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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202181 - 202190 of 207725 results
  1. Automated Test of Word Recognition- Phase II

    SBC: AUDIOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): Over 5 million word recognition tests are administered annually by audiologists in the United States with an associated cost of more than $100 million. These tests are currently performed manually by highly trained audiologists. This application describes the Phase II development of automated clinical speech recognition tests using clinical test recordings and ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Novel Transcription Profiling in Toxicologic Assays

    SBC: Genpathway, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A common reason for failure of drugs in development or their removal from the market is hepatotoxicity. This is due to the many adverse drug reactions and drug-drug interactions that result from drug metabolism, enzyme induction or inhibition of drug metabolizing enzymes. Unfortunately, effective in vitro and in vivo approaches to accurately predict hepatotoxi ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Reagents for Preparing Structure-Free DNA and RNA

    SBC: TRILINK BIOTECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Secondary structure in single-stranded ONA and RNA is a significant barrier to the efficient hybridization of short oligonucleotide probes. While some probes to a given target hybridize efficiently, other probes to the same target may not hybridize at all. Use of longer probes, on the order of 60 nucleotides in length, is one way to overcome this problem. Unfor ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Production of High Specific Activity Lutetium-177

    SBC: ALPHAMED, INC            Topic: N/A

    DESCRIPTION (provided by applicant): A separation method will be tested and evaluated to determine the feasibility of providing no carrier added lutetium-177 (Lu-177) for use in radiotherapeutic applications. An indirect method will be used to produce Lu-177 (neutron capture followed by decay). Separation of the Lu-177 from the target material will enable us to provide carrier-free Lu-177 suita ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Polarized Xenon Production: Powerful Narrowed Laser

    SBC: XEMED LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Both hyperpolarized xenon and helium have demonstrated utility in lung imaging and quantifying lung disease. In contrast to helium, however, hyperpolarized xenon has a high solubility in fluids and tissues and a characteristic chemical shift, revealing its microscopic environment in dissolved-phase imaging. An imaging protocol to investigate dissolved-phase ima ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Optical Tomography for Diagnosis of NEC

    SBC: Photon Migration Technologies Corp.            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I study explores the feasibility by which the technique of dynamic near-infrared optical tomography (DYNOT) can be employed as an accurate, noninvasive tool to assess tissue perfusion of small bowel in neonatal patients at risk for Necrotizing Enterocolitis (NEC). NEC is a disease process that primarily affects premature infants a week to ten days ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Magnetic Resonance Electrical Impedance Mammography

    SBC: Wollin Ventures, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A novel breast imaging approach is proposed to measure and map both magnetic resonance and complex permittivity properties of the breast. The new technology is based on intellectual property owned by Wollin Ventures Inc. that demonstrates the potential of simultaneous magnetic resonance mammography (MRM) and electrical impedance scanning (EIS) of the breast wit ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. High Purity Amphotericin B: A Safer Antimycotic in AIDS

    SBC: CUMBERLAND PHARMACEUTICALS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Cumberland Pharmaceuticals and the University of Mississippi Mycotic Research Centers' long-term goal will be to improve anti-fungal pharmacotherapy particularly for patients with human immunodeficiency infections (HIV). We are jointly developing a high purity amphotericin B (AmB HP) product for intravenous administration. The nominal purity of AmB HP is 95%; ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Assessment of Altered Function in Diabetic Bladder

    SBC: Neurotron, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Diabetic bladder dysfunction (DBD) or diabetic cystopathy is one of the most common and debilitating complications of diabetes mellitus (DM) affecting well over 50% of the patients with either type I or type II diabetes. DBD could affect both the filling and voiding function of the bladder leading to urinary incontinence, poor emptying, high post void residual ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Improved Acoustic Detection of Coronary Blockages

    SBC: SONOMEDICA, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Heart disease is the leading cause of death for both women and men in the industrial world and despite the fact that early detection of CAD allows for successful and cost effective treatment of the disease, only 20% of CAD cases are diagnosed prior to a heart attack. Based on principles pioneered by the PI, SonoMedica Inc. has developed a device that can non ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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