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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201371 - 201380 of 204843 results
  1. Multiplexed Assays for Improving Rheumatoid Arthritis Diagnostics

    SBC: PROGNOSYS BIOSCIENCES, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): There is a need for multiplexed assay technologies that enable diagnostics and detailed characterization of rheumatoid arthritis. In this project we plan to discover new rheumatoid arthritis biomarkers and implement them in a panel of multiplexed assays. We propose a novel approach that offers significant advances over existing methods, including the ability to ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Advanced Micro-patterned Wound Dressings for Enhanced Epithelialization

    SBC: Sharklet Technologies Inc.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Nearly 12 million wounds are treated in U.S. emergency departments every year. Skin wounds such as severe burns, large trauma wounds, or non-healing/chronic wounds that are too extensive or complex to close by natural healing are often reconstructed using autologous skin grafts. Although autologous skin grafts are currently the gold standard in complex wound re ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Coincident light/ultrasound therapy to treat acne vulgaris and atopic dermatitis

    SBC: SONIC TECH, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Sonic Tech Inc. is developing a unique energy-based therapy called CLENS (Coincident Light Energy and Non-focused ultraSound). Using two well-established clinical energy sources in a novel way, the technology is intended to treat dermal diseases caused by biofilms, a bacterially generated slime layer. Biofilms shield bacteria from attack by both antibiotics an ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Detection of Botanicals and Adulterants Using the Novel DNA-Based Technology Seq

    SBC: AUTHENTECHNOLOGIES, LLC            Topic: NCCIH

    DESCRIPTION (provided by applicant): From cosmetics, to supplements and pharmaceuticals- natural products using a wide-array of botanicals play an important role in our health and wellbeing. However, deceitful adulteration poses a great risk to the naturalproducts industry and the safety of its consumers; there are a number of well-known cases involving substitution by toxic species that have led ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. BAC Sudoku Sequencing Paradigm to Accelerate Metagenomic Natural Product Chemistr

    SBC: LUCIGEN CORPORATION            Topic: NCCIH

    DESCRIPTION (provided by applicant): There is societal need for new compounds in our arsenal of defenses against microbial pathogens, many of which are increasingly resistant to existing therapeutics. The best possible source for new antimicrobial compounds with potentially novel mechanisms of action is within natural environments, particularly soils, which have the greatest diversity of microbial ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Spiral Countercurrent Chromatography for High-throughput Natural Product Purifica

    SBC: CC BIOTECH LLC            Topic: NCCIH

    DESCRIPTION (provided by applicant): Recent advances in countercurrent chromatography (CCC) have created novel spiral-design separation columns that hold a very high stationary phase of all the solvent systems, such that now all molecules of any size and water solubility can be successfully separated in high-speed countercurrent chromatography. With spiral CCC there is inherent versatility, more t ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Ultrahigh-throughput Identification of Molecular Targets of Natural Products

    SBC: NEWOMICS INC.            Topic: NCCIH

    DESCRIPTION (provided by applicant): Natural products are rich sources for potential drugs. To accelerate drug discovery from natural products, it is imperative to identify their molecular targets, and mechanistically elucidate their bioavailability, toxicity, and therapeutic effects. However, there remain several challenges in the field. Among them, there is currently no technical platform that c ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Development of SFS Fractionators

    SBC: APHIOS CORPORATION            Topic: NCCIH

    DESCRIPTION (provided by applicant): The screening of a complex mixture of analytes is not always successful in sensitive screens for specific activities. Often, specific activities are masked by interfering compounds or false positives are given by ubiquitous compounds that interact with all screens. This problem can be resolved by purification of the analytes. Such an approach is not only cost-p ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Increased bioavailability of polyphenols through bacterial metabolism

    SBC: AGRO BIOSCIENCES, INC.            Topic: NCCIH

    DESCRIPTION (provided by applicant): Numerous preclinical studies have demonstrated multiple health benefits including anti- inflammatory, antioxidant, and chemopreventive effects of dietary polyphenols. These compounds are abundant in plants and have added to the health benefits of many fruits, such as raspberries, pomegranates, and strawberries. As aging population in the U.S. and other develope ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Real-time qPCR assay for detection of ALT associated telomeric C-circle DNA in bl

    SBC: Capital Biosciences, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): The overall goal of the proposed project is to investigate the feasibility of employing real-time qPCR method for detection of telomeric C-circle DNA in peripheral blood of patients with cancers that utilize Alternative Lengthening of Telomeres (ALT) as their Telomere length Maintenance Mechanism (TMM). Telomeric C-Circle DNA has been demonstrated to be specif ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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