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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201371 - 201380 of 207728 results
  1. Early Detection of Pancreatic Cancer Using Ice COLD-PCR

    SBC: TRANSGENOMIC, INC.            Topic: NCATS

    DESCRIPTION (provided by applicant): Ninety percent of all pancreatic cancers are pancreatic ductal adenocarcinoma (PDAC). PDAC diagnosis is difficult, usually occurring in the late stages of disease. Patients with these advanced tumors typically respondpoorly to therapy. Post diagnosis, median survival is 6 months and the five-year survival rate is lt 4%. Five-year survival is lt 1% for those wi ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  2. scribIT: a System for Freehand Production, Editing, Communication and Reproductio

    SBC: E.A.S.Y. LLC            Topic: NCATS

    DESCRIPTION (provided by applicant): The ultimate goal of this project is to market a electromechanical and software system for Blind and Low Vision (B/LV) individuals that will enable creation, communication and reproduction of freehand drawings. In school, at home and in the workplace, virtually everyone needs to be able to produce a wide variety of freehand sketches, diagrams, driving direction ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  3. Automated image-based biomarker computation tools for diabetic retinopathy

    SBC: EYENUK, INC.            Topic: NCATS

    DESCRIPTION (provided by applicant): In this STTR project, we present EyeMark, a set of tools for automated computation of biomarkers for diabetic retinopathy using retinal image photographs. Specifically, we will develop tools for computation of microaneurysm (MA) appearance and disappearance rates (jointly known as turnover rates) for use as a biomarker in monitoring progression of diabetic reti ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  4. The Bumps, a device for rapid, non invasive quantification of touch sensation

    SBC: Neuro Devices, Inc.            Topic: NCATS

    DESCRIPTION (provided by applicant): This application describes an elegantly simple, pocket size device, called the Bumps that rapidly quantifies the important sensation of touch on the fingers in micrometer ( m) units. This high sensitivity differentiates the small variations f touch sensation that exist between healthy subjects and can detect minor reduction of touch sensation in fingers of ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  5. Human monoclonal antibodies for prevention of S. aureus infections

    SBC: SORRENTO THERAPEUTICS, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): Using mouse monoclonal antibodies (mAbs) raised against the mediators of quorum sensing (QS), the Auto-Inducing Peptides (AIPs), researchers at The Scripps Research Institute (TSRI) have demonstrated that S. aureus infections can be prevented in animal challenge models. This approach, known as quorum quenching (QQ) is unique in at least two significant ways: fi ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Nanocytological Fecal Assessment to Personalize Colonoscopic Surveillance

    SBC: NANOCYTOMICS LLC            Topic: NCI

    DESCRIPTION (provided by applicant): The clinical impact of the 5 million annual surveillance colonoscopies (follow up of previous neoplasia) is remarkably low (gt90% without significant neoplasia). Juxtaposed with this is the alarmingly frequent occurrence of colorectal cancers (CRCs) in between colonoscopies (interval cancers), especially in the proximal colon. The medico-legal and clinical ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Investigation of a nanoparticle albumin-bound mTOR inhibitor, nab-rapamycin for t

    SBC: AADI, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): In 2011, it is estimated that there will be 69,250 new bladder cancer cases in the United States, resulting in 14,990 deaths. Most cases (70-80%) present with nonmuscle-invasive bladder cancer (NMIBC) [1, 2]. Intravesical bacillus Calmette-Guerin (BCG), which elicits a nonspecific local immune response, is considered the standard first-line treatment. However, ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. Transdermal Naltrexone for Opiate Addiction and Alcoholism

    SBC: ALLTRANZ, INC.            Topic: NIDA

    DESCRIPTION (provided by applicant): According to the National Survey of Drug Use and Health (NSDUH) of 2008, 7.2 million Americans are in need of treatment for Substance-Related Disorders (SRDs), and a large proportion of those need treatment for opiate pain reliever, heroin, and alcohol addiction. Naltrexone (NTX), an opioid antagonist, is currently used in oral tablet form to help maintain opio ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Alafair Biosciences develops cross-linked polysaccharide hydrogel films to addres

    SBC: ALAFAIR BIOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The goal of this STTR project is to develop a pre-formed, naturally-based hydrogel postoperative adhesion barrier with improved handling characteristics, laparoscopic deliverability, and consistent efficacy. Our technology is based on a novel, patented process that imparts exceptional elasticity and toughness on normally brittle, weak materials. Postoperative a ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  10. IYG-Family: Beyond the talk to effective pregnancy, STI, and HIV prevention

    SBC: Radiant Creative Group, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): The goal of this 3 year Fast-Track STTR is to develop and evaluate a home-based intervention ('it's Your Game- Family') to provide age-appropriate sexual health life skills education and training for children (11-14 years) and to enhance parents' skills and self-confidence in support of this training. IYG-Family (IYG-F) will be an on-line g ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
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