Award Data

The widespread use of Hybrid Electric Vehicles (HEVs) and Plug-in Hybrid Electric Vehicles (P-HEVs) will require batteries with improved energy density. An improved energy density will lead to longer operating times and improved system efficiency. This project will explore the development of an advanced anode to increase the battery¿s energy density. In particular, the project will involve the ...

In order to meet the objectives of the U.S. contribution toward diagnostics for the ITER fusion reactor, a significantly higher conversion efficiency must be achieved by the CO2 laser frequency doubler, in order to enable very low noise operation of the sensing interferometer. For the two-color dispersion interferometer that was developed for tokamak plasma monitoring, the nonlinear optical (NLO) ...

The United States Air force, DARPA, and other military and civilian organizations have current, active programs focused on increasing the performance and reliability of current, next generation and generation after next aircraft. An element of nearly all of these programs is boundary layer control – passive and/or active means to delay separation and transition. Boundary layer control is a rec ...

DESCRIPTION (provided by applicant): The zebrafish, Danio rerio, has become widely accepted as a model for human disease. Small molecule screens have been performed to identify both modifiers of normal cardiovascular processes and modifiers of cardiovascul ar disease. High-throughput systems under development aim to measure heart rate but do not address other critical parameters of cardiovascular ...

Physical Sciences Inc. (PSI) proposes a Phase II program to develop, test and implement in a hardware/software system an advanced set of statistics-based algorithms for detecting anomalous events for a wide range of seismic activity levels. Phase I quantitatively demonstrated the feasibility of our statistics-based approach, yielding event detection with p_d > 90%, P_fa < 1%, location accuracy < 1 ...

Physical Sciences Inc. (PSI) proposes to develop a signal processing system to facilitate real-time detection of chemical and biological threats via analysis of hyperspectral infrared imagery produced by portable imaging spectrometers. The processor will support simultaneous detection of up to 16 different target materials using a spectral-matching-based detection algorithm. For datacubes acquir ...

Physical Sciences Inc. (PSI) has demonstrated that the cyromilling process is capable of producing aluminum/copper oxide super-thermite powder. The cryomilling process, as developed, offers a significant cost advantage through the use of micron-sized aluminum as the starting material. Combustion characteristics of the cryomilled materials were shown to exhibit properties equivalent to or close to ...

DESCRIPTION (provided by applicant): Response to carbidopa/levodopa (CD/LD), the most efficacious therapy in Parkinson's disease (PD), is often variable among patients. At initiation of therapy, some patients require higher doses than others in order to achieve the same benefit. Still others never fully respond to CD/LD despite being on recommended doses. As the disorder progresses incomplete resp ...

DESCRIPTION (provided by applicant): The overall goal of this proposed research is to develop a multi-well insert apparatus that will facilitate rapid automated detection of reporter genes in living fish from embryonic to juvenile stages of development. This system will be relevant for any zebrafish-based assay which utilizes fluorescent or luminescent reporter genes as a means of evaluating a bio ...

DESCRIPTION (provided by applicant): Project Summary/Abstract A novel technique for imaging biological tissue without labeling or staining, called Mueller matrix polarization microscopy, is introduced for visualizing the distribution of the anisotropic complex refractive index, an intrinsic property of the internal cellular and tissue microstructures. In addition to linear birefringence (the only ...