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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202251 - 202260 of 207699 results
  1. Validating the performance and inclusivity of a novel functionally-informed predictive genetic test method for polygenic disease

    SBC: MARTINGALE LABS, INC.            Topic: 172

    PROJECT SUMMARY We now know that over 90% of causal variants for common diseases, including cardiovascular disease and many cancers, lie in non-coding regions of the genome. Therefore, a complete picture of common disease risk requires analyzing variants across the whole genome, not just the coding genome. Currently available methods to screen for common disease risk focus on monogenic coding vari ...

    SBIR Phase I 2023 Department of Health and Human ServicesNational Institutes of Health
  2. Validating the Superiority of Ultra-Scan Score-Level Fusion

    SBC: Ultra-Scan Corporation            Topic: A10171

    Ultra-Scan will leverage the company's previously developed multimodal fusion technology to quantify the accuracy and validate the performance of its Neyman-Pearson fusion software for use with mission critical tactical identification systems, verifying that a score level fusion matching capability is achievable. A platform independent interface will be developed to allow integration of Ultra ...

    SBIR Phase I 2011 Department of DefenseArmy
  3. VALIDATION & TESTING OF THE VAM2D COMPUTER CODE

    SBC: Hydrogeologic Inc.            Topic: N/A

    SEVERAL STATES ARE CURRENTLY SEEKING MUCH-NEEDED NEW LOW-LEVEL RADIOACTIVE DISPOSAL SITES IN ACCORDANCE WITH THE LOW-LEVEL RADIOACTIVE WASTE POLICY ACT OF 1980. ANY NEW COMMERCIALREQUIREMENT THAT A SITE BE CAPABLE OF BEING MODELED AND THATITS PERFORMANCE BE ASSURED FOR 500 YEARS. FOR MOST SITES, THE HYDROGEOLOGICAL AND RADIONUCLIDE TRANSPORT CHARACTERIS- TICS OF THE UNSATURATED ZONE ARE MAJOR FACT ...

    SBIR Phase II 1989 Nuclear Regulatory Commission
  4. VALIDATION & TESTING OF THE VAM2D COMPUTER CODE

    SBC: Hydrogeologic Inc.            Topic: N/A

    N/A

    SBIR Phase I 1988 Nuclear Regulatory Commission
  5. Validation and commercialization of a/LCI for detection of esophageal neoplasia

    SBC: Oncoscope, Inc.            Topic: NCI

    DESCRIPTION (provided by applicant): The objective of this research is to commercialize a device (the Oncoscope Panocyte system) used to guide biopsy selection in patients with Barrett's esophagus (BE) during standard endoscopy surveillance for early- stage esophageal cancer. Barrett's esophagus most often develops in patients with chronic acid reflux and is the strongest risk factor fo ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  6. Validation and Cryopreservation of Ligament Engineered from Human Bone Marrow

    SBC: STEL Technologies, LLC            Topic: NIAMS

    DESCRIPTION provided by applicant The founders of Skeletal Tissue Engineering Laboratory Technologies LLC STEL are researchers at the University of Michigan Our research team has developed an innovative and paradigm shifting approach to ligament tissue engineering and a unique methodology for ACL replacement This tissue engineered ligament technology offers the possibility of radical impr ...

    STTR Phase I 2015 Department of Health and Human ServicesNational Institutes of Health
  7. Validation and development of specific small molecule inhibitors of HTRA1 for tre

    SBC: CALCYTE THERAPEUTICS, INC.            Topic: NEI

    DESCRIPTION (provided by applicant): Age-related macular degeneration (AMD) is the most common cause of visual impairment of the elderly in developed countries. Despite its prevalence with the aging population, its etiology and pathogenesis are poorly understood and the treatment options are limited. CalCyte's scientific co-founder, Kang Zhang, reported that polymorphisms in the promoter of the ge ...

    SBIR Phase I 2010 Department of Health and Human ServicesNational Institutes of Health
  8. Validation and Early Commercialization of the ENVISAGE Assay, a Prognostic Test for Barrett's Esophagus

    SBC: CAPSULOMICS INC            Topic: 300

    Barrett’s esophagus (BE) is the strongest known risk factor for, and obligate precursor of, esophageal high- grade dysplasia (HGD) and adenocarcinoma (EAC). However, determining future neoplastic progression risk is quite challenging in BE patients: current risk estimation is based solely on highly variable, subjective, observer-dependent histopathologic diagnoses (i.e., non-dysplastic (ND), Low ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  9. Validation and early development of a blood-based rapid diagnostic test for sepsis endotypes

    SBC: INFLAMMATIX, INC.            Topic: 300

    ABSTRACT Sepsis, a systemic inflammatory condition, occurs as a complication of infection and in severe cases may be associated with acute and life-threatening organ dysfunction. In the US alone, sepsis claims ~270,000 lives each year among ~1.7 million patients diagnosed annually, and globally, sepsis-related mortality is estimated to account for 20% of total deaths. Although improvements in the ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  10. Validation and Evaluation of Remote, Interactive Teams of Autonomous Systems (VERITAS)

    SBC: APTIMA INC            Topic: OSD09T004

    different modes, while using different combinations of subsystems. This presents a challenge for the personnel validating the system during design and development; the number of combinations of environments, modes, and subsystems is exponential. They cannot all be tested, so an optimal subset of tests must be run. We propose to develop VERITAS: Validation and Evaluation of Remote, Interactive Tea ...

    STTR Phase I 2010 Department of DefenseNavy
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