You are here

Award Data

For best search results, use the search terms first and then apply the filters
Reset

The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202171 - 202180 of 207725 results
  1. Optimization of an innate immune stimulating adjuvant for an HIV DNA vaccine

    SBC: ORLANCE, INC            Topic: NIAID

    Abstract There is a growing consensus that protection against HIV infection will require BOTH antiviral antibody responses as well as polyfunctional CDand CDT cells with potent lytic activityTo stimulate the breadthpotencyand rate of response requiredProfectus Biosciences intends to utilize its platform technologies based on DNA vaccines combined with genetic adjuvantsAs a step in that directiona ...

    SBIR Phase II 2018 Department of Health and Human ServicesNational Institutes of Health
  2. Development of a rapid response nucleic acid vaccine strategy for coronavirusepidemics

    SBC: ORLANCE, INC            Topic: NIAID

    ABSTRACT In response to the emerging COVID-19 (SARS-CoV-2) pandemic, this supplement proposal to R44 AI138733- 01 will leverage our cutting-edge nucleic acid vaccine strategies, some of which that were developed under this parent grant. Here, we request supplement funding to develop candidate COVID-19 DNA and RNA vaccines expressing optimally designed immunogens for the SARS-CoV-2 spike protein. N ...

    SBIR Phase II 2019 Department of Health and Human ServicesNational Institutes of Health
  3. Universal Influenza A/B Vaccine

    SBC: ORLANCE, INC            Topic: NIAID

    Abstract Universal influenza vaccines should be possible if conserved antigens of influenza are effectively targeted and effective antiviral immune responses are generated against those antigens. DNA vaccination is an appealing approach for delivering universal influenza vaccines, however, natural immune responses to conserved influenza antigens are typically weak and most DNA vaccines tested in h ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  4. Universal Influenza A/B Vaccine

    SBC: ORLANCE, INC            Topic: NIAID

    Abstract Universal influenza vaccines should be possible if conserved antigens of influenza are effectively targeted and effective antiviral immune responses are generated against those antigens. DNA vaccination is an appealing approach for delivering universal influenza vaccines, however, natural immune responses to conserved influenza antigens are typically weak and most DNA vaccines tested in h ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Next Generation Gene-Gun Delivered DNA and RNA Immunotherapeutic Vaccines for Melanoma.

    SBC: ORLANCE, INC            Topic: NCI

    PROJECT SUMMARY Orlance has developed a next-generation Gene Gun (MACH-1 GG) that efficiently delivers DNA and RNA into epidermal cells, leading to robust immune responses. Sequencing of tumors from individual patients has led to the identification of personalized neoantigens that could be targeted with cancer vaccines. However, technologies that can effectively deliver these cancer neoantigens an ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Clinic-Ready MACH-1 Gene Gun for delivery of a universal influenza DNA vaccine

    SBC: ORLANCE, INC            Topic: NIAID

    PROJECT SUMMARY Orlance has developed a lead universal influenza (UFlu) DNA vaccine to address the need for a vaccine that can protect from annual influenza and the emergence of new variants that could cause future pandemics. Our UFlu vaccine is a multi-dose vaccine designed to induce systemic and mucosal immune responses that can prevent transmission and minimize disease from currently circulatin ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. Adaptive Relay Settings for Wide Area Coordination of the Power Grid

    SBC: SYNCHROGRID, INC.            Topic: 07a

    The reliable operation of the electrical power grid is foundational for our society, and it requires an active protection scheme to guard against failures. Protective relays play a critical role in grid protection, but their configuration is challenging and is growing more difficult with the grid’s increasing complexity. A well-engineered, predictable relay configuration (i.e., relay settings) m ...

    SBIR Phase I 2021 Department of Energy
  8. High Power RF Windows for Accelerator Applications

    SBC: CALABAZAS CREEK RESEARCH, INC.            Topic: 14e

    High power RF windows are failing due to single surface multipactor. A more effective and robust technique is required to address this problem. This program will investigate two approaches for addressing multipactor failure in high power windows. The first will explore improved methods for depositing surface films to reduce secondary electron emission. The second approach will investigate changes ...

    STTR Phase I 2010 Department of Energy
  9. High Current Density Long Life Cathodes for High POwer RF Sources

    SBC: CALABAZAS CREEK RESEARCH, INC.            Topic: 64e

    The power that can be produced by klystrons and other RF devices is often limited by the current emission density that can be extracted from the cathode. Operation of existing cathodes at high current density leads to dramatically reduced lifetime. Long life cathodes operating at high cur

    SBIR Phase I 2010 Department of Energy
  10. Development of a 2 MW CW Waterload for Electron Cyclotron Heating Systems

    SBC: CALABAZAS CREEK RESEARCH, INC.            Topic: 56b

    Gyrotrons are being developed for ITER and other fusion systems that produce 2 MW CW of RF power for electron cyclotron heating. Currently there are no waterloads available to test gyrotrons at this power level. The U.S. also is responsible for providing 1.5 MW loads and 2.0 MW loads for ITER. Calabazas Creek Research, Inc. developed prelimnary designs in Phase I that efficiently distrib

    SBIR Phase II 2010 Department of Energy
US Flag An Official Website of the United States Government