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Award Data

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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201891 - 201900 of 207699 results
  1. Targeted Theranostics for Metastatic Melanoma

    SBC: RADIOMEDIX, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): The American Cancer Society reports that death rates for melanoma have been rising in the United States for the past 30 years. It is one of the more common cancers in population younger than 30, and the most common cancer in adults ages 25 to 29. One characteristic of metastatic melanoma cells that is recognized as a potential target for new therapies is their ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Intravesical Chitosan IL-12 Therapy in an Orthotopic Mouse Bladder Cancer Model

    SBC: SCION CARDIO-VASCULAR, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): This SBIR project brings together the skills and resources of laboratories at Scion Cardio-Vascular Inc. (Scion C-V), Loma Linda University, and North Carolina State University to advance a new signaling molecule treatment for superficial bladder cancer. This treatment delivers the cytokine Interleukin 12 (IL-12) to the bladder wall using Scion C-V's muco ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Integrated System for FFPE Sample Preparation

    SBC: COVARIS, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Many samples taken from individuals and animals are stored by treating them with chemical, formalin, and then encasing them in paraffin or wax; these are called formalin fixed paraffin encased (FFPE) samples. Usually this storage is very good for preserving them for observation under microscopes, but it presents some problems in terms of analysis of their DNA. ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Dampening CAR therapy-induced cytokine storm with anti-GM-CSF antibodies

    SBC: CELDARA MEDICAL, LLC            Topic: NCI

    DESCRIPTION (provided by applicant): The long-term aim of this project is to reduce or eliminate the serious adverse events associated with cellular immunotherapy used to treat cancer. The current impressive efficacy of chimeric antigen receptor (CAR) T cell therapies is often accompanied by a well-known toxicity stemming from the large release of cytokines from activated immune cells, known as a ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. STING-Activating GM-CSF Secreting Allogeneic Pancreas Tumor Cell Vaccine Therapy

    SBC: ADURO BIOTECH            Topic: NCI

    DESCRIPTION (provided by applicant): The incidence of pancreatic adenocarcinoma (PDA) is gt 45,000 cases per year in the US and is increasing. While new chemotherapy regimens such as Abraxane and FOLFIRINOX extend overall survival, none offer the promise of long-term disease-free survival. We submit that immunotherapy can be an effective and durable therapeutic option for PDA. Here we extend both ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Treatment of non-small cell lung cancer with a CCL14 monoclonal antibody

    SBC: ONCOFACTOR CORPORATION            Topic: NCI

    DESCRIPTION (provided by applicant): Lung cancer is the most prevalent cancer worldwide and responsible for the most cancer deaths in the United States. Existing therapies include surgery, radiation, or chemotherapy to kill the tumor cells, but these options are not adequate for the vast majority of patients. Thus, there is a significant need to develop new therapeutic approaches. One of the most ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. A protein based strategy to reverse bone marrow failure resulting from radiation

    SBC: Marrowsource Therapeutics International LLC            Topic: NCI

    DESCRIPTION (provided by applicant): Bone marrow failure is also a frequent iatrogenic side-effect of radiotherapy and chemotherapy. Bone marrow failure can be caused by whole body exposure to even low doses of radiation. Strong radiation or chemotherapy can destroy metastatic cancers that have spread around the body but these aggressive treatments can end up bone marrow failure resulting in killi ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Immunotherapy for Brain Cancer

    SBC: MAPP BIOPHARMACEUTICAL, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): Glioblastoma is the most common primary brain tumor in adults. While many patients achieve disease remission following treatment with surgical resection, radiation therapy and chemotherapy, this remission is brief andinvariably followed by tumor recurrence and progression. The failure to offer durable therapies to patients with glioblastoma reflects the comple ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Multiplexed Mapping of Immune Infiltrates

    SBC: PROGNOSYS BIOSCIENCES, INC.            Topic: NCI

    DESCRIPTION (provided by applicant): New technologies are needed to enable the molecular characterization of the complex relationship between the immune system and cancer. This proposal aims to apply a novel approach to high-dimensional analysis of cancersamples, in order to determine if it can help to elucidate the interactions between the immune system and cancers, and ultimately to correlate t ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Using 3d bioprinting for Nipple Areola Complex (NAC) reconstruction

    SBC: TEVIDO BIODEVICES, INC.            Topic: NCI

    TeVido Project Summary/Abstract Globally, in 2010, there were slightly more than 1 million incidences of breast cancer. In the US ~200,000 women are diagnosed with breast cancer annually and nearly 40% will undergo mastectomies, full removal of the breast.In the US in 2010, more than 93,000 breast reconstructions were performed due to cancer. Patients with loss of the nipple areola complex (NAC) f ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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