Award Data

DESCRIPTION (provided by applicant): The zebrafish, Danio rerio, has become widely accepted as a model for human disease. Small molecule screens have been performed to identify modifiers of vascular patterning but this process has been performed at relatively low throughput since the tools for fully automated processing are not yet available. We propose to develop a novel, high-throughput screenin ...

In this proposal, Physical Sciences Inc. (PSI) outlines the development of a system for remediating ammonia (NH3) produced in large confined animal feeding operations (CAFOs). The animal agricultural industry is coming under increased scrutiny due to the large volume of pollutants, in particular ammonia, produced in its operations. PSI's proposed remediation system for NH3 utilizes an adsorbe ...

Physical Sciences Inc. (PSI), in collaboration with the Center for Regenerative Medicine at the Massachusetts General Hospital (MGH), proposes to investigate a multimodal optical imaging and spectroscopy approach for in vitro characterization of engineered tissue constructs. Optical coherence tomography (OCT) imaging will be used for gross assessment of tissue morphology and birefringence properti ...

The use of a Prosthetic Replacement of the Ocular Surface Environment (PROSE) device is a revolutionary treatment for military patients that have lost their eyelids due to 3rd degree facial burns or for civilians who suffer from a host of corneal diseases. However, custom manual fitting is often a protracted painful, inexact process that require multiple fitting sessions. Training for new practio ...

Physical Sciences Inc. (PSI) proposes to develop a nanostructured, alkali vapor resistant, antireflective coating for use on Diode Pumped Alkali Laser (DPAL) windows. The materials will be deposited from chemical solutions via dip coating. A dual layer AR coating design is proposed including a dense alkali impervious base layer and a porous non-reactive top layer. The result of the Phase I effort ...

Long range interceptor missiles rely on divert and attitude control systems (DACS) powered by liquid hypergolic propellants, a fuel and an oxidizer. Specifically, the present generation of SM-3 missiles employs monomethylhydrazine (MMH) and nitrogen tetroxide (NTO). Sensors, able to detect

ABSTRACT: Physical Sciences Inc. (PSI) and Alliant Techsystems (ATK) propose to develop novel structural reactive materials with mechanical and energetic characteristics particularly applicable to low collateral damage munitions, weaponized UAVs, and advanced submunitions. The materials are lightweight, possess high energy density, and exhibit mechanical properties similar to aluminum. The compos ...

ABSTRACT: In this Phase I SBIR proposal Physical Sciences Inc. (PSI) outlines the development of a scaleable, multi-use laser sensor with size, weight and power (SWaP) characteristics that are compatible with small, remotely piloted aircraft (RPA). PSI"s approach will result in a modular sensor that can be scaled to the requirements of a specific RPA and mission. Current range finder and designat ...

ABSTRACT: ORS requires rapid delivery of low-cost payloads that meet the needs of unplanned and unanticipated spacecraft missions. Physical Sciences Inc. (PSI) will provide ORS, the Air Force, and other customers with a low-cost, rapidly-fabricated deployable antenna for use in a wide range of potential missions. The PSI team will use a combination of commercially available manufacturing techniqu ...

ABSTRACT: Physical Sciences Inc. (PSI) proposes to develop a passive optical taggant that utilizes the absorptive and emissive properties of colloidal quantum dots (QDs). The device will be a flexible, robust, and low-cost QD composite that is deployable on vehicles and soldiers. The taggant device will emit from 3.9-4.1 um with quantum yields>30% when excited by standard military laser designato ...