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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201851 - 201860 of 207726 results
  1. Instrument and Method for Forming Three-Dimensional Ultrasound Images of the Brea

    SBC: OPTOSONICS, INC.            Topic: NCI

    High Definition Ultrasound for Mammography Abstract We propose to develop High Definition Ultrasound (HD-US) based on a hemispherical synthetic aperture and backscattered sonic waves. This configuration will produce direct three-dimensional maps of ultrasound reflectivity of breast tissues, and will display higher signal-to-noise, reduced speckle and greater spatial resolution compared to ultra ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Technology Enabled Specialty Pharmacy for Oral Oncology

    SBC: MedicaSafe Inc            Topic: NCI

    DESCRIPTION (provided by applicant): This SBIR Phase I application proposes development of the MedicaSafe ChemoCareRx, a technology- enabled specialty pharmacy service for oral oncology patients built around MedicaSafe's proprietary Medication Therapy Optimization (MTO) technology. The increased use of oral oncology chemotherapy regimens has led to a paradigm shift in the treatment of cancer. ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Molecular Imaging of Macrophage Infiltration in Solid Cancers

    SBC: TARGESON, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Treatment of cancer accounts for an increasing level of healthcare expense although patient morbidity and mortality remain relatively high. Current methods for assessing the extent of immune cell infiltration into cancers require invasive biopsy procedures that cannot be done on the same tumor over time, thus precluding longitudinal tracking of immune responses ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Fecal DNA Testing for Colorectal cancer Screening

    SBC: GLC Biotechnology, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): This is the Phase I application of a SBIR project that will be devoted to develop a new fecal DNA test for CRC screening, which will utilize a new tri-marker panel discovered in our preliminary study. CRC is the seconddeadliest cancer in USA. The good news is that early detection along with resection is associated with a five-year survival rate of nearly 100%. ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Develop extremely-high-yield (5-10x conventional methods) tissue microarray techn

    SBC: ARRAY SCIENCE, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): We (Array Science, LLC) propose to perform detailed research and development of our patent-pending method and instrument for high-yield production of tissue microarrays (TMAs). Our approach to TMA production is novel inleveraging the liquid phase of standard histologic embedding media such as paraffin, and in so doing we achieve unprecedented levels of utilizat ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Transporter Targeted Platinum Drugs for Pediatric Tumor

    SBC: Apricity Therapeutics            Topic: NCI

    Project Summary/Abstract Childhood cancers remain a leading cause of death in children between 1 and 14 years of age. Of the childhood cancers, solid tumors are among the least curable. The goal of the proposed Phase I studies will be to develop targeted anti-cancer platinum analogs to treat three childhood tumors: osteosarcoma, rhabdomyosarcoma and neuroblastoma. In the U.S. about 1600 children a ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Synthesis and evaluation of novel kinase inhibitors as anti-metastasis agents for

    SBC: Epigen Biosciences, Inc.            Topic: NCI

    PROJECT SUMMARY Metastasis is a key factor for poor prognosis in cancer patients. Ovarian cancer is the fifth most common gynecological cancer causing significant mortality among women. Breast cancer is the most common invasive cancer in women and the second-most common cause of death in American women. Triple negative breast cancer tends to be both unresponsive to chemotherapy and more aggressive ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. A Healthy Dining Worksite Program Contributing to Healthier Eating in Restaurants

    SBC: ACCENTS ON HEALTH, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The economic and social costs related to obesity and other diet-related conditions (e.g., several forms of cancer, heart disease, type two diabetes, and more) are extensive. The worksite setting represents a channel through which hundreds of millions of Americans can be reached through tools and education that support healthier lifestyles. An important and ofte ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. A Novel Antibody Drug Conjugate for Metastatic Renal Cancer Treatment

    SBC: CENTROSE LLC            Topic: NCI

    Project Summary The incidence of renal cell cancer has been rising steadily and for those that have tumor recurrence after surgery, the prognosis is generally poor. In 2013 an estimated 65,150 new cases and 13,680 deaths will be attributed to renal cancerin the United States. Renal cancer is the most common malignancy of the adult kidney and accounts for 2-3% of all adult malignancies. Of these, 3 ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. New High Throughput Anti-Tumor Drug Screening System

    SBC: Vivo Biosciences Inc            Topic: NCI

    DESCRIPTION (provided by applicant): This SBIR project is focused to develop, validate and commercialize an advanced high-throughput anti- tumor drug screening platform (HTS) which employs a new 3D HuBioGEM assay technology. Preclinical drug screening is commonly performed using biochemical and cell-based assay systems. In recent years, more relevant 3D spheroid models have been developed using mi ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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