Award Data

ABSTRACT: In this effort, Freedom Photonics will develop a high-sensitivity high-resolution coherent imaging system based on a Si avalanche photodiode (APD) array and corresponding bias and read-out electronics. This will be a monolithic APD and ROIC (readout-integrated-circuit) focal plane array (FPA) system. We start from a proven high-performance CMOS electronics backplane and build the photon ...

This Small Business Innovation Research Phase I Project aims at developing an advanced biotechnology for bioremediation of animal wastewater by using oil-rich microalgae. Rapid growing animal farming industries (hog, poultry, cattle, and dairy) have generated tremendous amount of animal wastes that have become important sources for environmental pollution. Current method of disposing untreated ani ...

NON-TECHNICAL SUMMARY: Nostoc commune is an edible cyanobacterium forming the spherical macrocolony, which is used as a potent herbal medicine and dietary supplement. Due to its nutraceutical and pharmacological value, the N. commune has received increasing attention, and the market demand has grown drastically during the last decade. However, low yield and unstable quality caused by inadequate pr ...

This Small Business Innovation Research (SBIR) Phase I project proposes to improve the bioavailability of astaxanthin from the green algae, Haematococcus pluvialis, through molecular genetic manipulation of the organism. Natural astaxanthin is a potent bioactive antioxidant and offers tremendous potential for use in nutraceutical, pharmaceutical, aquaculture, and poultry industries. The green alga ...

This Small Business Innovative Research (SBIR) Phase I project demonstrates the feasibility of producing stearidonic acid from microalgae for human consumption to combat cardiovascular diseases (CVD). The cardiovascular benefits of fish oil enriched in omega-3 polyunsaturated fatty acids (n-3 PUFAs) are well-documented. Despite overwhelming evidence and strong recommendations supporting the health ...

This Small Business Innovative Research (SBIR) Phase I project aims to develop an innovative large-scale photobioreactor for production of natural astaxanthin from Haematococcus strains. The phase I research plan is to construct and evaluate an innovative modular flat-plate photobioreactor for mass culture of the organism. The improved production system, along with a genetically improved Haematoco ...

This Small Business Innovative Research (SBIR) Phase II reserach develops an innovative biotechnology for commercial production of natural astaxanthin using genetically improved microalgal strain(s) grown in a proprietary large-scale photobioreactor, and to demonstrate the effectiveness of the new strains in improving bioavailability of astaxanthin. The proposed R&D efforts aim to overcome the maj ...

The crude oil will be depleted within 40 years, alternative fuels have to be developed to drive our transportation systems, and biodiesel appears to be the most promising fuel of the future. Biodiesel is renewable, non-toxic, and biodegradable, it can be used in existing diesel engines without modifying the engin, and can be blended in at any ratio with petroleum diesel. However, the development o ...

Proteios Technology has developed a proprietary platform that does not rely on antibodies nor magnetic beads to isolate cell subpopulations. The platform has been validated on T cells using the CD4+ and CD8+ subpopulations for the production of autologous CAR-T cell therapies. They are currently extending the platform for the isolation of Natural Killer (NK) cells for the production of autologous ...

The Navy Desktop Computer (DTC) hosting the Submarine Fleet Mission Program Library (SFMPL) is a dynamic computer system capable of providing support accross a spectrum of activities from basic administrative duties to complex tactical decision making support. Readily available access to training for personnel using this system is critical to ensuring that its capabilities are used. This training ...