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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201381 - 201390 of 204843 results
  1. Neurorestorative Strategy for Diabetic Peripheral Neuropathy

    SBC: 3-C Institute for Social Development, Inc.            Topic: NICHD

    DESCRIPTION (provided by applicant): Early childhood research indicates that school readiness is a key determinant of a successful transition to school. Between 9.5% and 14.2% of young children experience social-emotional problems that negatively impact school-readiness, and nearly half of children with significant behavior problems at school entry demonstrate more serious behavioral and academic ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Clade C-specific HIV assay to distinguish true infection from vaccine-induced ser

    SBC: THEYFIT, LLC            Topic: NICHD

    DESCRIPTION (provided by applicant): A policy statement by the World Health Organization notes that, the male latex condom is the single, most efficient, available technology to reduce the transmission of HIV and other sexually transmitted infections. Unfortunately, despite decades of condom promotion efforts, condoms usage rates remain disappointingly low. Between one-third and one-half of men ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Scientific Basis of Iodine-Fluoride Varnish in Preventing Dental Caries

    SBC: SYNTHOMICS, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The goal of this project is to develop a DNA synthesizer capable of synthesizing synthetic DNA, called oligonucleotides, a dramatically lower cost than competing technologies. Specifically, we will synthesize oligos ina sample plate that can hold up to 1,536 unique oligonucleotides instead of the industry standard 96 oligonucleotides. By miniaturizing the well ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Improved Library Preparation Workflows for Next Generation Sequencing

    SBC: TRILINK BIOTECHNOLOGIES, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): Next generation sequencing (NGS) technologies are a rapidly developing area, with the ability to produce gigabases of sequencing data at reduced costs. While NGS is best recognized for genomic DNA sequencing (DNA-Seq),there is a significant body of work to expand the breadth of sample types being studied. RNA deep sequencing (RNA-Seq) is a well-developed segmen ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Accurate, long read length, whole human genome sequencing under 100

    SBC: ELECTRONIC BIOSCIENCES, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The aim of this project is to investigate a simple method for slowing down the rate of electrophoretic translocation of DNA through a nanopore. Unique modulations of current across nanopores produced by individual basesduring such translocation forms the basis of DNA nanopore sequencing. The nanopore method requires very simple sample preparation with potential ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Automated genome-phenome analysis

    SBC: SimulConsult, Inc.            Topic: NHGRI

    DESCRIPTION (provided by applicant): Automated genome-phenome analysis The declining cost of whole exome sequencing (WES) is nearing the point at which the spread of WES into clinical practice will be limited largely by the cost of interpreting the resultsand comparing the to the patient's clinical findings. This project tests the feasibility of reducing this interpretaton cost by pairing aut ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. A kit to detect and count individual DNA molecules of interest

    SBC: CELLULAR RESEARCH, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): Accurate measurement of nucleic acid concentrations is essential in many areas of genome research and its application to human health. Sensitive, precise and reliable quantitative nucleic acid tests are increasingly necessary in many important public health problems, including cancer, infectious disease and prenatal diagnostics. However, there is currently a la ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. A kit for single cell gene expression analysis

    SBC: CELLULAR RESEARCH, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The study of gene expression is fundamental to our understanding of how cells function. We propose to develop a highly sensitive and precise method to measure global gene expression in single cells. Our novel method issimple, yet is capable of accurately counting individual transcripts across all genes expressed within a single cell. The measurements obtained a ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Twist-Biosensor: Novel single molecule microarray technology for DNA genotyping

    SBC: SCANOGEN INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The availability of human genomic information and its variability is allowing researchers to identify the genetic variations responsible for patients' different responses to treatment.1-3 In order to deliver the benefits of personalized medicine to the clinical practice, it is necessary to have accurate genotyping techniques capable of determining multiple ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. High Pressure Sample Preparation Instrumentation for DNA Sequencing.

    SBC: PRESSURE BIOSCIENCES, INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): Encouraged by NIH's challenge to enable the 1000 genome, current developments in massively parallel sequencing (MPS) continue to increase throughput and reduce the cost of whole-genome sequencing. Unfortunately, the corresponding sample preparation methodologies now lag behind in throughput and DNA quality, thus slowing the pace of discovery and adoption ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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