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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY23 is not expected to be complete until September, 2024.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201491 - 201500 of 204843 results
  1. Computer-based HIV Prevention for Seropositive Men

    SBC: Amplyx Pharmaceuticals, Inc.            Topic: NINDS

    DESCRIPTION (provided by applicant): Cryptococcosis is a devastating opportunistic infection caused primarily by Cryptococcus neoformans. Cryptococcosis most often spreads to the brain, causing cryptococcal meningitis (CM), and is fatal if left untreated.CM is the AIDS-defining central nervous system (CNS) illness and occurs in 60-70% of HIV positive individuals worldwide. In sub-Saharan Africa, C ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Robust High-throughput Mechanical Phenotyping Platform for Clinical Diagnostics

    SBC: MICROTRANSPONDER, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): The Specific Aim of this proposal is to test the feasibility of using a novel method of enhancing neuroplasticity for the purpose of producing clinically significant improvements in the ability of stroke patients to perform their activities o daily living (ADLs). One of the major goals of MicroTransponder is to translate pre-clinical findings of enhancing neur ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. Risperidone Subcutaneous Implant

    SBC: VULINTUS, INC            Topic: NINDS

    DESCRIPTION (provided by applicant): More than 100,000 patients worldwide have some form of permanently implanted neural interface in the brain. Although effective, these interfaces have several technical limitations that limit the full scope of their clinical efficacy. For severa decades, silicon technology has been touted as the most likely candidate for creating more advanced neural interfaces. ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. A Dynamic DNA Discovery Kit: Hand-on Exploration of DNA Structure and Function

    SBC: 3D Molecular Designs, LLC            Topic: OD

    DESCRIPTION (provided by applicant): The goal of this project is to design and prototype a dynamic physical model of DNA that students will use in an active learning environment to explore the 3-D structure of double- stranded DNA - and then easily untwistinto a flat, 2-D ladder model in which the two strands of DNA will be separated to serve as templates in the processes of DNA replication and RN ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. Media-based culturally-relevant parent education for divorced Latino families

    SBC: HELIXBIND INC            Topic: OD

    DESCRIPTION (provided by applicant): This Small Business Innovation Research Phase I project will establish feasibility of a novel method for detecting and diagnosing polymicrobial infections in biomedical laboratory animals. Polymicrobial infections in laboratory animals are of significant concern to the research community as they have a demonstrated detrimental effect on experimental outcome. It ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Modulation of the Innate Immune System by Fisetin for the Treatment of AD

    SBC: COLLABORATIVE DRUG DISCOVERY, INC.            Topic: NCATS

    DESCRIPTION (provided by applicant): Collaborative Drug Discovery, Inc. (CDD) proposes to create an innovative software module that will help biologists to quickly and easily encode their plain-text biological assay protocols into formats suitable for computational processing. The software will enable scientists engaged in early stage drug discovery to automatically identify, sort and compare data ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Piezoelectric MEMS microphones for hearing aids

    SBC: CytoVale, Inc            Topic: NCATS

    DESCRIPTION (provided by applicant): There has been increased interest in using mechanical properties of cells as label-free biomarkers for applications in basic biology and clinical diagnostics. Increased single-cell deformability has been correlated withmalignancy in cell lines and patient samples for example. In contrast to conventional molecular biomarkers a mechanical property is intrinsic to ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Developing an Improved Electrocompetent E. coli Host

    SBC: Pro-Change Behavior Systems, Inc.            Topic: NCATS

    DESCRIPTION (provided by applicant): Chronic musculoskeletal pain creates a significant public health burden. Veterans are disproportionately affected by chronic musculoskeletal pain, and in particular, chronic low back pain (CLBP). The frequency and extent of co-occurrence of pain and PTSD, pain and Traumatic Brain Injury (TBI), and all three conditions (Post-deployment Multi-symptom Disorder (PM ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. Adapting wireless glucometer to boost opioid dependence medication compliance

    SBC: Ginkgo BioWorks            Topic: NCATS

    DESCRIPTION: Plant-derived secondary metabolites have proven to be a rich source of pharmaceuticals. From 1981 to 2010, over 65% of the 1355 new chemical entities introduced worldwide were natural products or natural product derivatives. The benzylisoquinoline alkaloids (BIAs) represent a diverse class of secondary metabolites (2500 known structures) with a broad range of pharmacological activiti ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Selectin targeted ultrasound contrast agents for detection of acute coronary synd

    SBC: ORPHAGEN PHARMACEUTICALS, INC.            Topic: NCATS

    DESCRIPTION (provided by applicant): Retinitis pigmentosa (RP), a hereditary disease of the retina affecting 100,000 Americans, is the major cause of blindness in adults aged 25-60. There is no approved therapy for the disease and gene therapy, while promising, is limited because of the diversity of underlying genetic mutations. The abnormal localization of rod opsin, the highly-expressed major pr ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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