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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201351 - 201360 of 207728 results
  1. ASC101 Enhancement of Regenerative Capacity of Amniotic Fluid-derived Stem Cells

    SBC: TARGAZYME, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): In the present STTR we propose to investigate two novel approaches in our exploration of the therapeutic and regenerative potential of cell-based medicine. Furthermore, we will utilize a preclinical animal model of compression syndrome (CS) that mimics the pathophysiology of multiple injuries such as crush injuries, burns, circulation blockage, fractures, hemor ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  2. Doppler Window for Low-Cost High-Performance Vascular Imaging

    SBC: ARBOR ULTRASOUND TECHNOLOGIES, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): This proposal describes a novel, low-cost, high-performance hand-held Doppler ultrasound imaging system to meet the clinical needs from simple vessel location to advanced vascular diagnostic techniques such as elasticity imaging. This research proposal integrates proven fundamental techniques with modern technology. The proposed device revisits original ultraso ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  3. Experience Success: Virtual Reality to Enhance Internet Weight Loss

    SBC: VIRTUALLY BETTER INC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Overweight and obesity are major health problems, affecting over two-thirds of US adults. Standard behavioral treatments (SBT), which are the gold standard for mild and moderate obesity, have been adapted forInternet delivery to facilitate dissemination, reduce cost, and overcome barriers to treatment. However, the weight losses obtained via Internet- ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Rational Design of New Drugs to Treat Ventricular Arrhythmias

    SBC: Elex Biotech, Inc            Topic: NHLBI

    DESCRIPTION (provided by applicant): Sudden cardiac death (SCD) is a major cause of death, responsible for greater than 300,000 adult deaths per year in the United States alone. Cardiac arrest and SCD are caused by ventricular arrhythmias, in particular ventricular fibrillation, which leads to the inability of the heart to circulate blood throughout the body. Approximately 50% of patients sufferin ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  5. Mitochondrial DNA repair agents for acute lung injury

    SBC: EXSCIEN CORPORATION            Topic: NHLBI

    DESCRIPTION (provided by applicant): Drug development for acute lung injury (ALI) has been marred by unfulfilled expectations. Perhaps best illustrating this unsatisfactory situation is the history of therapeutic strategies directed at inhibition of reactive oxygen species (ROS). While decades of laboratory and clinical studies make it clear that ROS are pathogenically important across the entire ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Development of a Surgical and Transcatheter Polymeric Heart Valve

    SBC: MEDSHAPE, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): 10.3 million Bioprosthetic heart valves (BHV) have been implanted since 1980 in the United States alone, but the solution for a durable, non-calcifying bioprosthesis still eludes us. High rates of structural failures and rapid calcificationin BHVs, has veered a gradual shift towards the development of polymeric heart valves (PHV). Biocompatible polymers are exc ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Low energy ventricular defibrillator

    SBC: CARDIALEN, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Sudden cardiac death is a major cause of death around the world, with approximately 400,000 sudden deaths per year in the United States, more than are attributed to lung cancer, breast cancer, or AIDS. It is often caused by ventricular fibrillation (VF) and ventricular tachycardia (VT). VF is the most frequent mechanism of sudden death. Implantable cardiac defi ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Platform for myocardial infarct MRI and delivery of therapeutics

    SBC: CELSENSE, INC.            Topic: NHLBI

    Myocardial infarction (MI) afflicts more than one million persons per year in the United States alone. MI results in permanent left ventricle (LV) scarring that causes diminished pump efficiency and, commonly, heart failure. Towards reduction or elimination of scarring, there is increasing interest in reparative biological materials, such as cells and proteins, that are introduced into the affecte ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Ventilation Stethoscope using Hyperpolarized Xenon

    SBC: MIRTECH INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Ventilator Induced Lung Injury (VILI) is a common cause of morbidity and sometimes mortality in critically ill patients with respiratory failure. The types of VILI include barotraumas, volutrauma, atelectrauma, and biotrauma. Thus ventilator setting is a delicate balance between achieving sufficient ventilation but avoiding excessive pressure and overdistensio ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  10. COA360H: A Tool to Assess Accreditation of Healthcare Organizations

    SBC: DayStar Research            Topic: NIMHD

    DESCRIPTION (provided by applicant): This Phase I STTR application seeks support for research to enhance the commercial viability of a tool to assess the cultural competence of health care organizations. The Cultural-competency Organizational Assessment - 360 (COA360) is a web-based tool to measure the cultural competence of healthcare organizations. Major changes in the regulatory environment ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
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