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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201491 - 201500 of 207728 results
  1. IMPLANTABLE BATTERYLESS PACEMAKER AND TELEMETRY DEVICE FOR SMALL ANIMALS

    SBC: INDUS INSTRUMENTS            Topic: NHLBI

    Cardiac arrhythmias are a major public health burden. There are 250,000 - 400,000 sudden cardiac deaths (SCD) in the US every year, accounting for up to 20% of all deaths in adults; the majority of these are due to ventricular fibrillation. In addition, approximately 2.5 million Americans now suffer atrial fibrillation (AF), a number that is expected to surpass 5 million by 2050. Strong evidence i ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  2. OTHER FUNCTIONS- SBIR PHASE II: TOPIC 53, INNOVATIVE TOOLS, TECHNIQUES AND SOFTWARE FOR THE SCREENING, RECRUITMENT AND FOLLOW-UP OF PARTICIPANTS IN PEDIATRIC RESEARCH

    SBC: ARCHIE MD INC.            Topic: NHLBI

    Screening and recruitment of children into multi-center clinical trials poses unique challenges not seen in the adult population. Screening tools, recruitment strategies, registries to provide baseline data on which to base future clinical trials and waysto document follow-up are needed. Validated materials and tools applicable to diverse populations and for use in community practices, which often ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  3. OTHER FUNCTIONS- SBIR PHASE II, TOPIC 53, INNOVATIVE TOOLS, TECHNIQUES AND SOFTWARE FOR THE SCREENING, RECRUITMENT AND FOLLOW-UP OF PARTICIPANTS IN PEDIATRIC RESEARCH

    SBC: New England Research Institutes, Inc.            Topic: NHLBI

    Screening and recruitment of children into multi-center clinical trials poses unique challenges not seen in the adult population. Screening tools, recruitment strategies, registries to provide baseline data on which to base future clinical trials and waysto document follow-up are needed. Validated materials and tools applicable to diverse populations and for use in community practices, which often ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  4. OTHER FUNCTIONS- RECOMBINANT ANTIBODIES AS AFFINITY CAPTURES

    SBC: AVANTGEN INC            Topic: NHLBI

    One of the biggest roadblocks to the translation of basic proteomic discoveries to potential clinical applications is the lack of robust and sensitive reagents that can capture a given protein reproducibly from different types of matrixes. While antibodieshave been the major players of protein capture, alternate reagents are urgently needed to overcome the lack of sensitivity, specificity, and rep ...

    SBIR Phase II 2012 Department of Health and Human ServicesNational Institutes of Health
  5. NOVEL PHARMACOTHERAPIES FOR ALCOHOLISM, TOPIC #4409/24/2012- 03/23/2013

    SBC: NAPROGENIX, INC.            Topic: NIAAA

    Alcoholism is a complex condition in which there are many potential molecular and therapeutic targets for pharmacotherapy. This fast track SBIR contract aims to investigate compounds targeted on the glutamate/NMDA receptor (NMDAR) and the nicotinic receptor for acetylcholine (nicAChR). These targets have direct relevance to several of the major therapeutic targets including detoxification of a ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  6. IGF::OT::IGF OTHER FUNCTIONS NOVEL ALGORITHMS FOR IN VIVO ENDOSCOPIC 3D SURFACE IMAGE RECONSTRUCTION, MEASUREMENT, and REGISTERATION

    SBC: XIGEN, LLC            Topic: NCI

    Primary objective of this Phase 1 SBIR is to develop advanced algorithms and software that enable in vivo processing of endoscopic stereo images for 3D surface reconstruction, measurement, visualization and registration (3D-RMVM). Based on the reconstructed 3D surface profile, quantitative measurement can be made and 3D registration between the reconstructed endoscopic 3D surface image and the pre ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  7. IGF::OT::IGF OTHER FUNCTIONS SCALABLE AUTOMATED BRAIN TUMOR SEGMENTATION

    SBC: INFOTECH SOFT, INC.            Topic: NCI

    Brain tumor segmentation in Magnetic Resonance Imaging is an important task for neurosurgeons, oncologists, and radiologists to assess disease burden and measure tumor response to treatment. In 2008, over 237,000 individuals worldwide are estimated to havebeen diagnosed with malignant brain and central nervous system tumors with over 174,000 deaths. Detection of brain tumors with the exact locatio ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  8. IGF::OT::IGF OTHER FUNCTIONS AUTOMATED DATA SEGMENTATION TO ENABLE REAL-TIME IN VIVO 3-D IMAGE RECONSTRUCTION

    SBC: DIAGNOSTIC PHOTONICS, INC.            Topic: NCI

    In vivo medical imaging is becoming an indispensable tool in the screening, diagnosis, staging, treatment, and monitoring of cancer and a host of other diseases. However, the full potential of these technologies has been severely limited by image processing time and memory management of large data sets. In order to address this problem, Diagnostic Photonics, Inc. proposes to develop and distribute ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. IGF::OT::IGF OTHER FUNCTIONS TOPIC 301, PHARMACO-KINESIS CORPORATION PHASE I ENTITLED A VEGF NANOSENSOR TO MONITOR TUMOR PROGRESSION

    SBC: PHARMACO-KINESIS CORPORATION            Topic: NCI

    The overarching goal of this project is to develop and commercialize a nanotechnology-based diagnostic platform capable of monitoring tumor microenvironments in vivo. Specifically, PKC will develop a biosensor based on carbon nanotube transistor technologies for monitoring levels of vascular endothelial growth factor (VEGF) proteins, a general biomarker associated with tumors. In the Phase I s ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  10. IGF::OT::IGF OTHER FUNCTIONS TOPIC 301, PHYSICAL OPTICS CORPORATION PHASE I ENTITLED NANOPARTICLE ENHANCED MAGNETO-ACOUTIS TOMOGRAPHY

    SBC: Physical Optics Corporation            Topic: NCI

    The overall goal of this project is to address the NCI need by developing and, for the first time, demonstrating relaxation-time-selective magneto-acoustic detection of functionalized iron oxide nanoparticles. Functionalized magnetic nanoparticles will be developed for specific aggregation at the tumor site. A nanoparticle-enhanced magneto-acoustic tomography (NEMAT) detection system will be de ...

    SBIR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
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