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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201381 - 201390 of 207728 results
  1. Internet-Based Distributed Quantitative 4D Analysis of Aortic MR/MDCT Images

    SBC: MEDICAL IMAGING APPLICATIONS, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Aortic aneurysms and dissections are a cause of frequently preventable death for over 13,000 people annually in the US alone. Many more patients live under a constant threat of a catastrophic aortic event from atherosclerotic or congenital causes. Therefore, early and comprehensive diagnosis of morphological or dynamic changes in the aorta is of great importanc ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  2. Targeted Nanoparticles of Bismuth Organo Complexes for Spectral CT Imaging of Cor

    SBC: Ocean Nanotech LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Chest pain in patients presenting to the emergency department (ED) present a clinical dilemma: transfer for emergent coronary revascularization, admit overnight for cardiac telemetry and stress testing, or discharge home with medical follow-up. In this proposal, we hypothesize that a novel thrombus-specific Spectral Computed Tomography (Multicolored CT) nanopar ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  3. Optogenetic Multiparametric Assay for HT Cardiotoxicity Testing

    SBC: VALA SCIENCES, INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Monitoring physiology of individual cardiomyocytes in high throughput has not been reported. The inability to perform high throughput physiological measurements limits many basic and applied studies, including the use of stem cell derived cardiomycoytes in cardiotoxicity testing. Current automated cardiotoxicity tests have poor predictive value because they use ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  4. Development of flow and vascular quantification software for the assessment of MR

    SBC: Magnetic Resonance Innovations, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): There has been a huge increase in demand for comprehensive quantitative analysis of neurovascular imaging data produced in the clinical setting for diseases such as multiple sclerosis, traumatic brain injury, stroke anddementia. Our objective in this project is to design and develop advanced image processing software that can rapidly and accurately analyze such ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  5. Development of a Biochemical Diagnosis for Creutzfeldt-Jakob disease

    SBC: Amprion, Inc.            Topic: NINDS

    DESCRIPTION (provided by applicant): Human prion diseases are infectious and invariably fatal forms of neurodegenerative diseases, including sporadic Creutzfeldt-Jakob disease (sCJD), the most common form, and variant CJD (vCJD) which is associated to consumption of cattle meat infected by bovine spongiform encephalopathy. Currently there is not sensitive, objective and non-invasive biochemical di ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. Using Technology to Deliver Evidence-Based Interventions to Alzheimer Caregivers

    SBC: UPSTAIRS SOLUTIONS, LLC            Topic: NIA

    DESCRIPTION (provided by applicant): Family caregiving is a growing public health concern and caregivers of persons with Alzheimer's disease and other dementias need appropriate, timely, and ongoing training to successfully meet their caregiving responsibilities. Well-designed interventions can significantly reduce risks to caregivers' mental health and improve care recipient outcomes. H ...

    STTR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  7. Phase II STTR: Portable Device for Telecare Monitoring of Elderly People

    SBC: BIOSENSICS LLC            Topic: NIA

    DESCRIPTION (provided by applicant): We propose to address two important public health quality of life concerns - fall prevention and frailty in older adults by developing an accurate wearable sensor technology that more accurately characterizes physical activity, risk of falling and early indicators of frailty. In Phase I of this STTR project, we developed a unique platform (PAMSysTM: Physical Ac ...

    STTR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  8. A novel vaccine: botulinum neurotoxin subunit on a viral carrier.

    SBC: MOLECULAR TARGETING TECHNOLOGIES, INC.            Topic: NIAID

    DESCRIPTION (provided by applicant): According to the NIAID fact sheet on Botulism, the extreme toxicity of botulinum neurotoxins (BoNT) and the ease of production, transport, and delivery make this an agent of extreme bioterrorism concern. Nonetheless, although there are major vaccine development initiatives ongoing, there currently is no approved Botulinum toxin vaccine available. Advances i ...

    STTR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Delivery system development for a reservoir targeted Lyme disease vaccine

    SBC: FoodSource Lure Corporation            Topic: NIAID

    DESCRIPTION (provided by applicant): The incidence and geographic distribution of Lyme disease in the U.S. has increased steadily since its first description in 1977. Efforts to stem the spread of the disease through controlling the population of its tickvector and/or the mouse reservoirs of the disease have met with only limited success. The only approved human vaccine to protect against Lyme di ...

    STTR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  10. GalT-KO Pigs Expressing Primate CD47 to Facilitate Organ Xenografts

    SBC: MINITUBE OF AMERICA            Topic: NIAID

    DESCRIPTION (provided by applicant): Xenotransplantation with pig organs offers the best near term hope for satisfying the limitation imposed by shortage of human organs. This research project is directed toward producing as a product a genetically modified pig that will be the best potential donor for xenotransplants to humans. Although hyperacute rejection of pig organs in primate recipients ...

    STTR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
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