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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202241 - 202250 of 207726 results
  1. Quantitation Pulmonary Delivery of Therapeutic Protein

    SBC: Arizeke Pharmaceuticals, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Arizeke Pharmaceuticals, Inc. is focused on the pulmonary delivery of protein therapeutics (including antibodies) to treat pulmonary disease. Arizeke's technology provides a unique ability to deliver large therapeutic proteins into the lung parenchyma and interstitium and into the lymphatic drainage system. Examples of indications that can be targeted by this t ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Restoration of vestibular hair cells induced by AdMath1

    SBC: GENVEC, INC.            Topic: N/A

    Loss of vestibular hair cells can occur due to a variety of disorders and results in dysfunction of the vestibulo-occular reflex and loss of balance. Bilateral vestibular hypofunction due to aminoglycoside ototoxicity and other means is a devastating and currently untreatable chronic disorder because loss of vestibular hair cells is permanent. To date there is no prosthetic device such as a hearin ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Novel epoxide hydrolase inhibitor for stroke prevention

    SBC: Arete Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A major cause of morbidity and mortality is the progression of organ damage associated with cardiovascular diseases. For instance, the incidence of stroke and costs associated with stroke damage continues to have a devastating impact on public health despite numerous treatments aimed at cardiovascular risk factors. Recent findings indicate that increasing lev ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. Fiber Optic Array Based Bioluminesence Imaging

    SBC: Korima, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Bioluminescence imaging is a novel technique for visualizing biological processes within living animals. The cells or organism of interest are genetically modified to express luciferase, the enzyme that causes some insects, jellyfish, and bacteria to glow. Luciferase catalyzes a chemical reaction that generates light as one of its products. A highly sensitive ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Utility of a Novel Anthracycline Analog in Psoriasis

    SBC: GEM Pharmaceuticals            Topic: N/A

    DESCRIPTION (provided by applicant): Psoriasis is a common immune-mediated disease that affects approximately 2% of the US and European populations and significantly impacts the quality of life. T cells are recognized as primary mediators of the disease and new generation therapies aimed at eliminating reactive T cells or interfering with the immunologic cascade caused by their activation have bee ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. G-Protein Coupled Receptor Nanostructure Pharmaceutics

    SBC: Nanodisc, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Membrane proteins play critical functions in many if not most cellular and physiological processes. Single membrane proteins and their macromolecular assemblies are essential catalysts in the metabolism and conveyance of information and energy between cells and the external environment, between cellular compartments and in the interactions of cells with viral ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Life Belt CPR: Sternal Compression and Thoracic Constraint

    SBC: Deca-Medics            Topic: N/A

    DESCRIPTION (provided by applicant): In the United States, more than 250,000 persons annually experience out-of-hospital sudden cardiac death (SCD). However, few, approximately 4%, are revived with standard CPR and advanced life support interventions and survive to be discharged from the hospital. Successful restoration of cardiac function after SCD is dependent on early electrical defibrillati ...

    SBIR Phase II 2005 Department of Health and Human ServicesNational Institutes of Health
  8. A Novel Nutritional Intervention to Combat Osteoporosis

    SBC: Edenspace Systems Corporation            Topic: N/A

    DESCRIPTION (provided by applicant): Low levels of nutrients such as calcium contribute to osteoporosis and other significant health problems for millions of people worldwide. For many consumers, current methods of increasing dietary nutrients are inconvenient, costly, or unpalatable. This STTR Phase I project proposes to develop a novel method of increasing levels of one or more nutrients in veg ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Design of an Automated Psoriasis Treatment System

    SBC: Boston Array Technologies, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Up to 3 percent of populations worldwide have psoriasis. A large number of the patients with psoriasis can be treated using UV light exposure. We propose to employ a light modulating microchip based on recent Micro Electro Mechanical Systems (MEMS) technological developments to build an Automated Psoriasis Treatment System. The overall goal of Phase I a ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. Fermentation initiated antibiotic synthesis

    SBC: Promiliad Biopharma Incorporated            Topic: N/A

    DESCRIPTION (provided by applicant): This Phase I Small Business Technology Transfer study between Promiliad Biopharma Inc. and Ohio University is focused on a clear prototype demonstration of REBACS, the core technology of Promiliad Biopharma. REcombinant Biotechnology Assisted Combinatorial Synthesis (REBACS) is the use of synthetic and/or genetic approaches to the construction of high complexit ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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