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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201911 - 201920 of 207712 results
  1. Self-Digitization Microfluidic Device for Digital PCR

    SBC: LAMPROGEN INC            Topic: NIBIB

    DESCRIPTION (provided by applicant): This SBIR Phase I project will determine the feasibility of using Self-Digitization (SD) microfluidic technology as a commercially competitive nucleic acid quantification (NAQ) platform. Quantification of nucleic acids(both DNA and RNA) is utilized in various fields including general research, biomedical research, and clinical diagnostics, with specific applica ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. ANTIMICROBIAL COPPER ALLOY COATINGS FOR CONTACT ENVIRONMENTS

    SBC: MesoCoat            Topic: NIBIB

    DESCRIPTION: This Small Business Innovation Research Phase I project shows great intellectual merit. The antimicrobial properties of copper-based alloys continue to be a topic of research interest, and there are no current publications detailing the mechanical properties, corrosion resistance, and anti-microbial characteristics of copper-based alloy bi-layers. Pending a successful Phase I research ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Advanced Manufacturing Process for High Performance MRI Contrast Agents

    SBC: LUNA INNOVATIONS INCORPORATED            Topic: NIBIB

    DESCRIPTION (provided by applicant): Contrast-enhanced magnetic resonance imaging is widely used for non-invasive diagnosis of a variety of diseases. However due to the intrinsic properties of existing gadolinium-chelate contrast agents, there exist clinical needs of improved MRI contrast agents that render extended circulatory half-life enabling blood pool imaging with favorable biodistribution a ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. A Portable, Self-Contained Nucleic Acid Extraction and Storage System for POC Tes

    SBC: AI BIOSCIENCES, INC.            Topic: NIBIB

    DESCRIPTION (provided by applicant): This SBIR Phase I proposal aims to develop and commercialize a portable, easy-to-use system for nucleic acid preparation for effective molecular diagnostics in low-resource settings (LRS). The technology will also aid in the monitoring of treatment response for patients of global diseases such as AIDS, malaria, and tuberculosis. Because a reliable and reproduci ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Optical small animal imaging unit for quantification of bacterial infections

    SBC: IN VIVO ANALYTICS, INC.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Bacterial infections impose a costly health burden worldwide which is compounded by the alarming increase of multi-drug resistant bacteria, and many of these infections are in the urogenital tract. Urogenital tract infections (UTI) afflict mor than 250 million adults and children worldwide each year. However, pharmaceutical companies tasked with developing the ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Tracking cardiac engraftment and viability of MiPSC by MRI

    SBC: Bell Biosystems, Inc.            Topic: NIBIB

    DESCRIPTION (provided by applicant): The goal of this proposal is to demonstrate the effectiveness of using magneto-endosymbionts for MRI tracking of transplanted iPS cells in the myocardium. MRI is an important technique for visualizing implanted cells because it is non-invasive and provides high anatomical resolution of cell location. Existing MRI contrast reagents have several critical limitati ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Low cost electronic detection of molecular aggregation for rapid drug development

    SBC: Spectradyne LLC            Topic: NIBIB

    DESCRIPTION (provided by applicant): Nanoparticles are ubiquitous yet notoriously difficult to detect and measure-practical technologies for their characterization are effectively restricted to particles larger than about 500 nanometers in diameter. This limitation is acutely felt in the drug development industry: Because aggregate drug particles in parenteral formulations elicit a severe immune r ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. CellRaft Arrays for Single-cell PCR

    SBC: CELL MICROSYSTEMS INC            Topic: NIBIB

    DESCRIPTION (provided by applicant): Cell Microsystems is a start-up biotechnology company whose mission is to commercialize a cost effective platform for isolating and manipulating single, viable cells. The company's CellRaft(tm) technology is based on aunique cell array recently developed at the University of North Carolina (UNC) at Chapel Hill, and represents an ideal opportunity for the t ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. On-chip OCT for Ophthalmology applications

    SBC: Sinoora Inc.            Topic: NIBIB

    DESCRIPTION (provided by applicant): Sinoora Inc. proposes to develop an on-chip spectral domain-optical coherence tomography (SD-OCT) system for ophthalmic applications. Phase I will concentrate on demonstrating the passive optical components of the OCT system on a single chip. The passive components include a spectrometer, coupler and an interferometer. These on- chip components will then be int ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Enabling Metabolic Imaging Using Feedback Driven Magnetic Resonance Spectroscopy

    SBC: MILLIKELVIN TECHNOLOGIES, LLC            Topic: NIBIB

    DESCRIPTION (provided by applicant): Elevated levels of glycolysis are known to correlate with the presence and disease stage of various cancers. This phenomenon, known as the Warburg effect, provides the biological basis of Fluoro-Deoxyglucose Positron Emission Tomography (FDG PET) studies. FDG is taken up by the cell in a manner similar to glucose but then remains trapped in the cell for times e ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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