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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 202371 - 202380 of 207699 results
  1. Validation of Red Blood Cell Mechanical Fragility as a Metric for Assessing Blood Damage Caused by Implantable Ventricular Assist DEvices

    SBC: Blaze Medical Devices            Topic: FDA

    DESCRIPTION provided by applicant Blaze Medical Devices Blaze is developing a rapid integrated test for RBC mechanical fragility MF as a potential indicator of safety and performance of blood handling devices The safety and performance of blood handling devices such as VADs are evaluated by hemocompatibility testing to assess the damage they inflict upon red blood cells RBC The chief in ...

    SBIR Phase I 2015 Department of Health and Human ServicesFood and Drug Administration
  2. Validation of Segmented Flanges for Large Diameter Wind Turbine Towers

    SBC: Keystone Tower Systems, Inc.            Topic: 86

    At sites ranging from Texas to Iowa, utility scale wind has become the lowest cost electricity source available, with recent prices well below 3cents/kWhr, lower than the cost of both coal and shale gas. This not only provides these communities with clean, low cost energy, it also provides a valuable "second crop" to the land owners in these areas. However, this opportunity is currently limited to ...

    SBIR Phase II 2016 Department of Agriculture
  3. VALIDATION OF SERUM BIOASSAY FOR DIOXIN-LIKE TOXICANTS

    SBC: XENOBIOTIC DETECTION SYSTEMS            Topic: N/A

    N/A

    SBIR Phase II 1998 Department of Health and Human Services
  4. VALIDATION OF SERUM BIOASSAY FOR DIOXIN-LIKE TOXICANTS

    SBC: XENOBIOTIC DETECTION SYSTEMS            Topic: N/A

    N/A

    SBIR Phase I 1996 Department of Health and Human Services
  5. VALIDATION OF SHADE A MOBILE TECHNOLOGY FOR MONITORING OF ULTRAVIOLET EXPOSURE

    SBC: YOUV LABS            Topic: NCI

    Shade helps people manage their UV exposure it is a ultraviolet UV monitor with unprecidented accuracyconnected to a mobile application Although it is one of the clearest and most controllable causes of cancer UV exposure can be difficult to estimate due to the importance of combining many rapidly changing factors including intensity shade and use of protective cloting and sunscreen To val ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  6. Validation of ShuntCheck-Micro-Pumper, a non-invasive diagnostic procedure for de

    SBC: NEURODX DEVELOPMENT LLC            Topic: NINDS

    DESCRIPTION (provided by applicant): This Phase 2 SBIR will provide and clinically validate the first portable, non-invasive diagnostic test for differentiating intermittently flowing patent shunts from occluded or partially occluded shunts - ShuntCheck- Micro-Pumper. This device will result in improved clinical management of hydrocephalus by providing a rapid and non-invasive method for detec ...

    SBIR Phase II 2011 Department of Health and Human ServicesNational Institutes of Health
  7. Validation of SPX as a candidate for the treatment of cystic fibrosis

    SBC: SPYRYX LLC            Topic: NHLBI

    The Epithelial Na Channel ENaC is the rate limiting step for Na absorption across many epithelia In the airways of cystic fibrosis CF patients ENaC is abnormally hyperactive leading to disproportionate Na absorption and a depletion of airway surface liquid ASL volume ENaC hyperactivity contributes to mucus stasis and increased incidence of airway infections that frequently lead to the ...

    SBIR Phase I 2017 Department of Health and Human ServicesNational Institutes of Health
  8. Validation of Standing Wave Liner Impedance Measurement Method

    SBC: Hersh Acoustical Engineering, Inc.            Topic: A102

    Hersh Acoustical Engineering, Inc. proposes to establish the feasibility and practicality of using the Standing Wave Method (SWM) to measure the impedance of perforate-over-honeycomb liners exposed to both grazing and orifice bias flow. By measuring liner generated reflected sound in a duct, the SWM calculates the impedance of one or more rows of resonator liners, providing the liner axial length ...

    SBIR Phase I 2016 National Aeronautics and Space Administration
  9. Validation of targets for therapeutic intervention in NASH

    SBC: HemoShear Therapeutics, LLC            Topic: 300

    Direct to Phase II SBIRValidation of targets for therapeutic intervention in NASHABSTRACT Non alcoholic steatohepatitisNASHis part of the progressive disease spectrum of non alcoholic fatty liver diseaseNAFLDa public health crisis affectingof typediabetics andof obese individualsGlucoseand insulin regulated de novo lipogenesis in the livera critical step in the disease processis severely compromis ...

    SBIR Phase II 2017 Department of Health and Human ServicesNational Institutes of Health
  10. Validation of the Genetically Malleable Oncopig Hepatocellular carcinoma (HCC) Model for Targeted Therapeutic Development

    SBC: SUS CLINICALS INC            Topic: 102

    PROJECT ABSTRACT: The goal of this Phase II SBIR proposal is to further validate the genetically defined Oncopig hepatocellular carcinoma (HCC) model—capable of modeling diverse HCC driver mutational profiles through induced KRASG12D and TP53R167H expression and subsequent CRISPR editing—for preclinical evaluation of locally delivered, personalized HCC therapies. HCC is an aggressive liver mal ...

    SBIR Phase II 2023 Department of Health and Human ServicesNational Institutes of Health
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