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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 201921 - 201930 of 207712 results
  1. An implantable hemodialyzer for treatment of End-Stage Renal Disease

    SBC: Silicon Kidney            Topic: NIDDK

    DESCRIPTION (provided by applicant): End-Stage Renal Disease (ESRD) affects just over 600,000 people in the United States and costs Medicare ~ 33 billion annually. In-center thrice-weekly hemodialysis is the most commonly performed treatment for ESRD, butit suffers from poor 5-year survival rates, reduced patient quality of life, and is costly. In contrast, daily-extended hemodialysis has demonstr ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Peptide-mediated apheresis for inflammatory bowel diseases

    SBC: AFFINERGY, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Inflammatory Bowel Disease (IBD), comprised primarily of ulcerative colitis (UC) and Crohn's disease (CD), is characterized by a chronic, uncontrolled inflammation of the intestinal mucosa. As many as 1.4 Million peoplein the United States and 2.2 Million people in Europe currently suffer from IBD, with 30,000 new cases reported each year in the US. Unfort ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Infrared Eyes

    SBC: EDEN MEDICAL, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Eden Medical, Inc. is pleased to submit this Phase 1 SBIR proposal to develop the Infrared Eyes (iREyes) imager system, an affordable and powerful mobile health (mhealth) tool for healthcare. The hand-held iREyes system will acquire both thermal and visible spectrum imagery to quantify healing via foot thermal indexing methodology. The iREyes will offer a use ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Cerberus-LNR: A Tethered Lightfield 3D Endoscope for Advanced Minimally Invasive

    SBC: XIGEN, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): The primary objective of this SBIR is to develop and pre-clinically evaluate a novel lightfield 3D endoscope, dubbed Cerberus-LNR, specially designed for laparoendoscopic single-site surgery (LESS), natural orifice translumenal endoscopic surgery (NOTES), and robotic LESS (R-LESS) (hereafter LNR) procedures. The miniature Cerberus-LNR lightfield 3D endoscope co ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Wearable Monitor for Recording the Activity of Brown Adipose Tissue

    SBC: MMTC, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Brown Adipose Tissues (BAT) are tissues that when activated become metabolically active and take calories from normal white fat and burn them. Safe methods for creating and activating (BAT) would therefore be of great value in fighting obesity, a leading preventable cause of death with increasing prevalence in adults and children and one of the most serious pub ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. A novel biomaterial-based therapy to prevent type 1 diabetes

    SBC: ONEVAX, LLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): Immune-mediated diseases such as type 1 diabetes (T1D), multiple sclerosis, rheumatoid arthritis, and systemic lupus erythematosis are reaching epidemic proportions in the US. T1D affects an estimated 3 million Americans, with more than 30,000 new patients diagnosed annually, resulting in roughly 15B in health care costs in the US each year. T1D is an autoimmu ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Flow sensing for an artificial pancreas

    SBC: FLUONIC, INC.            Topic: NIDDK

    DESCRIPTION (provided by applicant): The long term objective of diabetes treatment is to create an artificial pancreas to substitute for the role of the biological pancreas in patients. This artificial pancreas must constantly measure glucose and respondwith an appropriate dose of insulin and/or glucagon to achieve an artificial analog to homeostasis. However, the artificial pancreas is subject ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. A Panel-Based Approach to the Diagnosis of Genetic Nephropathies Utilizing Next G

    SBC: Nephropathology Associates, PLC            Topic: NIDDK

    DESCRIPTION (provided by applicant): There are currently mutations in over 200 genes that have been described to cause kidney disease. Current strategies for diagnosis of genetic kidney disease are extremely costly and time consuming. We aim to develop a comprehensive next generation sequencing panel that can simultaneously test for all currently described kidney- associated gene mutations at a lo ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Magnetic Tracking and Orientation of Imaging Endoscopic Capsules

    SBC: Koronis Biomedical Technologies Corp.            Topic: NIDDK

    DESCRIPTION (provided by applicant): Prior to the advent of capsule endoscopes (CE), imaging and examination of the small bowel was difficult. Today, a patient swallows the capsule with an imaging camera, which is then carried passively through the gastrointestinal (GI) tract by peristalsis. The onboard camera captures images of the lumen wall several times per second over a 7-11 hour period, rela ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Development of a lasmiditan analogue for treatment of acute kidney injury

    SBC: Mitohealth, Inc            Topic: NIDDK

    DESCRIPTION (provided by applicant): The long-term goal of this project is to develop a safe and efficacious therapeutic small molecule for treatment of acute kidney injury (AKI). AKI results from diverse insults such as sepsis, ischemia-reperfusion (I/R)or nephrotoxicant exposure and nearly half of those who develop AKI do not survive. Since treatment remains largely palliative and survival rates ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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