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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201531 - 201540 of 207712 results
  1. Cell-based screening of combinatorial siRNA libraries

    SBC: CYNTELLECT, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): RNA interference (RNAi) is a specific post-transcriptional gene silencing pathway mediated by intracellular dsRNAs of 21-23 bp in length known as small interfering RNA (siRNA). Since the recent discovery of effective siRNA-mediated gene silencing in mammalian cells, there has been significant validation and enormous interest in the approach from both academic a ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Safety of intraarticular N-acetylglucosamine

    SBC: ARTYX PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Osteoarthritis (OA) is the most prevalent joint disease, causing joint pain and dysfunction. OA is also associated with substantial co-morbidity and reduces life expectancy. Pharmacologic therapy is limited to symptom modification and disease-modifying therapies are currently not available. Furthermore, even symptom-modifying therapies are limited in efficacy a ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Smart Optical Probe for Guidance of Fine Needle Biopsy

    SBC: PHYSICAL SCIENCES INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Fine needle aspiration biopsy (FNAB) is a cost-effective and rapid procedure that uses a syringe to sample fluid from a cyst or remove clusters of cells from a solid mass for diagnostic purposes. The effectiveness of FNAB is operator-dependent and the diagnostic yield can be low, especially for adipose-rich and masses where the percentage of non-diagnostics asp ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. PTH (7-34) for Chemotherapy alopecia in Breast Cancer

    SBC: IGI, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I application is an extension of our ongoing program to evaluate the safety and therapeutic potential of parathyroid hormone (7-34) for stimulating and maintaining hair growth. The first part of the project includes the recruitment of 12 normal subjects. Six subjects will apply topical application of PTH (7-34) that is formulated in Novasome A cream ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Novel Organophosphorous Hydrolases for Decontamination

    SBC: LYBRADYN, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Organophosphorous (OP) neurotoxins such as paraoxon, sarin, soman, VX, and Russian-VX, are a broad class of chemicals commonly used as pesticides and chemical warfare (CW) agents. Currently, over 100,000 tons of chemical warfare agents are stockpiled worldwide, and thousands-of-tons of OP pesticides are released into the environment annually. Enzymes known as p ...

    SBIR Phase II 2006 Department of Health and Human ServicesNational Institutes of Health
  6. New attenuated anthrax vaccine

    SBC: DMX, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Anthrax is a rare, but deadly disease and poses a serious threat as a bioterror agent. The current anthrax vaccine uses needle injection and requires repeated immunizations for inducing protection and frequent boosts for maintaining immunity, thus making it impractical for mass immunization against this rare disease. To protect against bioterror threats, an ide ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. LabOS Closed-loop, Protocol-driven, Data Acquisition & Experiment Control

    SBC: Eidactics            Topic: N/A

    DESCRIPTION (provided by applicant): Significant Aims: Biomedical research, human performance and other laboratories that work with living subjects and perform complex experiments unanticipated by software "solution" providers, must expend significant resources creating & maintaining data acquisition and control (DAQ&C) systems that are seldom useful in other labs because of their complexity or po ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Biomarker of Cognitive Impairment in Chronic Alcoholism

    SBC: PHFR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I, STTR application focuses on developing a novel brain molecular metabolomic biomarker for cognitive impairment in chronic alcoholism. Approximately one-half to two-thirds of recently detoxified chronic alcoholics have cognitive impairment. The molecular underpinnings for the cognitive impairment and why some chronic alcoholics became cognitively im ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. Development of Force Based Orthodontic Appliances

    SBC: OSCAR, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The proposed project will develop a series of new orthodontic appliances using a patented technology. Using the appliances, clinicians will be able to quantify and manipulate the orthodontic force systems, which are not feasible at present. The ability to control the force system is essential for the advancement of orthodontical treatment. It enables the orthod ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Wireless Digital Link Between Hearing Aids

    SBC: ADVANCED MEDICAL ELECTRONICS CORP            Topic: N/A

    DESCRIPTION (provided by applicant): This proposed project seeks to prove the feasibility of an ultra-low power, digital wireless transceiver integrate circuit (1C) which would enable communication between two hearing aids. Wireless synchronization between the digital signal processors of two hearing instruments is a new technology for next generation hearing instruments. Approximately 70% of fitt ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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