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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202201 - 202210 of 207728 results
  1. Oral delivered bone building therapy for osteoporosis

    SBC: OsteoGeneX Inc            Topic: NIAMS

    DESCRIPTION (provided by applicant): The osteoporosis market is still in demand for new therapeutics due to the lack of safe orally available bone building drugs. Currently, parathyroid hormone (PTH; FORTEOTM) and its analogs are the only bone building therapies available yet they capture only 8% of the osteoporosis market due to significant dosing and safety limitations. OsteoGeneX is developing ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  2. Establishing BRM Polymorphisms as Predictive Biomarkers for Lung Cancer Risk

    SBC: RIVANNA MEDICAL, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Despite being correlated to poor health outcomes, emergency department (ED) overcrowding occurs several times per week in 90% of all EDs in the US. A primary contributor to ED overcrowding is high demand for radiology services (i.e. X-rays), which are relied upon for diagnosis of bone fractures in 7.2 million non-time- sensitive suspected bone fracture patients ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  3. HyCart- Biologic Cartilage Resurfacing with a Functional Osteochondral Implant

    SBC: ARISTON MEDICAL , INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): The goal of this proposal is to develop the osteochondral HyCart product to enable resurfacing of entire knee joint compartments and repair of defects up to 20cm2 in articular cartilage of the knee joint. The HyCart implant will be custom-shaped to the defect and consist of engineered cartilage functionally interdigitated to nano-hydroxyapatite (nHA). As articu ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  4. Biofidelic Slip-Testing Device for Measuring and Analyzing Shoe-Floor Friction

    SBC: CROSSROADS CONSULTING LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Falling accidents are among the largest and fastest growing sources of occupational injuries. Despite slips representing a plurality of all falling accidents, the technology used to assess the slipperiness of shoe andfloor surfaces has remained relatively stagnant over the past two decades. A major limitation in existing slip-testers is that the under-shoe co ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  5. A novel anti-scar peptide for cutaneous wound repair

    SBC: SCARLESS LABORATORIES INC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Cutaneous fibrosis (scarring) affects up to 100 million patients per year as a result of 55 million elective operations and 25 million operations after trauma. Besides concerns of cosmesis, scarring can have significantfunctional sequel. Overall, scar prevention strategies for skin are minimally effective. Currently available techniques focus on reducing the ap ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  6. Multivalent Growth Factor Conjugates to Accelerate Wound Neovascularization in El

    SBC: C-MOTION, INC.            Topic: NIAMS

    DESCRIPTION (provided by applicant): Orthopaedic disorders are a leading cause of disability in the U.S., with arthritis and/or spine problems adversely affecting quality of life fo more than 20% of adults. With an aging population, the rate of disabilityfrom orthopaedic disorders has been increasing steadily. While advances in diagnostic imaging (including CT, MRI and ultrasound) have greatly imp ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  7. Adipokine Secretion Enhancer Synthetic Organic Drug Discovery in Human Adipocytes

    SBC: Panorama Research Incorporated            Topic: NIAMS

    DESCRIPTION (provided by applicant): The overall goal of this project is the preclinical development of a novel Rho kinase inhibitor (TRX-101) as a new therapy for scleroderma/systemic sclerosis (SSc). SSc is a chronic disease of unknown etiology characterized by severe and often progressive fibrosis affecting the skin and in some cases internal organs. Since there is no approved anti-fibrotic dru ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  8. Targeting ATAP-mediated Apoptosis in Treatment of Prostate Cancer

    SBC: FLUIDIC TOOLS, LLC            Topic: NIAMS

    DESCRIPTION (provided by applicant): The lifetime of total joint replacement prostheses has been limited by three factors: oxidative degradation, wear and mechanical failure of its polyethylene components. In recent years, the problem of wear and oxidationresistance has been addressed. Radiation crosslinking substantially increases the resistance of polyethylene to particulate wear. Studies have s ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  9. COMPUTERIZED CROSS-CULTURAL COMPETENCY ASSESSMENT PROGRAM FOR HEALTH ORGANIZATION

    SBC: NESHER TECHNOLOGIES INC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Arthritis is a heterogeneous disease of the 'whole joint', whereby different combinations of proteolytic enzymes are active in different patient subpopulations leading to progressive joint degeneration. Upfront identification and stratification is critical for appropriate intervention with specific inhibitors, several of which are being evaluated in ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
  10. Hollow Fiber Catheter for Drug Delivery into the Prostate

    SBC: PROGENITEC INC            Topic: NIAMS

    DESCRIPTION (provided by applicant): Chronic non-healing wounds continue to pose great challenges to clinicians. It is estimated that there are 1.1-1.8 million new chronic wound patients each year and approximately 8 million Americans suffering from chronic wounds. To make the situation worse, chronic wounds often predispose the patients to infection. The problem is compounded by the lack of effe ...

    SBIR Phase I 2013 Department of Health and Human ServicesNational Institutes of Health
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