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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201791 - 201800 of 207712 results
  1. High Intensity Ultrasonic Device for Mitigating Neonatal Perioperative Bleeding

    SBC: BIODESIGN RESEARCH AND DEVELOPMENT, LLC            Topic: NHLBI

    DESCRIPTION (provided by applicant): Congenital heart disease (CHD) ranges from benign lesions to life-threatening structural abnormalities. While benign lesions may resolve without intervention, severe structural lesions require complex pediatric cardiacsurgery. The reconstruction of the aortic arch in children is a complex repair in which perioperative bleeding i a significant, important and fre ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Sympathetic Nerve Activity Recorded From the Skin and Cardiac Arrhythmias

    SBC: ARRHYTHMOTECH            Topic: NHLBI

    DESCRIPTION (provided by applicant): The broad and long-term objective of this research project is to use, develop and market an instrument for the simultaneous recording of sympathetic nerve activity (SNA) and electrocardiogram (ECG) using electrodes on the skin. This method (neuECG) was discovered in Dr. Chen's research laboratory at the Krannert Institute of Cardiology, and a patent applic ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. A novel therapeutic approach for Acute Lung Injury/ARDS

    SBC: BIOMARCK PHARMACEUTICALS, LTD            Topic: NHLBI

    DESCRIPTION (provided by applicant): The objective of the proposed project is to advance the development of novel peptides targeting MARCKS (Myristoylated Alanine-Rich C Kinase Substrate) protein as platform drug molecules for the treatment of Acute Lung Injury (ALI) and its more severe form, Acute Respiratory Distress Syndrome (ARDS), thereby providing the first pharmacologic therapeutic for this ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Novel pharmacogenomic approach for identifying T cell epitopes in replacement FVI

    SBC: Haplomics            Topic: NIMHD

    DESCRIPTION (provided by applicant): About 30% of congenital Hemophilia A (HA) patients develop alloantibodies that neutralize the activity of replacement Factor (F) VIII proteins. Among African American HA patients, the frequency of inhibitor formation ismuch higher; about 50%. Inhibitor patients are typically treated with bypassing agents. Bypassing agents are more expensive and less effective t ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Evaluation of VBP15 a dissociative steroidal analogue on pain and inflammation

    SBC: REVERAGEN BIOPHARMA, INC.            Topic: NIMHD

    DESCRIPTION (provided by applicant): The treatment of pain in Sickle Cell Disease (SCD) is challenging for both patients and providers and is associated with significant disparities in healt care delivery. While the role of ongoing inflammation during vasooclusive crisis and pain is recognized, effective therapeutic interventions are lacking. Glucocorticoids, with their anti-inflammatory propertie ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Improving Asthma Control through mHealth-Based Home Monitoring

    SBC: MAD POW MEDIA SOLUTIONS, LLC            Topic: NIMHD

    DESCRIPTION (provided by applicant): Disadvantaged, urban, and minority children incur a disproportionate share of asthma prevalence and morbidity. Interventions have been shown to improve underrepresented minority (URM) youths' adherence to NIH asthma care guidelines (e.g., proper use of long-term control medication) thereby reducing asthma morbidity. One particularly promising method of int ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Location Initiated Individualized Texts for African American Adolescent Health

    SBC: MEI Research, Ltd            Topic: NIMHD

    DESCRIPTION (provided by applicant): Obesity in the U.S. has disproportionately affected African American (AA) adolescents who have almost twice the prevalence of obesity than their Caucasian peers. This is due in part to greater exposure to, and higher consumption of, 'fast' and calorie dense foods among minority vs. majority populations. Finding effective ways to address dietary habits ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Wireless sensor patch for reducing barriers to in-home sleep apnea screening

    SBC: ZANSORS LLC            Topic: NIMHD

    DESCRIPTION (provided by applicant): Obstructive sleep apnea (OSA) is the most common type of sleep apnea. OSA affects an estimated 18-40 million adults and 0.7-3% of all children in the US. OSA results in tiredness, depression and fatigue, and has severalassociated common comorbidities. It is believed that over 80% of OSA remains undiagnosed. Poorer and disadvantaged communities are at higher ris ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Multi-functional particles for stem cell isolation and expansion

    SBC: PROGENITEC INC            Topic: NIMH

    DESCRIPTION (provided by applicant): The objective of this STTR Phase I proposal is to develop novel multi-layer microparticles and demonstrate their feasibility to isolate and expand stem cells for medical research and therapeutic applications. In recentyears, stem cells have been used in a wide variety of applications, including cell- based therapies, drug screening, and models to understand the ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. A Wireless Device to Monitor and Track Fluid Consumption in At-Risk Older Adults

    SBC: Smart Activity of Daily Living, LLC            Topic: NINR

    DESCRIPTION (provided by applicant): The long term goal of the proposed project by Smart Activities of Daily Living, LLC (Smart ADLs) is to develop a device (the Smart Cup) that will improve the health of older adults by managing nutrition using smart health technology. Malnutrition (under nutrition) is a common geriatric syndrome found in older adults across the care continuum. Older adults accou ...

    STTR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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