Award Data

APPROXIMATELY 200,000 TOTAL KNEE REPLACEMENTS AND 200,000 TOTAL HIP REPLACEMENTS ARE PERFORMED YEARLY IN THE UNITED STATES. THE PROSTHESES MUST BE AS RELIABLE AS POSSIBLE. CERAMICS ARE WELL KNOWN AND VALUABLE CLINICAL MATERIALS, BUT FIND LIMITED USE DUE TO THEIR BRITTLENESS. IT WAS FOUND THAT ZRO2 HAS BETTER STRENGTH AND TOUGHNESS THAN A12O3, BUT CAN NOT BE USED IN KNEE PROSTHESES, SINCE KNEE C ...

Wearable sensors provide an enhanced degree of warfighter protection by enabling real-time and continuous monitoring of health metrics, biological/chemical threats, location, and biofeedback of troops. It is critical for the warfighter that wearable sensing solutions be stretchable, lightweight and reliable to provide the benefits of the sensing technology without physical hindrance. To advance th ...

DESCRIPTION (provided by applicant): A major concern regarding drugs in development is cardiac toxicity. Commonly, drugs in development can cause changes to cardiac contractility, the force with which the heart beats, and cardiac rhythmicity, resulting in toxic side effects. The purpose of this Phase 1 proposal is to develop zebrafish assays for measuring drug-induced changes in cardiac contractil ...

In this document, Securboration proposes a Phase II effort to develop a technology called Zero-Trust Analytics for Machine Learning SecDevOps (ZTA-ML or “Zeta ML”). The overarching goal of the proposed effort will be to develop a zero-trust solution that enhances the security posture of operationally deployed ML software systems. ZTA-ML will be implemented as a dynamic analysis toolchain for M ...

CARBON-CARBON AND FILAMENT WOUND COMPOSTIES NOT ONLY OFFER UNIQUE MECHANICAL PROPERTIES AND CAPABILITIES, BUT ARE DIFFICULT TO INSPECT AND DETERMINE MANUFACTURING INTEGRITY. DEFECTS OF INTEREST ARE VARIATIONS IN DENSITY AND CHEMICAL SPECIES, VOIDS, AND CRACKS. A NEW IMAGING TECHNOLOGY, ZT, HAS BEEN DEVELOPED WHICH IS INTRINSICALLY TOMOGRAPHIC, IMAGES IN PLANES PARALLEL TO THE OBJECT SURFACE, AND I ...

We have proposed the development of a novel, low frequency, directed energy concept for neutralizing IEDs at a safe distance in front of moving vehicles. The concept is based on launching an"Energetic RF Zenneck-mode Surface Waves"(Z-waves), which unlike conventional RF free field propagation, its intensity falls off at a 1/r rate, and is capable of penetrating ground and shielded enclosures. The ...

Roadside IED's are expected to be a significant tool in our enemy"s arsenal for years to come. They are the tool of choice since they are cheap, low cost and require very little skill to develop and deploy. Thus, there is a compelling unmet need for a directed energy device that can reliably and rapidly neutralize buried IEDs over large areas. The existing IED defeat systems are based on HPM ...

Marine biofouling is a significant problem on ship hulls, increasing fuel consumption and decreasing speed/efficiency. Traditional coatings prevent fouling through controlled release of biocidal compounds (e.g. metals, copper or zinc, or organics, tributyltin). The continuous leaching of these biocides has raised environmental impact concerns. A variety of non-biocidal technologies have been attem ...

DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project is designed to develop new zwitterionic click methodology for orthopedic surfaces with enhanced durability. As Americans live longer and more actives lives, totaljoint replacement is becoming more common. Current orthopedic joints have average life spans of approximately 20 years. By that point wear on th ...

DESCRIPTION (provided by applicant): Project Summary This Phase I SBIR project is designed to develop new zwitterionic graft methodology for orthopedic surfaces with enhanced durability. As Americans live longer and more active lives, total joint replacement is becoming more common. Current orthopedic joints have average lifespans of approximately 20 years. By that point wear on the joint causes p ...