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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202341 - 202350 of 207728 results
  1. Medical countermeasure after radiation exposure

    SBC: PHARMAIN CORPORATION            Topic: NIAID

    DESCRIPTION provided by applicant New treatments for radiation injury to the GI tract are desperately needed to ensure survival after exposure to ionizing radiation arising from accident nuclear warfare or terrorist attacks dirty bombs Radiation injuries to the hematopoietic system and the GI tract are fatal with the latter more acutely fatal No treatment is available fo the more acute l ...

    SBIR Phase I 2014 Department of Health and Human ServicesNational Institutes of Health
  2. Development of Chemistry, Manufacturing, and Control Standards for PGC and PGC-dANP

    SBC: PHARMAIN CORPORATION            Topic: NHLBI

    ABSTRACTThis application is seeking funding specifically for ChemistryManufacturingand ControlCMCof scale up production of long acting atrial natriuretic peptidedANPand its protected graft co polymerPGCexcipient for use in heart failureHFtreatmentThe extrinsic merit of this project will be the availability of cGMP grade PGC for use in prolonging the half life of various peptide drugs that are in p ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  3. Subcutaneous Drug Development for Portal Hypertension Ascites

    SBC: PHARMAIN CORPORATION            Topic: NIDDK

    ABSTRACT: The prevalence of all types of ascites, irrespective of the cause, is 41.7 in 100,000 with 80% of these due to cirrhosis. Ascites is treated with a salt restricted diet and pharmacologic therapy using diuretics. However, in 5% to 10% of patients with ascites becomes refractory to medical therapy. Half of patients who develop refractory ascites due to advanced liver cirrhosis will die wit ...

    SBIR Phase II 2021 Department of Health and Human ServicesNational Institutes of Health
  4. CMC of Peptide Formulation for the Treatment of ARDS

    SBC: PHARMAIN CORPORATION            Topic: NHLBI

    ABSTRACT: Without a pandemic such as COVID-19, the prevalence of Acute Respiratory Syndrome (ARDS) associated with Acute Lung Injury (ALI) is estimated to be ~200-240K patients/year in the US, accounting for 3.6-million hospital days per year and with 30-40% mortality. Considering that US represent only 4.23 % of world population, the likely incidence of ARDS and commercially addressable needs wil ...

    SBIR Phase I 2022 Department of Health and Human ServicesNational Institutes of Health
  5. CMC of Peptide Formulation for the Treatment of ARDS

    SBC: PHARMAIN CORPORATION            Topic: NHLBI

    ABSTRACT: Without a pandemic such as COVID-19, the prevalence of Acute Respiratory Syndrome (ARDS) associated with Acute Lung Injury (ALI) is estimated to be ~200-240K patients/year in the US, accounting for 3.6-million hospital days per year and with 30-40% mortality. Considering that US represent only 4.23 % of world population, the likely incidence of ARDS and commercially addressable needs wil ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  6. Development of an immunomodulating peptide as a therapy for osteosarcoma in canine and human

    SBC: PHARMAIN CORPORATION            Topic: 102

    Osteosarcoma (OSA) is the most common primary malignancy of bone in children and adolescents, accounting for approximately 5% of all childhood tumors (www.cancer.gov). Osteosarcoma occurs primarily in the long bones of the limbs, including most commonly the femur, tibia, and humerus1. The current standard of care therapy for human patients diagnosed with OSA includes multi-agent neoadjuvant chemot ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
  7. A Standards Based, Open-Architecture, Ruggedized Tactical Microgrid Controller

    SBC: OPEX SYSTEMS, LLC            Topic: OSD12EP4

    The Army is addressing a technical challenge of constrained data interface to vendor supplied equipment, to integrate Energy Storage (ES) and tactical Energy Assets (EA) to improve fuel efficiency and reduce wear. The Phase I effort will investigate the feasibility of developing a ruggedized Intelligent Power Management Controller (IPMC) which will act as (a) an Universal Data Integration Gatew ...

    SBIR Phase I 2013 Department of DefenseArmy
  8. Improved AM quality using analytics on low-cost, COTS, in situ sensor data

    SBC: OPEX SYSTEMS, LLC            Topic: DLA193002

    Premature field-failures of Additive Manufacturing (AM) produced parts, intended for use in a variety of mission-critical industrial, military and aerospace applications, could lead to catastrophic consequences. Detecting emerging out-of-tolerance conditions using a multitude of low-cost, in situ process sensors, and applying mathematical algorithms to provide real-time operator feedback could sig ...

    SBIR Phase I 2020 Department of DefenseDefense Logistics Agency
  9. A Novel, Modular, AC-DC Integrated, Li-Ion 6T Energy Storage Technology

    SBC: OPEX SYSTEMS, LLC            Topic: A20047

    The Army is seeking a novel, inverter-integrated 6T, Li-Ion (LiFePO4) battery module suitable for highly-agile tactical operational energy (OE) needs. We are proposing an R&D effort to develop a compact and modular product called “ACDC-6T” to address this need innovatively. This technology will incorporate several innovative component technologies integrated to achieve superior power and energ ...

    SBIR Phase I 2020 Department of DefenseArmy
  10. Novel Technology to Secure and Enhance the Resiliency of Air Force High-Speed Networks, with Multiple Use-Cases

    SBC: OPEX SYSTEMS, LLC            Topic: AF203CSO1

    Maintaining absolute security of existing network infrastructure and adopting emerging next generation network technologies: 5G, multi-GB and Cloud infrastructure is a priority for the Air Force (AF). High-speed networks connecting sensors, OT/IoT and autonomous systems will become prevalent in smart - depot, tactical edge and asset (e.g. aircraft, ship) operations. However, as networks scale, cyb ...

    SBIR Phase I 2021 Department of DefenseAir Force
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