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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201391 - 201400 of 205043 results
  1. Real Time Oxygen Monitoring for Tissue Health Peripheral Artery Disease Application

    SBC: PROFUSA, INC.            Topic: NHLBI

    DESCRIPTION provided by applicant Continuous biochemical monitoring has the power to change currently accepted standards of care shifting the emphasis from treating illness to maintaining health Point in time snapshots of a patientandapos s health can miss critical fluctuations or early warning signs that might warrant early interventions or changes in disease treatment and management PROFUS ...

    STTR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
  2. Fluorescence Enhanced Photothermal Infrared Spectroscopy (FE-PTIR)- breakthrough for simultaneous fluorescence microscopy and sub-micron IR spectroscopy

    SBC: PHOTOTHERMAL SPECTROSCOPY CORP.            Topic: 400

    1 This Phase II project aims to develop and commercialize Fluorescence Enhanced Photothermal Infrared (FE-PTIR) imaging2 and spectroscopy. The proposed FE-PTIR will use fluorescence microscopy to map the distribution of fluorescently labeled3 regions of cells and tissue and then provide chemical structural analysis of the labeled regions using photothermal infrared4 spectroscopy. Fluorescence micr ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Therapy of Pulmonary Diseases with Peptide-Oligonucleotide Conjugates and Small Molecule Enhancing Compounds

    SBC: Initos Pharmaceuticals LLC            Topic: 100

    ABSTRACT Antisense oligonucleotides (ASOs), siRNA and splice switching oligonucleotides (SSOs) all have immense potential as therapeutic agents, potential that is now being validated as oligonucleotides enter the clinic. SSOs in particular possess great therapeutic flexibility since they can be used to increase, decrease or alter the pattern of mRNA expression. However, progress in oligonucleotide ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  4. An immunotherapeutic to prevent gonorrhea

    SBC: Planet Biotechnology Incorporated            Topic: NIAID

    Antimicrobial resistance is a major public health problem worldwide. Neisseria gonorrhoeae (Ng), the causative agent of the sexually transmitted infection gonorrhea, has become multidrug-resistant and has achieved “superbug” status. In addition, between 6% and 12% of women successfully treated for gonorrhea are re-infected within three months. Novel therapeutics against Ng are urgently needed. ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  5. A scalable superconducting dual-shielded fetal magnetocardiography system

    SBC: Applied Physics Systems, Inc.            Topic: NHLBI

    PROJECT SUMMARYThere are 26,000 unexplained fetal deaths in the US and over 4 million worldwide annually. Fetal cardiac arrythmia is a significant cause of fetal demise and is diagnosed in 1-3% pregnancies. While most occurrences are benign, serious arrhythmia can lead to life-threatening complications if undiagnosed or untreated. Echocardiography and cardiotocography have been widely used to asse ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Lithium Oxyhalide Battery Separator Material

    SBC: INNOSENSE CORPORATION            Topic: MDA15027

    InnoSense LLC (ISL) is further-engineering an all-ceramic, rollable separator (CeRollS™) component for use in lithium oxyhalide batteries (LOHBs). Our goal is to render this flexible ceramic separator robust for withstanding high pressure, shock and vibration. This separator will also overcome performance issues associated with deleterious reactions between existing polymer based separators and ...

    SBIR Phase II 2022 Department of DefenseMissile Defense Agency
  7. TrachAlarm: A novel, low-cost accessory to automatically detect and alert caregivers to tracheostomy tube decannulation

    SBC: INNOVATIONS UNLIMITED LLC            Topic: 600

    Tracheostomy provides a critical, life-supporting function for over 6.5 million individuals in the U.S. with over 110,000 new procedures each year. The TrachAlarm is a novel, low-cost accessory to automatically detect and alert caregivers when a tracheostomy tube is accidentally removed from a patient. It provides a low-cost, accessible solution for tracheostomy patients and caregivers by utilizin ...

    SBIR Phase II 2020 Department of Health and Human ServicesNational Institutes of Health
  8. Multimode Super-Resolution Sensor Technology

    SBC: CYAN SYSTEMS, INC.            Topic: SB092012

    Cyan Systems has designed a new Multimode Superresolution Sensor Technology (MSST). The MSST is a centerpiece of new technology allowing improved resolution over existing sensors, increased range of target ID, improved Noise Equivalent Power (NEP). The MSST is designed to revolutionize the resolution and sensitivity of IR sensors by oversampling the image and using biological inspired small pixel ...

    SBIR Phase II 2011 Department of DefenseDefense Advanced Research Projects Agency
  9. Application of the Nanotrap Technology Platform for Immunome Biomarker Preservation and Monitoring

    SBC: CERES NANOSCIENCES            Topic: SB112005

    Immune marker panel tests can provide significant information for understanding and addressing many areas of health and wellness and disease conditions. However, conducting large clinical studies to identify the significance of panel based biomarkers has been hampered primarily by the logistics of acquiring quality samples from clinical subjects and extracting and measuring the valuable markers on ...

    SBIR Phase II 2016 Department of DefenseDefense Advanced Research Projects Agency
  10. High-specificity affinity reagents for N-glycosylation site mapping and glycomics

    SBC: GLYCOSENSORS AND DIAGNOSTICS, LLC            Topic: 300

    DESCRIPTION Glycans have several distinct properties that make them excellent targets for disease biomarkers Firstly the location of the glycans on the cell surface makes them the first point of contact of cellular interactions and thus crucial in the control of normal metabolic processes Cell surface molecules are also strategically exposed for surveillance by the immune system allowing for ...

    STTR Phase II 2013 Department of Health and Human ServicesNational Institutes of Health
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