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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201361 - 201370 of 207725 results
  1. Magnetic Flow Sorter for Pancreatic Islet Isolation

    SBC: TECHSHOT, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Techshot, Inc. has successfully completed SBIR Phase I and Phase II research demonstrating that magnetically labeled porcine islets of Langerhans can be isolated from contaminating exocrine tissue by flow sorting usinga quadrupole magnetic separator ( Quadrasep ) designed for that purpose. Magnetically sorted islets are superior in morphology and physiology to ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Mobile Motivation for Health Promotion Among Adolescents

    SBC: BodiMojo, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): This Phase II SBIR application proposes the development and testing of a theory-based health promotion mobile phone application, BodiMojo, for adolescents (ages 13-18). The product is designed to: (1) promote wellness,healthy eating and physical activity in adolescents through a mobile program that can be accessed via any cell phone or wireless device; and (2) ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Hollow Fiber Catheter for Drug Delivery into the Prostate

    SBC: TWIN STAR MEDICAL            Topic: NIDDK

    DESCRIPTION (provided by applicant): The significance of the proposed research is based on the growing demand for healthcare resources to treat and manage prostatic disease, particularly benign prostatic hyperplasia (BPH) and cancer. Both the incidence andcost of treatment for BPH, and its complications, are growing rapidly with the aging U.S. population; prostate cancer is the second-leading caus ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Biased Agonism In GPCR Drug Discovery: Application To Somatostatin Agonists

    SBC: Crinetics Pharmaceuticals, Inc.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Neuropeptide somatostatin analogs are important therapeutics for the treatment of hormone secreting tumors with annual sales of ~ 1.7B. However, the currently available peptide depots are effective in only half the patients with growth hormone secreting tumors, and patients with carcinoids can rapidly become resistant to these drugs. Somatostatin analogs act by ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Prebiotic Fiber as Targeted Dietary Management of Irritable Bowel Syndrome

    SBC: NUTRABIOTIX, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): The objective of this Phase II SBIR application is to test NTX-1 fiber in patients with constipation-predominant IBS (IBS-C) and determine if it can reduce symptoms, beneficially modify gut microbiota composition, and improve gut milieu in these patients. Our hypothesis for the Phase II study is that NTX-1 fiber is better tolerated (i.e. has less side effects) ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Continuous Monitoring of Glycemic Oscillations in Interstitial Fluid

    SBC: Ultradian Diagnostics, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): In Phase 1, measuring and characterizing glucose oscillations in yeast cells immobilized on the surface of a glucose sensor was completed. Using this as a model, it was postulated that within the subcutaneous environment, cells (e.g., fibroblasts, adipocytes) would be in close proximity to the surface of the glucose sensor thereby mimicking the in vitro environ ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Development of a human hepatocyte predictive pharmacology and toxicology system.

    SBC: HemoShear Therapeutics, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): There is a critical need to improve the accuracy of preclinical drug efficacy and toxicity screening and testing through the development of human hepatocyte (liver) in vitro culture systems that more effectively mimic the human in vivo environment. HemoShear is a biotechnology research company that utilizes patented methodologies to restore in vivo responsivene ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Commercialization of Tissue Lined Stent Graft for Dialysis Access Failure

    SBC: Peritec biosciences Ltd            Topic: NIDDK

    DESCRIPTION (provided by applicant): An estimated 11.5 percent of adults (approx 23 million people) suffer from chronic kidney disease. Among people suffering from ESRD, the mortality is approximately 163.8 deaths per 1,000 patient years. Hemodialysis is the leading treatment for more than 341,000 patients in the United States with end-stage renal disease (ESRD), or kidney failure, which can be ca ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Anti-CD47 mAb Therapy to Improve Kidney Transplantation

    SBC: VASCULOX, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Organ transplantation is a lifesaving option for those with end stage renal disease. In spite of many improvements in organ procurement, transplant procedures and immune suppression, the damage done by ischemia-reperfusion injury (IRI) remains problematic, leading to primary graft nonfunctional, delayed graft function and graft failure. The critical shortage of ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Dramatic Improvements to the Doubly Labeled Water Technique by Measurement of 17O

    SBC: Los Gatos Research            Topic: NIDDK

    DESCRIPTION (provided by applicant): The high prevalence of obesity in the US is a major public health concern, as overweight and obese individuals are at increased risk for many chronic diseases. Obesity stems from an imbalance between total caloric consumption and total energy expenditure (TEE), therefore accurate measurements of TEE play a pivotal role in understanding and ultimately reversing ...

    SBIR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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