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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201371 - 201380 of 207699 results
  1. Use of Direct Filtration on the Influent to Floating Bead Filters and Treatment of Waste Discharge with Coagulation Aids for Suspended Solid

    SBC: AQUACULTURE SYSTEMS TECHNOLOGIES, L.L.C.            Topic: 87

    As fish species with greater sensitivity to water quality are cultured in recirculating aquaculture systems (RAS), it becomes vital to improve fine solids capture. Additionally, phosphorous levels in the discharge from RAS are often high (per EPA guidelines and regulations) and can lead to eutrophication of receiving waters. This project has the potential to improve PBF performance in both respect ...

    SBIR Phase I 2011 Department of Agriculture
  2. USE OF DNA PROBES FOR THE DETECTION OF LYME DISEASE

    SBC: SERACARE LIFE SCIENCES, INC.            Topic: N/A

    THE TREATMENT OF LYME DISEASE COULD BE GREATLY ENHANCED IF IT WERE POSSIBLE TO DETECT THE LYME DISEASE SPIROCHETE DIRECTLY IN BLOOD WITH A HIGHLY SENSITIVE TEST. IT IS PLANNED TO DEVELOP A TEST WHERE A REGION OF THE BORRELIA BURGDORFERI OSPA GENE IS AMPLIFIED USING THE POLYMERASE CHAIN REACTION (PCR) TO OBTAIN THE NECESSARY SENSITIVITY. THE AMPLIFIED PRODUCT WILL BE DETECTED INITIALLY BY SOUTHERNB ...

    SBIR Phase I 1990 Department of Health and Human Services
  3. Use of DNATrax and high fidelity computational methods to model transport of contaminants in urban environments

    SBC: SAFETRACES, INC            Topic: NIEHS

    PROJECT SUMMARY ! The abundance of airborne micron sized pollutant correlates with the prevalence and severity of respiratory diseaseswhich represents therd leading cause of death in the United States and have an economical cost of tens of billions of dollars per yearGrowing concerns on the possibility of terrorist attacks have motivated efforts in preparing for and responding to airborne releases ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  4. USE OF DNATrax TO MODEL THE TRANSPORT OF PARTICULATE MATTER IN URBAN ENVIRONMENTS

    SBC: DNATREK, LLC            Topic: NIEHS

    DESCRIPTION provided by applicant Science based strategies for quantifying and mitigating the impact of anthropogenic emissions on public health are essential for the sustainability of cities Similar strategies can also be used to develop and assess the effectiveness of a national defense system against terrorist attacks with airborne biological agents and protect against the spread of airborn ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  5. Use of Domain/IP Resolver in Lieu of Traditional Username/Password Authentication

    SBC: Information International Associates, Inc.            Topic: 41

    DOE currently operates an International Databases for sixteen countries. Currently, access is controlled by checking the IP address and/or username/password of registered users. Some countries would like to permit any citizen in their country to access the data, while other countries would like to restrict access to a set of specific registered citizens. This project will develop technology for ...

    SBIR Phase I 2007 Department of Energy
  6. Use of Dose Safety Controller (DSC) Artificial Pancreas in Subjects with Hypoglycemia Unawareness

    SBC: DOSE SAFETY INC            Topic: 200

    DESCRIPTION provided by applicant The objective of this project is to demonstrate that the Dose Safety Controller DSC improves the health and lives of persons with Type diabetes T D that have become unaware of hypoglycemia This research aims to show that an artificial pancreas AP device using the DSC will safely andamp effectively control blood glucose for T D patients with hypogly ...

    SBIR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Use Of Dynamic Distortion To Predict And Alleviate Loss Of Control

    SBC: Systems Technology, Inc.            Topic: A103

    Improvements to aviation safety will be made by the development and validation of means to alleviate, alert, and inhibit loss of control associated with unfavorable pilot-vehicle interactions. These unfavorable interactions are caused in part by deficiencies, called ?dynamic distortion,? in the manual flight control system. Many sources of dynamic distortion such as friction, preload, and backlas ...

    SBIR Phase I 2004 National Aeronautics and Space Administration
  8. Use Of Dynamic Distortion To Predict And Alleviate Loss Of Control

    SBC: Systems Technology, Inc.            Topic: A103

    The intent of this project is to develop and validate means to alert, constrain and thereby alleviate loss of control (LOC) associated with unfavorable pilot-vehicle systems (PVS) interactions present in high gain, closed-loop PVS operations. While the effective aircraft dynamic properties involved in these events have been extensively studied and understood, similar scrutiny has not been paid to ...

    SBIR Phase II 2005 National Aeronautics and Space Administration
  9. USE OF DYRK1A/B KINASE INHIBITORS FOR THE TREATMENT OF LIVER DISEASES

    SBC: Avanti Biosciences Inc            Topic: 300

    PROJECT SUMMARYNonalcoholic fatty liver disease (NAFLD) is the most prevalent chronic liver disease. One-fourth of the adult population suffers from NAFLD worldwide. Nonalcoholic steatohepatitis (NASH), the aggressive form of NAFLD, can progress to cirrhosis and hepatocellular cancer (HCC) and is rapidly becoming the leading cause of end-stage liver disease and liver transplantation. Liver fibrosi ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  10. Use of ECIS Technology for Real-Time Non-Invasive Identification of Partially and/or Fully Differentiated Cells for Regenerative Medicine

    SBC: Noveome Biotherapeutics, Inc.            Topic: OSD11H14

    The Electric cell-substrate impedance sensing (ECIS) technology provides an excellent miniaturized platform on which to design and execute non-invasive and label-free specialized biological assays to continuously monitor cellular parameters such as viability, adhesion, and proliferation in a high throughput way. It records electrical impedance of cells grown on microelectrodes integrated into the ...

    SBIR Phase I 2012 Department of DefenseDefense Health Agency
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