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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202311 - 202320 of 207725 results
  1. Validation of a lab-free low-cost screening test for prevention of cervical cancer: automated visual evaluation

    SBC: MobileODT Inc.            Topic: 102

    PROJECT SUMMARY/ABSTRACT Artificial intelligence (AI) has the potential to revolutionize medicine by improving productivity, reducing human error, and assisting with diagnosis and treatment. Image classification algorithms can be used to develop automated visual evaluation (AVE): a potential game-changer for cervical cancer prevention in low- and middle-income countries (LMICs). AVE technology rea ...

    SBIR Phase I 2020 Department of Health and Human ServicesNational Institutes of Health
  2. Validation of a lab-free low-cost screening test for prevention of cervical cancer: automated visual evaluation

    SBC: DL Analytics LLC            Topic: 102

    PROJECT SUMMARY/ABSTRACT Artificial intelligence (AI) has the potential to revolutionize medicine by improving productivity, reducing human error, and assisting with diagnosis and treatment. Image classification algorithms can be used to develop automated visual evaluation (AVE): a potential game-changer for cervical cancer prevention in low- and middle-income countries (LMICs). AVE technology rea ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  3. Validation of Alcohol Exposure Biomarkers via Affinity Mass Spectrometry

    SBC: INTRINSIC BIOPROBES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The objective of this proposal is to validate potential biomarkers of excessive alcohol exposure discovered in the Phase 1 portion of this work (1R43AA016233-01). This will entail the development of pipettor tip based immuno-affinity mass spectrometry (AMS) devices for the routine and repetitive high throughput analysis of the biomarkers in question. Resultant ...

    SBIR Phase II 2009 Department of Health and Human ServicesNational Institutes of Health
  4. Validation of Amotosalen-HCI for Clinical Use

    SBC: CERUS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Amotosalen-HCI is a proprietary psoralen compound owned by Cerus Corporation, which has been developed for the inactivation of pathogens for the blood transfusion industry. Amotosalen-HCI is used in a photochemical process for the inactivation of pathogens in platelet concentrates and in fresh frozen plasma. AIIogeneic Cellular Immune Therapy (ACIT), another ph ...

    SBIR Phase I 2003 Department of Health and Human ServicesNational Institutes of Health
  5. Validation of Amotosalen-HCI for Clinical Use

    SBC: CERUS CORPORATION            Topic: N/A

    DESCRIPTION (provided by applicant): Amotosalen-HCI is a proprietary psoralen compound owned by Cerus Corporation, which has been developed for the inactivation of pathogens for the blood transfusion industry. Amotosalen-HCI is used in a photochemical pro

    SBIR Phase II 2004 Department of Health and Human ServicesNational Institutes of Health
  6. Validation of a Multiple Food-borne Pathogen Detection and Strain-Level Identification Assay

    SBC: TESSARAE, LLC            Topic: 85

    The primary objectives of this Phase II project are to 1) validate performance of the prototype resequencing pathogen microarray application for detection and identification of selected food-borne pathogens, including varieties of viruses, bacteria and eukaryotic agents; 2) iterate and port the prototype application to a more practical, "market-friendly" product form factor that requires less expe ...

    SBIR Phase II 2011 Department of Agriculture
  7. Validation of an Amphibian Lifecycle Test Method for Measuring Endocrine Disruption

    SBC: Fort Environmental Laboratories, Inc.            Topic: C3NCERPH

    The Phase I study resulted in the development of an assay that tests substances that have the capacity to disturb reproductive and developmental processes during the lifecycle of a vertebrate animal by interfering with the endocrine system. The primary goal of this Phase II research project is to standardize, validate, and commercialize an amphibian lifecycle model using Xenopus as a ...

    SBIR Phase II 2004 Environmental Protection Agency
  8. Validation of a Negative Regulator as a Novel Therapy for Autoimmune Disease

    SBC: IMMUNEXT PHARMACEUTICALS            Topic: NIAID

    DESCRIPTION (provided by applicant): The immune system depends upon an exquisite balance between positive and negative signals to maintain proper function. However, disruptions of this balance can lead to inappropriate responses: for example loss of negative regulation can result in autoimmunity. VISTA (V-region Immunoglobulin-containing Suppressor of T cell Activation), is a recently identified n ...

    STTR Phase I 2012 Department of Health and Human ServicesNational Institutes of Health
  9. Validation of a Negative Regulator as a Novel Therapy for Autoimmune Disease

    SBC: IMMUNEXT PHARMACEUTICALS            Topic: NIAID

    DESCRIPTION provided by applicant Systemic lupus erythematosus SLE is a devastating autoimmune disease that most commonly affects women in their child bearing years SLE attacks multiple organ systems but renal and neurologic involvement are the usual harbingers of poor outcome Despite effective albeit toxic immunosuppressive therapy only of patients with these serious manifestations ...

    STTR Phase II 2014 Department of Health and Human ServicesNational Institutes of Health
  10. Validation of a Neurogenic Bladder Management Solution to Promote Independence and Reduce Long-Term Morbidity for Patients Unable to Perform Intermittent Catheterization

    SBC: CRM MEDICAL DEVICES INC            Topic: 400

    PROJECT SUMMARY/ABSTRACT The primary objectives of this SBIR Phase II project are to verify the surgical approach for device placement, finalize device design, and complete Design Validation and Verification testing to support 510k submission for the EZ-SP device. CRM Medical Devices developed the EZ-SP catheter as a bladder drainage system for those who cannot volitionally void, with a specific e ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
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