitoring in clinical cardiology, issues of relatively low diagnostic yield, cost and inconvenience have motivated the development of ultra-portable devices referred to as ECG patch monitors. Although the gold standard for assessing cardiac rh ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Inhibitor #2 of Protein Phosphatase 2A (I2PP2A) and Asthma

    SBC: COGNOSCI INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Over 24 million Americans suffer from asthma, which has become a chronic inflammatory disease of the airways characterized by reversible airflow obstruction and bronchospasm together with symptoms of wheezing, coughing,shortness of breath, and chest tightness. Unlike chronic obstructive pulmonary disease (COPD) or emphysema, airway obstruction is usually revers ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A non-myeloablative conditioning regimen for hematopoietic stem cell transplantat

    SBC: P2D, INC            Topic: NHLBI

    Abstract Hematopoietic stem cell transplantation (HSCT) has become a standard care for the treatment of many hematologic malignancies and non-malignant diseases such as bone marrow failure and immunodeficiency syndromes. Currently, myeloablative or irradiative conditioning regimens are used for enhancing HSC engraftment in transplantation, but they are often associated with significant morbidity a ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. ACOUSTOPHORETIC TRANSFUSION TO REDUCE EMBOLIZATION IN CARDIOPULMONARY BYPASS

    SBC: Flodesign Sonics, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Retransfusion of a patient's shed blood during cardiopulmonary bypass is attractive since it reduces the need for allogeneic transfusion, minimizes cost, and decreases transfusion related morbidity. Heterologous transfusions are linked to increased long term mortality after cardiac surgery. However, brain damage after cardiac surgery with retransfusion of ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Inhaler Training Device for Asthma and COPD Patient Education

    SBC: Koronis Biomedical Technologies Corp.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Koronis Biomedical Technologies (KBT) proposes to develop an inhaler training system for respiratory educators with the goal of improving patients' use of dry powder inhalers (DPIs) and pressurized metered dose inhalers(pMDIs) appropriately. Studies have repeatedly observed that a significant proportion of inhaler users are not using their inhalers correct ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Boosting the innate immune system of the lungs to prevent and treat respiratory v

    SBC: PULMOTECT, INC            Topic: NHLBI

    7. Project Summary/Abstract Problem: Throughout the world, lower respiratory infections cause significant death and mortality. Seasonal influenza pneumonia alone causes more than 40,000 deaths a year in the U.S. Pandemic influenzas have even more impacts,with at least 50 million influenza-related deaths in 1918-9. Further, the anticipated avian- origin H5N1 influenza in human populations with its ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Low-cost production of rApoA-IM for the treatment of cardiovascular disease

    SBC: VENTRIA BIOSCIENCE            Topic: NHLBI

    DESCRIPTION (provided by applicant): Vascular diseases such as athersclerosis are the major causes of morbidity and mortality worldwide. The high density lipoprotein (HDL) particle is thought to protect the arteries from atherosclerosis by removing excesscholesterol and other lipids from the vessel wall and delivering them to the liver for elimination. The key protein component of HDL is apolipopr ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Development of TransApical to Aorta Double Lumen Cannula for a Neonate LVAD

    SBC: W-Z BIOTECH LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Left ventricular assist device (LVAD) support allows the neonate with congenital heart disease or cardiomyopathy to grow to a larger body weight that is more feasible for complex surgical correction or heart transplant.A paracorporeal LVAD, the Berlin heart ExCor, is FDA-approved for pediatric application. Although this device is outside the body, the outflow g ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Mild Hypothermia Catheter for Reperfusion Injury

    SBC: 3DT HOLDINGS, LLC            Topic: NHLBI

    ABSTRACT ST segment myocardial infarction (STEMI) is a serious acute coronary condition that affects 500,000 Americans each year and results in significant U.S. healthcare costs ( 31B/year for acute MI treatment). STEMI mortality directly relates to the extent of the total myocardial injury and even with the gold standard of reperfusion, up to 50% of the total myocardial injury can be related to ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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