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APPLICANT'S DESCRIPTION: DNA fingerprinting, or profiling, is widely used for paternity cases and criminal investigations (forensics). Current methodologies are cumbersome, expensive and often fail to produce interpretable results. A minor groove binder (MGB) has been developed that greatly enhances the ability of oligonucleotide probes to discriminate single nucleotide polymorphisms (SNPs) in the ...

Not Available This program seeks to capitalize on newly available quantum cascade semiconductor lasers, which operate in the mid-infrared spectral region at room temperature, to demonstrate the next generation laser absorption trace gas sensor. A quantum cascade laser-

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DESCRIPTION (provided by applicant): We propose to conduct research and development towards a ceramic scintillator composed of LSO:Ce. It is well known that crystalline LSO is one of the highest performance scintillators in terms of light output and timing. Only one impediment stands in the way of LSO assuming a commanding position in most areas of medical applications: its unacceptably high co ...

65264 Many existing and virtually all new construction installations of commercial and residential HVAC duct systems are outside of the conditional building space, and are often outside the building envelope altogether (e.g. rooftop), wasting an enormous amount of energy. Improving insulation values from conventional R-4 per inch to R-10 to R-12 per inch performance can eliminate more than 50 ...

70549 The performance and environmental impact of coal-fueled gasifiers is strongly dependent upon the properties of the feedstock coal. Real-time knowledge of feedstock parameters, such as heating value and ash and sulfur content, would enable boiler operators to maximize plant efficiency. Also, real-time data on trace metals, such as mercury, cadmium, arsenic, and lead, not only would prov ...

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Innovation in key technology areas will provide the dramatic advances needed for small- to mid-sized space-based flywheel energy storage systems. Our vision for this work is based on our understanding of high-speed machinery and our background in similarly sized flywheel systems. Based on this experience, we have focused this SBIR program on two areas: the main bearing system and the motor-generat ...