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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202161 - 202170 of 207725 results
  1. Vaccine Adjuvant for Rapid Tolerance Induction in Allergy Patients

    SBC: TRIA BIOSCIENCE CORP.            Topic: NIAID

    DESCRIPTION (provided by applicant): Allergy is a major cause of illness and disability with an estimated 40-50 million people afflicted in the US alone. AIT provides long-term benefits for the patient and its need for optimization creates a compelling business opportunity. There is a very strong rationale to develop GLA for allergy based on its superior drug profile to MPL, a related TLR4 agonist ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Vaccine Adverse Event Reporting System (VAERS) Application for Mobile Devices

    SBC: Global Health Data Systems, LLC            Topic: N/A

    A mobile computing application will be developed for Apple iOS and Google Android based mobile devices. This application will be targeted towards healthcare providers who make routine use of mobile devices in their daily work. The application will be capable of capturing all information required for submission to the Vaccine Adverse Event Reporting System (VAERS) and securely transmitting the info ...

    SBIR Phase II 2013 Department of Health and Human ServicesCenters for Disease Control and Prevention
  3. VACCINE AGAINST HAEMOPHILUS INFLUENZAE TYPE B

    SBC: Synergen Inc            Topic: N/A

    THIS RESEARCH WILL LEAD TO THE DEVELOPMENT OF A VACCINE THAT CAN BE USED TO PROTECT YOUNG CHILDREN AGAINST INFECTIONS CAUSED BY HAEMOPHILUS INFLUENZAE TYPE B (HIB). THE VACCINE WILL BE BASED ON THE PILI THAT FACILITATE THE ORGANISM'S ADHERENCE TO THE NASOPHARYNGEAL EPITHELIUM. ANTIBODIES PRODUCED IN RESPONSE TO THE VACCINE WILL BIND TO HIB PILI, PREVENTING ADHERENCE AND COLONIZATION, AND THEREBY L ...

    SBIR Phase I 1989 Department of Health and Human Services
  4. Vaccine Against Primate Immunodeficiency Retroviruses

    SBC: Allergene            Topic: N/A

    SIV infection of rhesus macaques serves as a valuable model for HIV infection in humans. Both virusthrough the CD4 T-lymphocyte receptor and are infectious and cytopathic for CD4+ T-lymphocytes and mviruses are genetically closely related: SIV shares approximately 50 percent homology with HIV-1 andhomology with HIV-2. In SIV- infected rhesus macaques, as in HIV-infected humans, a predominantly asi ...

    SBIR Phase I 1995 Department of Health and Human Services
  5. Vaccine Approaches to Treatment of Hepatitis C Infection

    SBC: Cytel Corp.            Topic: N/A

    The overall aim of our studies is to derive a potential HCV vaccine, based on the induction of HCV-To do so, we will identify a synthetic formulation composed of at least two A2-restricted CTL epitopconserved regions of the HCV genome. Such formulation will also contain universal T helper epitopesdemonstrated to be efficacious in inducing specific A2-restricted CTL responses in vivo, utilizing Hmi ...

    SBIR Phase I 1995 Department of Health and Human Services
  6. Vaccine Approaches to Treatment of Hepatitis C Infection

    SBC: Cytel Corp.            Topic: N/A

    The overall aim of our studies is to derive a potential HCV vaccine, based on the induction of HCV-To do so, we will identify a synthetic formulation composed of at least two A2-restricted CTL epitopconserved regions of the HCV genome. Such formulation will also contain universal T helper epitopesdemonstrated to be efficacious in inducing specific A2-restricted CTL responses in vivo, utilizing Hmi ...

    SBIR Phase II 1998 Department of Health and Human Services
  7. VACCINE: AUTO-IMMUNE DESTRUCTION OF TRANSPLANTED ISLETS

    SBC: CORIXA CORPORATION            Topic: N/A

    Not Available The goals of this program are to design, fabricate and test a readout integrated circuit (ROIC) specifically designed for use with Quantum Well Infrared Photodetector (QWIP) arrays and to incorporate the advanced signal processing requirements needed for Third Generation FLIRs. QWIP photodetector arrays are fabricated from large bandgap materials (GaAs/AIGaAs) which are easily grown ...

    SBIR Phase I 1999 Department of Health and Human Services
  8. VACCINE DELIVERY SYSTEM FOR LIVE ROTAVIRUS VACCINES

    SBC: Secretech, Inc.            Topic: N/A

    THE LONG-TERM OBJECTIVE OF THIS STUDY IS THE DEVELOPMENT OF AN EFFECTIVE DELIVERY SYSTEM FOR A LIVE HUMAN ROTAVIRUS VACCINE. TO AVOID THE INACTIVATION OF VIRUS BY GASTRIC ACID, DIFFERENT BUFFERS ARE BEING GIVEN BEFORE VACCINATION IN CURRENT VACCINE TRIALS. THIS PROJECT FOCUSES ON THE IMPROVEMENT OF THIS TIME- AND COST-CONSUMING PRESENT VACCINEADMINISTRATION PROCEDURE. TO EVALUATE THE EFFICACY OF D ...

    SBIR Phase II 1992 Department of Health and Human Services
  9. VACCINE DELIVERY SYSTEM FOR LIVE ROTAVIRUS VACCINES

    SBC: Secretech, Inc.            Topic: N/A

    N/A

    SBIR Phase I 1990 Department of Health and Human Services
  10. Vaccine discovery for Burkholderia via protection screen

    SBC: MACROGENICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Glanders is a severe disease that has already been used as a bioweapon. It is naturally an equine disease but can be administered by aerosol for efficient human infection. Even if quickly diagnosed as Burkholderia mallei and treated, antibiotics do not control infections well. No vaccine has been developed, yet is a rational component of any plan for defense. I ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
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