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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202321 - 202330 of 207714 results
  1. Development of a Novel Method for Inhibiting Atherosclerosis in Diabetes

    SBC: VASCULAR PHARMACEUTICALS            Topic: N/A

    DESCRIPTION (provided by applicant): The long term objective of the proposed studies is to develop a monoclonal antibody that can be administered safely to patients with diabetes to determine if it can inhibit atherosclerosis. Insulin-like growth factor-l (IGF-I) has been implicated in initiating the proliferative phase of atherosclerotic lesion development but inhibiting IGF-I receptor activity m ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  2. Persistent Contrast Agent for Percent Infarct Map in MRI

    SBC: ELGAVISH PARAMAGNETICS, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The long term goal of this project is to establish the usefulness of a new infarct-avid, persistent contrast agent (PCA), Gd(ABE-DTTA), which due to its long lifetime in tissue allows construction of accurate relaxation-rate-enhancement(AR1)-based voxel-by-voxel viability maps of the acutely infarcted heart. Assisted by the slow tissue kinetics and infarct-spec ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  3. Research Developmental Cognitive Neuroscience

    SBC: Perception Research Systems Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): As the use of combined research modalities (EEC, fMRI and various behavioral assays) has become increasingly common in cognitive neuroscience studies, researchers have had to struggle with the lack of a single solution for interfacing these systems with their experimental control software. This presents a barrier to the efficient progress of much NIH-funded beh ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  4. Improvement of RNAi efficacy by blocking RNAi inhibitors

    SBC: SILENTECH, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): RNA Interference (RNAi) promises to become a powerful approach to rational drug design. One significant drawback to RNAi is that its effect on gene expression is rarely 100% potent. This limitation, observed widely, is problematic when a complete cessation of gene expression is desired or required. A major goal of this proposal is to develop targeted strategies ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  5. Restoration of Skin Structure and Function Post-Wounding

    SBC: FirstString Research, Inc            Topic: N/A

    DESCRIPTION (provided by applicant): The wound repair process in skin is initiated immediately after an injury and induces a cascade of events including inflammation, proliferation, and scar production/tissue remodeling. One of the common complications of wound healing is excessive scarring, leading to undesirable changes in skin mechanical function, as well as cosmetic disfiguration. The adverse ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  6. Laboratory mouse identification and inventory control

    SBC: MUSE TECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): Project Summary: The laboratory mouse is an essential experimental resource for modern biomedical research. Scientists currently use hundreds of varieties and strains of mice, and generate over 10 million individual animals each year. Tens of millions of dollars of NIH funding annually support mouse model research, with millions directly allocated to the mainte ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  7. Pre-clinical Feasibility Study of Tissue Oxygenation Imager

    SBC: Modulated Imaging Inc.            Topic: N/A

    DESCRIPTION (provided by applicant): Chronic wounds are non-healing wounds such as diabetic ulcers and pressure ulcers. Each year, 6.5 million cases occur in the U.S., costing the economy billions of dollars. Cost-effective and efficient management of chronic wounds depends on quick assessment and diagnosis of the underlying reasons for compromised healing. Ischemia is one of the main complication ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  8. Cloned pigs for Xenotransplantation

    SBC: EVERGEN BIOTECHNOLOGIES, INC.            Topic: N/A

    DESCRIPTION (provided by applicant): The purpose of the proposed research is to develop methods to create immune protected universal donor cloned transgenic pigs for xenotransplantation. According to the United Network of Organ Sharing (UNOS) more than 30,000 organ transplants are performed in the US alone, yet greater than 95,000 people are currently on the waiting list to receive donors organs f ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  9. SRF/MYOCD: new targets in Alzheimer's neurovasculature

    SBC: SOCRATECH, LLC            Topic: N/A

    DESCRIPTION (provided by applicant): There is no organ in the body as dependent on a continuous supply of blood as the brain. If cerebral blood flow (CBF) is interrupted, brain function ceases within seconds and irreversible damage to its cellular constituents ensues within minutes. In elderly patients, increasing evidence suggests that vascular risk factors and lowered CBF have a major role in ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
  10. Development of SAMMA based vaginal microbiocide

    SBC: YASO THERAPEUTICS INCORPORATED            Topic: N/A

    DESCRIPTION (provided by applicant): To date, the scientific and political focus of sexually transmitted infection (STI) prevention through education, condom use, and vaccine research is clearly inadequate. HIV, Chlamdia, gonorrhea, HSV, and HPV continue to spread, particularly via heterosexual transmission. The tragic reality is that most women are powerless to protect themselves and their unborn ...

    SBIR Phase I 2006 Department of Health and Human ServicesNational Institutes of Health
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