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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202231 - 202240 of 207699 results
  1. Neural Activity Imaging and Sensing System Using Multifunctional Diamond Nanosens

    SBC: DUST IDENTITY, INC.            Topic: NIMH

    DESCRIPTION (provided by applicant): In this Small Business Innovation Research program, we will develop an optical imaging system that uses diamond nanosensors for high-speed parallel recording of neural activity in brain tissue in in vitro and in vivo animal models. The study of neural circuitry is one of the primary drivers in the development of effective treatments and extends our understandin ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. OnTrack> An Online Role-Playing Game

    SBC: C4 Innovations, LLC            Topic: NIMH

    DESCRIPTION (provided by applicant): Recent research on the treatment of first-episode psychosis has documented positive results and hope for better long-term outcomes for consumers and their families. In particular, the NIMH-funded RISE study (Recovery after an Initial Schizophrenia Episode) developed an innovative early intervention. Building on the RAISE project, the Center for Social Innovatio ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Robust Suicide/Reinjury Risk Models to Assess Healthcare Systems

    SBC: MARTINGALE RESEARCH CORPORATION            Topic: NIMH

    DESCRIPTION (provided by applicant): Recent research suggests that the most effective treatment of suicidal states occurs in the context of multi- level prevention initiatives within healthcare delivery systems. Such findings underscore the importance to create services that can address suicide and reinjury risks. While offering key services have been associated with reduced suicide rates, it is i ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Cognitive Training for ADHD Treatment using a Gaming Model

    SBC: Koronis Biomedical Technologies Corp.            Topic: NIMH

    DESCRIPTION (provided by applicant): In this phase I project, Koronis Biomedical Technologies (KBT) proposes to develop an electroencephalography (EEG) based neurofeedback video game to enable individuals to improve neurocognitive processes associated withAttention Deficit Hyperactivity Disorder (ADHD). Neurofeedback is a form of biofeedback in which real-time measures of brainwave activity are pr ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. Development of the Partner Pain Support Program

    SBC: GOALISTICS LLC            Topic: NINR

    Abstract Chronic pain occurs in a social context, frequently impacting couples in a committed relationship. Most couples have a reciprocal influence on one another. Partners of people with chronic pain are both affected by pain and may play a (positive ornegative) role in pain management. Depending upon their skills and knowledge, partners may interfere with or facilitate coping with chronic pain ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Development of novel, biophysically designed fluids for swallowing disorders

    SBC: Swallow Solutions, LLC            Topic: NINR

    DESCRIPTION (provided by applicant): Swallowing disorders, known as dysphagia, are associated with increased mortality and morbidity, including malnutrition, dehydration, pulmonary complications, and reduced quality of life. More than 18 million adults (and millions more children) suffer from dysphagia. Dysphagia commonly causes thin liquids (e.g., water, coffee) to be aspirated or misdirected int ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Bifunctional potassium-ATP channel opener and redox catalyst for therapy of spina

    SBC: RADIKAL THERAPEUTICS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Radikal Therapeutics (RTX) is developing a first-in-class cytoprotective small molecule (R-801) for the prevention of spinal cord injury (SCI) based upon the chemical fusion of 2 discrete chemical domains that: 1) target redox stress via a nitroxide spin-trap moiety, and 2) trigger the endogenous ischemic-preconditioning response via mitochondrial-selective K+ ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Novel Small Molecule Multi-targeted Ligands as Therapeutics for the Treatment of

    SBC: JASIN DISCOVERY SOLUTIONS, INC.            Topic: NINDS

    DESCRIPTION (provided by applicant): Spinal Muscular Atrophy (SMA), a common autosomal recessive motor neuron disorder is the leading genetic cause of infant mortality. SMA is caused by the loss of the survival motor neuron1 (SMN1) gene. SMN2, a nearly identical paralog, is present in all SMA patients but differs by a critical nucleotide that alters exon 7 splicing efficiency. This results in low ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Improved Electrode Material for Deep Brain Stimulation

    SBC: Epic Medical Inc.            Topic: NINDS

    DESCRIPTION (provided by applicant): In the United States, over 100,000 deep brain stimulation (DBS) devices have been implanted to date for treatment of basic tremor, Parkinson's disease and dystonia, and clinical trials are underway to evaluate indications for chronic pain, severe depression, migraines and dimentia. DBS devices belong to a class of devices called implantable electrical stim ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Development of self-delivering RNAi to evaluate PTEN as a therapeutic target to p

    SBC: BIOAXONE BIOSCIENCES, INC.            Topic: NINDS

    Project Summary Innovative drug/therapy combinations directed at multiple and proven therapeutic targets have the potential to dramatically improve outcomes after SCI. Studies on axon regeneration and recovery in rodents have revealed that the spinal cordis not hard wired and learning can occur in spinal cord circuits. Compounds that elicit axonal regeneration and sprouting help plasticity in th ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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