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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201501 - 201510 of 207728 results
  1. Use of Novel Cox-2 Inhibitors in Neurological Disorders

    SBC: ONCONOVA THERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Strategies aimed at limiting and repairing the damage attributed to oxidative stress may slow the advance of numerous age-related diseases. Numerous studies indicate that the enzyme cyclooxygenase-2 (COX-2) is induced by oxidative stress, contributes to oxidative stress, and promotes subsequent neuronal injury. In this application we propose continuation of our ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Use of novel fluorescent tracers to develop a comprehensive retinal biomarker database that maps the heterogeneity of Alzheimer's pathogenesis

    SBC: Amydis Diagnostics Inc.            Topic: NIA

    Project Summary Alzheimer’s disease (AD), the most common form of dementia, has traditionally been defined by the accumulation of amyloid beta (Aβ) in neuritic plaques and hyperphosphorylated tau in neurofibrillary tangles. However, recent evidence indicates that AD is better viewed as a continuum of disease with a broader degree of mechanistic and pathological heterogeneity. For example, ~15% ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Use of Novel, Low-Cost Additives to Improve Sorbent Efficiency for Control of Mercury Emissions in Coal-Fired Power Plant Flue Gases

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    109 Use of Novel, Low-Cost Additives to Improve Sorbent Efficiency for Control of Mercury Emissions in Coal-Fired Power Plant Flue Gases--Physical Sciences Inc., 20 New England Business Center, Andover, MA 01810-1022; Mr. Joseph R. Morency, Principal Investigator Mr. George E. Caledonia, Business Official DOE Grant No. DE-FG02-97ER82456 Amount: $74,996 Although coal-fired power plants are n ...

    SBIR Phase I 1997 Department of Energy
  4. Use Of Novel Momentum Transfer Technology And CFC Replacement Solvents For All-dry Photoresist And Wafer Cleaning

    SBC: Emadel Enterprises Inc.            Topic: N/A

    A 6-month, Phase I Small Business Innovation Research (SBIR) program is proposed to conduct proof-of-principle work on a novel process which uses momentum transfer mechanisms and liquid carbon dioxide for all-dry wafer cleaning. Under an earlier, Phase I project, the basic principle of momentum transfer has been demonstrated as effective, using high purity liquid carbon dioxide sprays accelerated ...

    SBIR Phase I 1993 Department of DefenseDefense Advanced Research Projects Agency
  5. Use of novel vector to defeat fungal pathogens using siRNAs

    SBC: SILVEC BIOLOGICS INC            Topic: 82

    Trees vines and bushes are plagued by pathogens causing over $100B in annual damage.Fungi are of particular concern causing 85% of pathogen-related crop losses. For many fungi likeBotrytis cinerea there are no varieties with natural resistance in its host range. As B. cinerea isestimated to cause over $10B in annual crop losses there is a strong driver for effective controlsolutions especially one ...

    SBIR Phase II 2023 Department of Agriculture
  6. Use of nutrient rich insect base to create pasta and rice mimicking food products

    SBC: BUGEATER LABS INC            Topic: 85

    The global population is expected to reach 9.7 billion people by 2050 with food demand to increase by 70% during that time (van Huis, A. et. al, 2015 and Shockley, 2014). Nearly 200 million children worldwide suffer from malnutrition with the World Health Organization estimating that 54% of child mortality is the result of malnutrition (Shockley, 2014). With land and water use already stressed wit ...

    SBIR Phase I 2016 Department of Agriculture
  7. Use of Ocean Plastic Waste in Road Construction

    SBC: ALTISORA LLC            Topic: 15a

    Roughly 8 million metric tons of plastic waste pollute the world’s oceans annually and detrimentally impact the environment. It is estimated that ocean plastic waste costs society up to $2.5 trillion/year. Abandoned fishing nets, one type of ocean plastic waste, are a major threat to marine habitats and biodiversity.These “ghost nets” account for 52% of the Great Pacific Garbage Patch where ...

    SBIR Phase I 2020 Department of Energy
  8. Use of Pattern Recognition to Optimize Site Investigation

    SBC: INNOVATIVE TECHNICAL SOLUTIONS, INC.            Topic: N/A

    NOVASOL is pleased to propose development of pattern recognition technology in the analysis of data related to remedial investigations at Dense Non-Aqueous Phase Liquid (DNAPL) contaminated sites. We have named our concept Pattern Recognition OptimizationTechnology for Investigation of Contaminated Sites (PROTICS). The proposed PROTICS system will consist of geostatistical modeling, spatial visu ...

    SBIR Phase I 2003 Department of DefenseAir Force
  9. USE OF PCR FOR DIAGNOSING HIV-1 INFECTION IN PEDIATRIC PATIENTS

    SBC: Biotech Research Laboratory            Topic: N/A

    PREVALENCE STUDIES FOR HIV-1 INFECTION IN NEWBORNS ARE DIFFICULT TO OBTAIN BECAUSE THE COMMONLY USED ANTIBODY ASSAYS ARE NOT APPROPRIATE FOR TESTING BABIES. BABIES CARRYTHE MATERNAL ANTIBODY FOR UP TO 12 TO 18 MONTHS AFTER BIRTH,SO ALL BABIES BORN TO SEROPOSITIVE MOTHERS WILL ALSO TEST POSITIVE. YET 40 TO 50 PERCENT OF THESE BABIES ARE NOT ACTUALLY INFECTED. IN THIS RESEARCH, POLYMERASE CHAIN REAC ...

    SBIR Phase II 1992 Department of Health and Human Services
  10. USE OF PCR FOR DIAGNOSING HIV-1 INFECTION IN PEDIATRIC PATIENTS

    SBC: Biotech Research Laboratory            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
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