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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202231 - 202240 of 207699 results
  1. Shape Recovery Polymer Nanocomposites

    SBC: COMPOSITE TECHNOLOGY DEVELOPMENT, INC.            Topic: AF04143

    The primary focus of the proposed Phase II effort is to further understand the BiPolymeric™ phenomenon, thus enabling increased deployment capabilities, and the engineering of BiPolymeric™ solid-state actuators and mechanisms suitable for practical use. The proposed effort includes material development focused on enhancing the BiPolymeric™ effect through the incorporation of nano-reinforcem ...

    SBIR Phase II 2005 Department of DefenseAir Force
  2. Development of a human placental extract for the prevention of necrotizing enterocolitis in premature babies

    SBC: PLAKOUS THERAPEUTICS, INC.            Topic: NICHD

    PROJECT SUMMARY Necrotizing enterocolitis (NEC), an acute inflammatory necrosis of the intestinal tract, is the most common acquired gastrointestinal and surgical emergency for preterm very low-birth weight infants in the neonatal intensive care unit. Despite considerable advances in neonatal care, NEC remains a devastating disease (mortality rates range from 15% to 30%) that lacks a cure. Managem ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  3. Useful Life Remaining Models for Turbine Engine Hot Section Components

    SBC: ROTORDYNAMICS-SEAL RESEARCH            Topic: N03027

    A new integrated modeling and simulation capability is proposed to substantially improve the predictions of transient dynamic loads for gas turbine engines. These improved loads enable a improvement in the determination of useful life remaining for hot section components. This effort includes compiliation of the necessary software elements to generate a fully coupled, transient analysis for the ...

    SBIR Phase II 2005 Department of DefenseNavy
  4. Using Mobile Technology to Enhance MST Outcomes

    SBC: EVIDENCE-BASED PRACTICE INSTITUTE, INC.            Topic: 104

    PROJECT SUMMARY ABSTRACTEach yearover one million adolescents are arrestedmany more engage in other serious conduct problemsincluding binge drinkingillicit drug useand school drop outCollectivelythese problems result in enormous costs to individualsfamiliesand societyThe most effective interventions to address these problems are family basedwith a strong clinical emphasis on helping parents better ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  5. Generation of a zebrafish insertional mutation library

    SBC: ZNOMICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): At the present time it is not possible to rapidly and inexpensively obtain a vertebrate knockout in a gene of choice, or to readily perform whole genome forward genetic screening in a vertebrate. The goal of this P

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Pulse Water Strip of Tungsten Carbide HVOF Coatings and Chrome Plating on Landing Gear Components

    SBC: ENGINEERING AND SOFTWARE SYSTEM SOLUTIONS, INC.            Topic: AF071317

    ABSTRACT: Chrome plating has been utilized for Aircraft, Landing Gear, Engine and Propeller components for over half a century, and High Velocity Oxygen Fuel (HVOF) tungsten carbide (WC-Co, or WC-Co-Cr) coatings are currently being utilized for chrome replacement on many aerospace components and implemented on many non-aerospace applications. Aircraft, Landing Gear, Engine and Propeller componen ...

    SBIR Phase II 2012 Department of DefenseAir Force
  7. Ultra-High Frame-Rate Pixelated Direct Electron STEM Detector

    SBC: DIRECT ELECTRON, L.P.            Topic: 24a

    Multi-color electron microscopy (EM) is a powerful new technique for studying biological ultrastructure with selective lanthanide-ion tagging of specific components of interest. The technique is analogous to multi-color fluorescence microscopy, but at about 100× higher magnification. However, the current method for acquiring multi-color EM data based on energy-filtered TEM (EFTEM) requires high-p ...

    SBIR Phase II 2019 Department of Energy
  8. A Phase I/II Clinical Trial to Investigate Fucosylated Tregs in Prevention of GVHD

    SBC: TARGAZYME, INC.            Topic: 102

    DESCRIPTION provided by applicant Allogeneic hematopoietic stem cell transplant has the potential to cure various hematological malignancies and inherited disorders but is limited by treatment related mortality which in a majority of cases is directly related to Graft versus Host Disease GVHD Current therapy for GVHD involves prolonged immunosuppression with calcineurin inhibitors such as ...

    SBIR Phase II 2015 Department of Health and Human ServicesNational Institutes of Health
  9. Multi-Net Link-16 Receiver

    SBC: TrellisWare Technologies, Inc.            Topic: N091090

    In Phase I, TrellisWare configured a multi-net receiver architecture that would fit within SWaP constraints of single-net systems (retrofit into MIDS-LVT, MIDS-J). In addition, laboratory testing (with a brass-board configuration) confirmed that the performance of the multi-net architecture exceeds the performance of current/development single-net production hardware (MIDS-LVT, MIDS-J). For Phase ...

    SBIR Phase II 2011 Department of DefenseNavy
  10. Novel Mucosal Adjuvant for an HIV DNA Vaccine

    SBC: PROFECTUS BIOSCIENCES, INC.            Topic: NIAID

    DESCRIPTION provided by applicant Our primary approach to develop an effective prophylactic vaccine against HIV utilizes a novel immunogen called the Full Length Single Chain FLSC that consists of gp derived from HIV genetically linked via a amino acid linker to the D D domains of human CD When rhesus macaques were inoculated with versions of FLSC that contain CD derived from rhes ...

    SBIR Phase II 2016 Department of Health and Human ServicesNational Institutes of Health
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