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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202261 - 202270 of 207699 results
  1. Audiometric Earphone- Phase 1

    SBC: AUDIOLOGY, INC            Topic: N/A

    DESCRIPTION (provided by applicant): This project seeks to develop an earphone for diagnostic audiometry with features that will significantly increase the efficiency and decrease the cost of routine hearing testing. The most-often used earphones emply a supra-aural design that has several undesirable characteristics, including 1) an "occlusion effect", an artificial increase in sensitivity to bon ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  2. Rationally-Designed Synthetic Antithrombin Activators

    SBC: Novelmed Therapeutics Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Anticoagulation therapy with heparin- and low-molecular-weight (LMW) heparins, used in thrombotic and vascular disorders, has reached an annual cost of nearly $ 4 billion for the drugs alone. Yet heparin usage suffers from several problems, including bleeding complications, that may prove fatal. Consensus is growing that LMW heparins also suffer from similar pr ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  3. Chitosan hemostatic device for laparoscopic applications

    SBC: HemCon Medical Technologies Inc            Topic: N/A

    DESCRIPTION (provided by applicant): Intraoperative bleeding can be a serious problem in parenchymal organ surgery and is generally difficult to manage during laparoscopic procedures. Our long-term goal is to develop a novel internal chitosan hemostatic device that can be deployed laparoscopically to control severe bleeding. External chitosan based hemostatic dressings have been applied success ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  4. National EMS Patient Safety Reporting System

    SBC: Mepars, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): Specific data on errors, near misses, and adverse events occurring during emergency medical services (EMS) care do not exist. The recent Institute of Medicine report on medical error found emergency medicine (EM) to have the highest rate of preventable adverse events among the medical specialties. Although prehospital medical care has not been studied, it is re ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  5. Quantitation Pulmonary Delivery of Therapeutic Protein

    SBC: Arizeke Pharmaceuticals, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Arizeke Pharmaceuticals, Inc. is focused on the pulmonary delivery of protein therapeutics (including antibodies) to treat pulmonary disease. Arizeke's technology provides a unique ability to deliver large therapeutic proteins into the lung parenchyma and interstitium and into the lymphatic drainage system. Examples of indications that can be targeted by this t ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  6. Restoration of vestibular hair cells induced by AdMath1

    SBC: GENVEC, INC.            Topic: N/A

    Loss of vestibular hair cells can occur due to a variety of disorders and results in dysfunction of the vestibulo-occular reflex and loss of balance. Bilateral vestibular hypofunction due to aminoglycoside ototoxicity and other means is a devastating and currently untreatable chronic disorder because loss of vestibular hair cells is permanent. To date there is no prosthetic device such as a hearin ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  7. Novel epoxide hydrolase inhibitor for stroke prevention

    SBC: Arete Therapeutics, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): A major cause of morbidity and mortality is the progression of organ damage associated with cardiovascular diseases. For instance, the incidence of stroke and costs associated with stroke damage continues to have a devastating impact on public health despite numerous treatments aimed at cardiovascular risk factors. Recent findings indicate that increasing lev ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  8. Fiber Optic Array Based Bioluminesence Imaging

    SBC: Korima, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Bioluminescence imaging is a novel technique for visualizing biological processes within living animals. The cells or organism of interest are genetically modified to express luciferase, the enzyme that causes some insects, jellyfish, and bacteria to glow. Luciferase catalyzes a chemical reaction that generates light as one of its products. A highly sensitive ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  9. Utility of a Novel Anthracycline Analog in Psoriasis

    SBC: GEM Pharmaceuticals            Topic: N/A

    DESCRIPTION (provided by applicant): Psoriasis is a common immune-mediated disease that affects approximately 2% of the US and European populations and significantly impacts the quality of life. T cells are recognized as primary mediators of the disease and new generation therapies aimed at eliminating reactive T cells or interfering with the immunologic cascade caused by their activation have bee ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
  10. G-Protein Coupled Receptor Nanostructure Pharmaceutics

    SBC: Nanodisc, Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Membrane proteins play critical functions in many if not most cellular and physiological processes. Single membrane proteins and their macromolecular assemblies are essential catalysts in the metabolism and conveyance of information and energy between cells and the external environment, between cellular compartments and in the interactions of cells with viral ...

    SBIR Phase I 2005 Department of Health and Human ServicesNational Institutes of Health
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