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The Award database is continually updated throughout the year. As a result, data for FY24 is not expected to be complete until March, 2025.

Download all SBIR.gov award data either with award abstracts (290MB) or without award abstracts (65MB). A data dictionary and additional information is located on the Data Resource Page. Files are refreshed monthly.

The SBIR.gov award data files now contain the required fields to calculate award timeliness for individual awards or for an agency or branch. Additional information on calculating award timeliness is available on the Data Resource Page.

Displaying 204451 - 204460 of 207728 results
  1. Treating Drivers of Suicide in Primary Care using Jaspr Health

    SBC: EVIDENCE-BASED PRACTICE INSTITUTE, INC.            Topic: 350

    PROJECT SUMMARY/ABSTRACTSuicide remains a serious public health problem in the U.S. as rates have risen nearly each year since 2005, from 11.0 per 100,000 to 14.8 per 100,000 in 2018, totaling 48,344 in 2018; 1.4 million U.S. adults made a suicide attempt, and another 12 million thought seriously about killing themselves that same year. Alcohol use disorder (AUD) exponentially increases suicide ri ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  2. Toward GMP production of antigen specific regulatory T cells

    SBC: DIAGNOLOGIX, LLC            Topic: 102

    ABSTRACT There is an unmet need for more selective and sustainable therapeutics to treat a growing number of immune- related diseases. For example, autoimmune disorders affect more than 50 million patients in the United States alone and there was a 3.4% annual increase in type 1 diabetes among European children between 1989 and 2013. While conventional treatments may alleviate symptoms, they are o ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  3. Automated Contact Tracing System for Rapid High-Accuracy Assessment to Management Dementia Patients and Staff Exposed to Infectious Diseases in Long Term Care Facilities

    SBC: ASTER LABS, INC.            Topic: NIA

    Project Abstract In this Fast-Track SBIR project, ASTER Labs will address an urgent, immediate, need for accessible and accurate contact tracing to aid management of infectious disease outbreaks in long-term care facilities of patients with Alzheimer’s disease and related dementias. An estimated 5.8 million Americans in 2020 live with Alzheimer’s dementia and nearly half of nursing home and ot ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  4. Ultra-high content analyses of circulating and solid tumor cells: A diagnostic reference system for disease burden

    SBC: QUANTITATIVE IMAGING SYSTEMS LLC            Topic: 102

    ABSTRACT We propose to create a modular suite of products to facilitate highly multiplexed imaging and quantita- tive analyses of individual cells in intact tissue, and cells circulating in blood to be used to establish disease status. Our imaging software analyses platform supporting interactive data visualization will connect protein-based cellular features between tissue resident cells and diss ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  5. Wide-Field Quantitative Fluorescence Imaging System

    SBC: InSight Surgical Technologies LLC            Topic: 102

    PROJECT SUMMARY In this Fast Track (Phase I + Phase II) SBIR application, we will evaluate feasibility (in Phase I) of an accurate, fast and low-cost instrument (qF-ImageTM) design for accurate wide-field imaging of the absolute concentration of the fluorophore PpIX (CPpIX) in the surgical field for guiding brain tumor resection, and demonstrate that design meets quantitative end-user specificatio ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  6. Development of Nav1.1 Enhancers to Treat Alzheimer's Disease

    SBC: Cure Network Dolby Acceleration Partners LLC            Topic: R

    ABSTRACT CNDAP is developing a new class of drugs, acting through a unique mechanism of action, to reverse early pathophysiological and cognitive alterations in Alzheimer’s disease (AD). Recent studies indicate that network dysfunction, which includes network hyperactivity, altered oscillatory rhythms, and hyper- synchronized networks, is an early pathogenic event found in preclinical models of ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  7. SSW Works: A Virtual Learning Environment for Occupational Skin Cancer Prevention

    SBC: KLEIN BUENDEL, INC.            Topic: 102

    Americans who work outdoors are exposed to an extreme amount of solar ultraviolet radiation (UV) over a lifetime that substantially increases their risk for developing skin cancer. Annually, skin cancer is diagnosed in over 3.5 million U.S. adults, melanoma kills nearly 7,000 Americans, and treatment costs at least $8 billion. The U.S. Surgeon General has identified occupational sun safety as a na ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  8. Preclinical development of CM-CX1 for the treatment of ovarian clear cell and renal cell carcinomas

    SBC: CELDARA MEDICAL, LLC            Topic: 102

    PROJECT SUMMARY Cancer is one of the leading causes of death worldwide. Over the years, a number of conventional cytotoxic approaches for neoplastic diseases has been developed. However, due to their limited effectiveness in accordance with the heterogeneity of cancer cells, there is a constant search for therapeutic approaches with improved outcome, such as immunotherapy that utilizes and enhance ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  9. Design, Development, and Validation of an AI-enabled Legal Planning and Financial Management Training Solution for ADRD Caregivers

    SBC: Whiplash Technology, Inc.            Topic: NIA

    PROJECT ABSTRACT More than 16 million caregivers (‘family members or friends’) of people with Alzheimer’s disease and related dementias (ADRD) face serious challenges in providing care. ADRD caregivers are frequently tasked with substantial and overwhelming legal and financial planning, and they face increased financial risk and strain as a result. Currently, there is no widely available web ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
  10. Diversity supplement for noninvasive, wireless thermal sensors for the quantitative monitoring of ventricular shunt function in patients with hydrocephalus

    SBC: RHAEOS, INC            Topic: 102

    ABSTRACTHydrocephalus is a neurological disorder caused by buildup of excess cerebrospinal fluid (CSF) in the brain, and leads to lethargy, seizures, coma, or death. It is treated with the surgical implantation of a catheter, known as a ventricular shunt, that diverts excess CSF away from the brain and into a distal absorptive site, such as the abdomen. Unfortunately, due to occlusion or mispositi ...

    SBIR Phase II 2022 Department of Health and Human ServicesNational Institutes of Health
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