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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

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  1. Frequency Doubler for CO2 Laser ITER Diagnostics

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    In order to meet the objectives of the U.S. contribution toward diagnostics on the ITER fusion reactor, which is being built by an international team, the CO2 laser frequency doubler must achieve a significantly higher conversion efficiency, in order to enable very low noise operation of the sensing interferometer. This project will develop nonlinear optical (NLO) orientation-patterned gallium ar ...

    SBIR Phase II 2009 Department of Energy

  2. High-resolution Smart Optical Probe for Breast Biopsy Guidance

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Fine needle aspiration biopsy (FNAB) is a rapid and cost-effective procedure that uses a syringe to sample fluid from a cyst or remove clusters of cells from a solid mass for diagnostic purposes. The effectiveness of FNAB is operator-dependent and the diagnostic yield could be low, especially for adipose- rich tissue and masses where the percentage of non-diagn ...

    STTR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health

  3. Image guided intervention system for pancreatic cystic lesions

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This proposal addresses a need for an improved technology for both diagnosis and treatment of patients with cystic neoplasms of the pancreas. Currently, endoscopic ultrasound-guided fine needle aspiration (EUS-FNA) technology is used as a first line of diagnosis for pancreatic lesions. However, the complex regional anatomy of the pancreas and the very difficult ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health

  4. AIRBORNE HEAVY METAL MONITOR

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    N/A

    SBIR Phase II 1999 Department of Health and Human Services

  5. DNA APTAMER ARRAYS FOR DETECTION OF CANCER BIOMARKERS

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    The major goal of cancer proteomics is detection and identification of human tumors based on 'protein signatures' characteristic for different malignancies, Early tumor detection is critical for effective treatment and patient survival. Simultaneous identification of multiple cancer specific protein biomarkers in body fluids would dramatically increase specificity and accuracy of cancer detection ...

    SBIR Phase I 2008 Department of Health and Human ServicesNational Institutes of Health

  6. AIRBORNE HEAVY METAL MONITOR

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    N/A

    SBIR Phase I 1997 Department of Health and Human Services

  7. Advanced Laser Source for High-speed Adaptive Optics OCT

    SBC: PHYSICAL SCIENCES INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Physical Sciences Inc. (PSI) proposes to develop a new adaptive optics imaging approach to high- speed 3D-retinal mapping with enhanced Fourier Domain Mode-locked (FDML) swept-source technology. PSI is currently engaged in ongoing development of high performance, high resolution multimodal adaptive optics (AO) retinal imagers. Such systems resolve and quant ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health

  8. Compact Hydrogen Peroxide Sensor for Sterilization Cycle Monitoring

    SBC: PHYSICAL SCIENCES INC.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Improper or incomplete sterilization of manufacturing facilities is a major cause of pharmaceutical product recalls. The economic and societal impact of these recalls is significant and difficult to quantify. Many pharmaceutical companies use vapor phase hydrogen peroxide (VPHP) to decontaminate and sterilize production facilities, including barrier isolators. ...

    SBIR Phase I 2011 Department of Health and Human ServicesNational Institutes of Health

  9. Compact Hydrogen Peroxide Sensor for Sterilization Cycle Monitoring

    SBC: PHYSICAL SCIENCES INC.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Improper or incomplete sterilization of manufacturing facilities is a major cause of pharmaceutical product recalls. The economic and societal impact of these recalls is significant and difficult to quantify. Many pharmaceutical companies use vapor phase hydrogen peroxide (VPHP) to decontaminate and sterilize production facilities, including barrier isolators. ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health

  10. Fully Automated Angiogenesis Drug Discovery Assay in Zebrafish

    SBC: PHYSICAL SCIENCES INC.            Topic: NHLBI

    DESCRIPTION (provided by applicant): The zebrafish, Danio rerio, has become widely accepted as a model for human disease. Small molecule screens have been performed to identify modifiers of vascular patterning but this process has been performed at relatively low throughput since the tools for fully automated processing are not yet available. We propose to develop a novel, high-throughput screenin ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
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