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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201391 - 201400 of 204843 results
  1. Aspirin-PC for Chemoprevention of Colorectal Cancer

    SBC: Biospyder Technologies, Inc.            Topic: NHGRI

    DESCRIPTION (provided by applicant): This proposed Phase I SBIR project will transfer RASL-Seq, a targeted sequencing technology developed in academia, to a small business, 255Xpress, Inc., and demonstrate feasibility for its commercialization as a platform for drug discovery and high throughput screening (HTS). The technology detects hundreds of RNA targets at once in cell lysates, using oligo li ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Quit IT: Development of a Web-based 3D Coping Skills Game to Increase Self-Effic

    SBC: Eve Biomedical, Inc.            Topic: NHGRI

    DESCRIPTION (provided by applicant): The long-term goal of the proposed research is the design and construction of a DNA sequencing system that can sequence the whole human genome under 100 including sample preparation and with the cost of goods of the system well under 10,000. The system developed under the proposed research is at least an order of magnitude in cost better than the target of th ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Novel Full-Color High Frame Rate 3D Projector for Multiview 3D Displays

    SBC: WISEGENE LLC            Topic: NHGRI

    DESCRIPTION (provided by applicant): 5-Hydroxymethylcytosine (5hmC) is a newly identified base modification in mammalian genomic DNA that can accumulate to relatively high levels in certain tissues or cells. Current sequencing methods cannot differentiate5mC from 5hmC, however. Therefore, the immediate challenge is to develop robust methods to ascertain the positions of 5hmC within the mammalian g ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. RVC- Polymer Plate for improved biomedical analyses by tissue imaging MALDI-TOF

    SBC: LUCIGEN CORPORATION            Topic: NHGRI

    DESCRIPTION (provided by applicant): The genetic basis of disease remains a significant research problem, impacting the fields of cancer biology, neurology, cardiology, development, and even microbiology, as recently realized by the Human Microbiome Project. Determination of the genomic sequence underlying observed phenotypes is now widespread. Genomic sequencing is becoming faster and cheaper, al ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Anatomic 3D synthetic tissue printer

    SBC: ONTERA INC.            Topic: NHGRI

    DESCRIPTION (provided by applicant): Nanopores are emerging technologies that offer the prospect of long-read (gt100 kb) next-generation sequencing without the need for sample amplification. Such technology can complement existing short-read and high throughput sequencing platforms to reduce errors in de novo genome assembly and structural variant analysis, or entirely replace this technology if c ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Establishing a neuroprotection model in the nonhuman primate to support translati

    SBC: INSILIXA, INC.            Topic: NHGRI

    CMOS-Integrated Fluorescence Biochip Arrays Abstract Array technologies have been responsible for a multitude of discoveries in genomics and proteomics. However, they require sophisticated and highly accurate instrumentation. Today, the bulkiness, cost, and complexity of array readers have become barriers to their adoption in point-of-care (PoC) applications. There is thus a huge demand for rugge ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Novel Mucolytic Agents

    SBC: Parion Sciences, Inc.            Topic: NHLBI

    DESCRIPTION (provided by applicant): Mucus transport is the fundamental defense of the airways against inhaled particulates/infectious agents. Abnormalities in the mucus transport system characterize a complex of muco-obstructive airway diseases, such as cystic fibrosis (CF) and chronic bronchitis (CB). CB associated with CF affects 30,000 Americans, and the CB associated with environmental causes ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. High Dimensional Cytometric Assay for Clinical Assessment of Vascular Health

    SBC: CYTOVAS, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Atherosclerotic disease is a prevalent and progressive condition that can be difficult to assess during sub- clinical stages. A developing and exciting biomarker strategy is the measurement of microparticles (MPs) and assessment of circulating progenitor and mature endothelial cells. All eukaryotic cells shed MPs in response to activation or apoptosis. Elevatio ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Smart Anatomic Recognition System to Guide Emergency Intubation and Resuscitation

    SBC: BRIO DEVICE, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Over 3 million emergency intubations are performed in the US every year and failure rates can be as high as 50% (3-5). Success is highly dependent on how frequently the responder performs this life-saving procedure on humans (6). Brio Device, LLC, an airway management medical device company, is addressing the need to decouple the success of the procedure from t ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Crosslink augmentation to resist snoring and obstructive sleep apnea syndrome

    SBC: ORTHOPEUTICS, LP            Topic: NHLBI

    DESCRIPTION (provided by applicant): Snoring is a condition that affects people of all ages, with a reported prevalence of up to 48% of men and 34% of women. Snoring poses not only an inconvenience with regard to sleep-cycle disruption of the sufferer's bed partner and family, but it can also lead to sleep-deprivation in the sufferer and to a more serious and sometimes life-threatening condi ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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