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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202241 - 202250 of 207728 results
  1. Activated hexosamines from chitin for production of important oligosaccharides

    SBC: ZUCHEM INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): UDP-GlcNAc and UDP-GalNAc comprise the core structures of glycans in glycoproteins and glycolipids. Oligosaccharides containing N-acetyl-hexosamines involved in various biological process, including microbial infection,toxin entry, cancer cell metastasis. They are the key building blocks for human milk oligosaccharides, blood antigens, and other important oligo ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. A Compact, High-power Terahertz Amplifier for DNP-NMR and EPR Spectroscopy

    SBC: BRIDGE 12 TECHNOLOGIES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): We propose to develop a compact, cost-effective Traveling Wave Tube (TWT) amplifier at 263 GHz with 50 W of peak power, 5 W of continuous wave power and 5% instantaneous bandwidth for application in Dynamic Nuclear Polarization (DNP) enhanced solid-state and solution-state NMR and Electron Paramagnetic Resonance (EPR) spectroscopy. With DNP, the inherently smal ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  3. Holographic Virtual Anatomy Table

    SBC: Third Dimension Technologies LLC            Topic: NIGMS

    Project Summary/Abstract Medical students long ago gave up robbing graves for corpses, but students still need access to anatomy resources. While availability of traditional resources (e.g. cadavers, animals, etc.) is dwindling, emerging virtual alternatives are revolutionizing the practice of medicine. Interest in virtual aids derives from decades of success in aviation and the military. These in ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  4. Targeted mutagenesis of plant genes by the CRISPR/Cas system

    SBC: PLANET BIOTECHNOLOGY, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): There is a clear need, in plants, for an efficient and practical system for targeted mutagenesis. Planet Biotechnology's interest is in using the tobacco species Nicotiana benthamiana as a factory for the economical production of human therapeutic proteins, including a recombinant Fc fusion protein for treatment of inhalational anthrax. The CRISPR/Cas sy ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  5. High Energy Rechargeable Battery as Emergency Power Supplies for Medical Assistiv

    SBC: NOHMS TECHNOLOGIES INC            Topic: NIGMS

    Project Summary NOHMs Technologies proposes to develop a novel Lithium-Sulfur (Li-S) battery system as a reliable emergency power source for assistive medical equipment. NOHMs Li-S battery can increase the energy delivery time in a power outage from 2 hours to 24 hours or more, while yielding a significant reduction in weight, size, and cost compared to existing emergency power supply systems. Li- ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  6. Lessons from Nature: Antifreeze Glycolipids for Cryopreservation of Mammalian Cel

    SBC: Cell & Tissue Systems, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Storage of cells for many researchers simply involves addition of 10% DMSO or similar cryoprotectants to cells in suspension, putting them in cryovials and slow cooling to subzero temperaturesf and storage in a mechanical or nitrogen cooled freezer or dewar. As long as viable cells are present upon thawing, cell yield may be a secondary consideration due to the ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  7. Selectively Absorbable Surgical Mesh for Hernia Repair

    SBC: POLY-MED, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): Hernia repair is one of the most frequently performed surgical operations in the United States with approximately 800,000 procedures performed annually. The vast majority of these repairs employ a tension- free repairtechnique which involves the use of synthetic surgical meshes. Existing mesh technology is designed to be of high strength to produce a perceive ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  8. Novel medical device for treatment of fungal nail infection

    SBC: DEVICEFARM, Inc.            Topic: NIGMS

    DESCRIPTION (provided by applicant): This proposal continues the proof-of-concept development and testing of a novel, safe, and effective treatment device for onychomycosis (nail fungal infection). While onychomycosis is considered a cosmetic problem, theinfected nail also becomes a persistent reservoir for infectious microbes that could lead to other significant medical problems. Over 35 million ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  9. Microfluidic Disposables and Instrument for a Single-Cell Western Blotting System

    SBC: ZEPHYRUS BIOSCIENCES, INC.            Topic: NIGMS

    DESCRIPTION (provided by applicant): The goal of this project is to provide a broadly available research tool that allows the direct measurement of protein expression heterogeneity through massively parallel, single-cell resolution Western blot analyses. This method promises to revolutionize diverse fields such as stem cell differentiation, drug discovery, and cancer biology by allowing researcher ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Toward a Complete Set of Germline Null and Modifiable Mutations in Drosophila

    SBC: GENETIVISION CORPORATION            Topic: NIGMS

    DESCRIPTION (provided by applicant): The overall goal of this proposal is to generate, maintain, and distribute a new collection of engineered Drosophila melanogaster stocks that will allow versatile manipulation of genes for which there is currently no mutant allele available. Using cutting edge CRISPR technology, this collection or 'kit' will represent a powerful new set of tools that ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
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