Award Data

The broader impact of this Small Business Innovation Research (SBIR) Phase II project seeks to develop an improved era of infectious disease management, allowing rapid intervention for antibiotic therapy to stem the 30% mortality rate and associated cost impact of sepsis. With some 49 million cases worldwide and a 25-30% mortality rate, sepsis claims 11 million lives annually. Sepsis cases have be ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project seeks to develop of a safe and curative, minimally invasive procedure leading to long-lasting outcomes for patients with varicocele. Varicocele is the most common cause of male infertility and is also associated with testicular pain, erectile disfunction, and low free testosterone. Varicocele ...

The broader impact/commercial potential of this Small Business Innovation Research Phase II project is to develop a mature, market-ready approach for building targeted, readily synthesizable inhibitors of viral proteases. The technology will extend the discovery platform to new targets and disease indications and build a biochemical foundation for progressing preclinical programs to promising lead ...

The broader impact of this Small Business Innovation Research (SBIR) Phase II project will be to reduce video and image copyright-related liability for social media companies and retain profits for digital media licensing companies and other content owners/distributors who are holding or enforcing content rights. Beyond content protection, the technology being developed can also address the emergi ...

"SkyNano, Endeavor Composites, and The University of Tennessee Knoxville propose to develop a composite panel that contains CO2-derived carbon nanotubes (CNTs), recycled carbon fiber waste, and bio-derived natural fibers that exhibits excellent mechanical and functional properties, while maintaining a carbon-negative footprint on a cradle-to-gate and cradle-to-grave basis. By the end of the Phase ...

"SkyNano, Endeavor Composites, and The University of Tennessee Knoxville propose to develop a composite panel that contains CO2-derived carbon nanotubes (CNTs), recycled carbon fiber waste, and bio-derived natural fibers that exhibits excellent mechanical and functional properties, while maintaining a carbon-negative footprint on a cradle-to-gate and cradle-to-grave basis. By the end of the Phase ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase II project will be the development of the first minimally invasive cryoablation solution to treat high-risk patients with gallbladder disease. The current gold standard for treating gallbladder disease is surgical removal of the gallbladder. While this procedure works well for healthy patients, the use ...

This Small Business Innovation Research (SBIR) Phase II project seeks to develop a novel noninvasive device for detecting and diagnosing gastroesophageal reflux. Reflux occurs when a bolus of gastric contents flows from the stomach into the esophagus. Symptoms of reflux can include chronic cough, choking, difficulty breathing or swallowing, upper airway infections, and chest pain. These symptoms c ...

The broader impact /commercial potential of this Small Business Technology Transfer (STTR) Phase I project is to derisk a new membrane manufacturing technology for biogas upgrading.Renewable natural gas (RNG) is attractive as a carbon neutral energy source as it is derived from organic wastes such as food waste, agricultural waste, and municipal biosolids. RNG is part of biogas and requires cost- ...

The broader impact/commercial potential of this Small Business Innovation Research (SBIR) Phase I project consists of advancing methods for preparing deoxyribonucleic acid (DNA) for sequencing. Prior to sequencing a biological sample, DNA must be liberated from cells and separated from proteins and other unwanted debris, and then mixed with specialty buffers and chemical agents. This skilled task ...