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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202161 - 202170 of 207725 results
  1. HSV Immunotherapeutic Vaccine

    SBC: VICAL, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The overall goal of this Phase I STTR proposal from the University of Washington (UW) and Vical Incorporated is to advance a multivalent, plasmid DNA (pDNA) immunotherapeutic vaccine for HSV-2 through preclinical development up to point of a pre-IND meeting. This proposal will combine the expertise of the UW group, the leading HSV-2 research group in the world, ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Transgenic Goats Produced by Germ Cell Transplantation

    SBC: GTC BIOTHERAPEUTICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this proposal is to produce transgenic goats by manipulation of the male germ line through male germ cell transfection and transplantation. The goats will carry the gene for human growth hormone (rhGH) under the control of a mammary gland specific promoter such that the milk of transgenic females will be an efficient source of protein for purif ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Datalogger Development for Wheelchair Mobility Outcomes

    SBC: THREE RIVERS HOLDINGS, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Independent mobility is a key contributor to the quality of life and social participation of an individual with a physical disability. With decreased mobility, there is usually an associated increased risk of social isolation, unemployment, and other health problems, such as obesity, cardiovascular disease, and pressure ulcers. Unimpaired individuals on fitne ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. AEGIS: A Pixel-array Readout IC for Gamma-ray Imaging

    SBC: Augustine Engineering            Topic: N/A

    DESCRIPTION (provided by applicant): CdZnTe arrays are promising detectors for improving nuclear medicine imaging, but existing CdZnTe cameras have limited spatial resolution and small numbers of pixels (space bandwidth product = SpBW). We show that major performance improvements will require high SpBW (>10A5) and small pixels (high resolution). The best approach to obtaining high SpBW detectors i ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Treatment of Gastroparesis with Multi-Channel Pacing

    SBC: Gi Stimulation, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The goal of this project is to investigate the safety and efficacy of multi-channel gastric electrical stimulation (MGS) in the treatment of patients with diabetic gastroparesis refractory to standard medical therapy. Previous animal studies have shown that appropriate multi-channel electrical stimulation of the stomach will: a) entrain gastric myoelectrical a ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Real Time Risk of Mortality in Critically III Children

    SBC: Multivariate Algrithms, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): The most important function of a pediatric intensive care unit (PICU) is to provide advanced computerized monitoring capabilities to clinicians to evaluate the clinical status of patients and to track their response to a wide range of interventions. We hypothesize that integrating and analyzing multiple, clinically important variables as: a. real time conti ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Hydronic, High-Speed, Focal Thermal Stimulator

    SBC: ALA SCIENTIFIC INSTRUMENTS INC            Topic: N/A

    DESCRIPTION (provided by applicant): Cloning of hot and cold thermal receptors has advanced the understanding of the molecular basis of thermal sensation. Two (2) important remaining questions to be addressed are the identification of additional thermal receptor genes and the elucidation of the mechanism(s) that enable the receptor proteins to alter gating properties in response to changes in temp ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Feasibility study of a double fiber bundle dialyzer

    SBC: MIRIMEDICAL, LLC.            Topic: N/A

    DESCRIPTION (provided by applicant): Efficiency of hemodialysis is currently limited by dialyzer technology. Although new membranes with large surface areas have been developed, the increase in delivered treatment is only marginal. Double dialyzer therapies have been shown to be superior to standard high efficiency/ high flux dialysis treatments; however implementation of double dialyzer thera ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. A 3-D Robot Design to Overcome Arm Dysfunction in Stroke

    SBC: LAM DESIGN MANAGEMENT, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Disturbances in movement coordination are the least well understood but often the most debilitating with respect to functional recovery following stroke. These deficits in coordination are expressed in the form of abnormal muscle synergies and result in limited and stereotypic movement patterns that are functionally disabling. The result of these constraints i ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. A Worldwide Research Network of Dynamic Cardiac Images

    SBC: HEART IMAGING TECHNOLOGIES, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): This is a Phase I of a fast-track STTR application submitted in response to Program Announcement PA-03-001 ("Knowledge Integration across Distributed Heterogeneous Data Sources"). We propose a collaborative effort between Heart Imaging Technologies, LLC (HeartIT) and Duke University's Cardiovascular Magnetic Resonance Center (DCMRC). The goal of the collaborati ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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